Results 1 to 10 of about 1,506 (195)
Allergology International, 2023 Chronic spontaneous urticaria (CSU) is a common skin disease without an etiology in the vast majority of cases. The similarity of symptoms and pathology to allergen-induced skin reactions supports that skin mast cell IgE receptor activation is also ...
Sarbjit S. Saini
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Allergology International, 2021 Background: Although basophils are considered to play an important role for maintenance of type 2 inflammation in atopic dermatitis (AD), studies on basophils in AD patients are limited.
Shinya Imamura +5 more
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Nature Communications, 2023 Basophils are the rarest granulocytes and are recognized as critical cells for type 2 immune responses. However, their differentiation pathway remains to be fully elucidated.
Kensuke Miyake +5 more
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Journal of Clinical Investigation, 1980 Factors influencing basophil production from the bone marrow of ovalbumin (OA)-sensitized guinea pigs have been examined in vitro. Autologous co-cultures of marrow and spleen cells from OA-immune animals contained significantly higher numbers of basophils after 7 d of liquid culture in the presence of OA, compared with control co-cultures or with ...
J A, Denburg, M, Davison, J, Bienenstock
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IgE Autoreactivity in Atopic Dermatitis: Paving the Road for Autoimmune Diseases?
Antibodies, 2020 Atopic dermatitis (AD) is a common skin disease affecting 20% of the population beginning usually before one year of age. It is associated with the emergence of allergen-specific IgE, but also with autoreactive IgE, whose function remain elusive.
Christophe Pellefigues
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The roles of basophils in mediating the immune responses
European Journal of Inflammation, 2021 Basophils are the rarest blood cell population and have not been extensively studied. Our understanding of the functions of basophils is limited to their roles as the main effector cells in hypersensitivity reactions.
Na Zhang, Ze-Ming Zhang, Xiao-Fei Wang
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Is There a Role for Basophils in Cancer?
Frontiers in Immunology, 2020 Basophils were identified in human peripheral blood by Paul Ehrlich over 140 years ago. Human basophils represent <1% of peripheral blood leukocytes.
Giancarlo Marone +18 more
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Basophils as a potential marker of lupus nephritis by flow cytometry
Future Science OA, 2021 Objective: To establish a convenient and simple flow cytometry immunophenotyping panel to explore immune cellular alterations and potential cellular biomarkers in systemic lupus erythematosus.
Yanni Jiang +5 more
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Eosinophils, Basophils, and Neutrophils in Bullous Pemphigoid
Biomolecules, 2023 Bullous pemphigoid (BP) is an autoimmune blistering skin disease, of which the incidence has increased in recent years. BP is characterized by circulating IgG and IgE autoantibodies against the hemidesmosomal proteins BP180 and BP230.
Maren M. Limberg +5 more
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Frontiers in Immunology, 2023 Basophils crucially contribute to allergies and other Th2-driven diseases by rapidly releasing inflammatory and immunomodulatory mediators following high-affinity IgE-receptor crosslinking.
Anette T. Hansen Selnø +3 more
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