Results 91 to 100 of about 56,684 (297)
Food Safety and Health, EarlyView.Withania somnifera seed extract and powder improved metabolic parameters in rats, particularly at higher extract doses, without evident hepatic, renal, hematological, or histopathological toxicity. Molecular docking further predicted strong DPP‐4 inhibitory potential of withanone, supporting the antidiabetic potential of W. somnifera seeds.
Muhammad Usman Khalid +8 more
wiley +1 more source
Basophils, IgE, and Autoantibody-Mediated Kidney Disease
, 2011 Basophils are of interest in immunology due to their ability to produce a Th2-signature cytokine, IL-4, following activation. A new understanding of the role of basophils in immunity shows novel functions at a cellular level through which basophils ...
Ricard Cervera +4 more
core +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos +10 more
wiley +1 more source
Retroviral transduction in cultured murine basophils
, 2015 <p>Basophils are one of effector cells in type 2 immune responses that critically are associated with allergic inflammation and infections with helminth parasites.
sprotocols
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Journal of Clinical Laboratory Analysis, EarlyView.This cross‐sectional study evaluated the feasibility of applying machine learning for complete blood count autoverification. Among 63,201 CBC results, the XGBoost model achieved higher sensitivity and predictive values compared with the traditional rule‐based system. ABSTRACT Background Autoverification improves laboratory efficiency by reducing manual
Sinsorn Srirujee +1 more
wiley +1 more source
Tristetraprolin-mediated mRNA destabilization regulates basophil inflammatory responses
Allergology InternationalBackground: Basophils, despite being the least common granulocytes, play crucial roles in type 2 immune responses, such as chronic allergic inflammation and protective immunity against parasites.
Junya Ito +7 more
doaj +1 more source
IL-3 but not monomeric IgE regulates FcεRI levels and cell survival in primary human basophils. [PDF]
, 2018 Binding of allergen-specific IgE to its primary receptor FcεRI on basophils and mast cells represents a central event in the development of allergic diseases. The high-affinity interaction between IgE and FcεRI results in permanent sensitization of these
Patrick Buschor +13 more
core +2 more sources
Journal of Clinical Laboratory Analysis, EarlyView.Primary immune thrombocytopenia (ITP) and connective tissue disease‐related thrombocytopenia (CTD‐TP) share overlapping initial presentations in children, often leading to delayed diagnosis and suboptimal management. While existing literature focuses on therapeutic strategies, this study is the first to develop a machine learning (ML)‐based diagnostic ...
Furong Kang +4 more
wiley +1 more source
Bee pollen as functional food and environmental bioindicator: current evidence and future challenges
Journal of the Science of Food and Agriculture, EarlyView.Abstract Bee pollen (BP), a plant‐derived product collected by honey bees, is increasingly promoted as a functional food due to its content of proteins, essential amino acids, lipids, vitamins, minerals, and bioactive compounds such as polyphenols and flavonoids.
Luigi Parrotta, Stefano Del Duca
wiley +1 more source
Possible roles of basophils in chronic itch
, 2018 Basophils are blood granulocytes and normally constitute
Gil Yosipovitch +7 more
core +1 more source