Results 21 to 30 of about 1,506 (195)
Clinical and Translational Allergy, 2022 Background IgE and high‐affinity IgE receptor (FcεRI) expression on basophils have been scarcely explored in patients with chronic inducible urticaria (CIndU).
Ana M. Giménez‐Arnau +5 more
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UDP/P2Y6 receptor signaling regulates IgE-dependent degranulation in human basophils
Allergology International, 2017 Background: P2Y purinergic receptors (P2YR) are G protein-coupled receptors that are stimulated by extracellular nucleotides. They mediate cellular effects by regulating cAMP production, protein kinase C activation, inositol trisphosphate generation, and
Manabu Nakano +7 more
doaj +1 more source
SARS-CoV-2 Induces Cytokine Responses in Human Basophils
Frontiers in Immunology, 2022 Basophils play a key role in the orientation of immune responses. Though the interaction of SARS-CoV-2 with various immune cells has been relatively well studied, the response of basophils to this pandemic virus is not characterized yet.
Srinivasa Reddy Bonam +8 more
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Differential usage of COX-1 and COX-2 in prostaglandin production by mast cells and basophils
Biochemistry and Biophysics Reports, 2017 Basophils have been erroneously considered as minor relatives of mast cells, due to some phenotypic similarity between them. While recent studies have revealed non-redundant roles for basophils in various immune responses, basophil-derived effector ...
Tomoyuki Bando +6 more
doaj +1 more source
Basophils Orchestrating Eosinophils’ Chemotaxis and Function in Allergic Inflammation
Cells, 2021 Eosinophils are well known to contribute significantly to Th2 immunity, such as allergic inflammations. Although basophils have often not been considered in the pathogenicity of allergic dermatitis and asthma, their role in Th2 immunity has become ...
Joseena Iype, Michaela Fux
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Basophils from allergy to cancer
Frontiers in Immunology, 2022 Human basophils, first identified over 140 years ago, account for just 0.5-1% of circulating leukocytes. While this scarcity long hampered basophil studies, innovations during the past 30 years, beginning with their isolation and more recently in the ...
Remo Poto +15 more
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The Basophilic Granulocyte [PDF]
Blood, 1959 Abstract 1. The history, morphology and technics of counting of basophils have been briefly reviewed. 2. A marked relative and absolute increase of basophils was always found in chronic myelogenous leukemia. Moderate relative and absolute increases of basophils usually occurred in myeloid metaplasias (including ...
R E, FREDRICKS, W C, MOLONEY
openaire +2 more sources
Biomarkers for Allergen Immunotherapy in Cedar Pollinosis
Allergology International, 2009 To initiate, monitor, and complete effective immunotherapy, biomarkers to predict and visualize the immune responses are needed. First, we need to identify the right candidate for immunotherapy.
Takao Fujisawa +9 more
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Effect of brimonidine tartrate on basophil activation in glaucoma patients
International Journal of Ophthalmology, 2020 AIM: To evaluate the mechanism of which brimonidine tartrate 0.15% causes clinical hypersensitivity. METHODS: A prospective case-control study comparing 8 glaucoma patients with clinical hypersensitivity to brimonidine to a control group consisting 13 ...
Eldar Rosenfeld +7 more
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Interactions between Innate Lymphoid Cells and Cells of the Innate and Adaptive Immune System
Frontiers in Immunology, 2017 Type 2 innate lymphoid cells (ILC2s) are a major source of cytokines, which are also produced by Th2 cells and several cell types of the innate immune system.
Cornelia Symowski, David Voehringer
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