Results 31 to 40 of about 1,506 (195)
Basophils from Cancer Patients Respond to Immune Stimuli and Predict Clinical Outcome
Cells, 2020 Basophils are involved in manifestations of hypersensitivity, however, the current understanding of their propensity for activation and their prognostic value in cancer patients remains unclear.
Heather J. Bax +19 more
doaj +1 more source
Skin-homing basophils and beyond
Frontiers in Immunology, 2022 Basophils have been implicated in type 2 inflammation and numerous disorders in the skin such as helminth infection, atopic dermatitis, and urticaria.
Rintaro Shibuya +6 more
doaj +1 more source
MHC class II expression in human basophils: induction and lack of functional significance. [PDF]
PLoS ONE, 2013 The antigen-presenting abilities of basophils and their role in initiating a Th2 phenotype is a topic of current controversy. We aimed to determine whether human basophils can be induced to express MHC Class II and act as antigen presenting cells for T ...
Astrid L Voskamp +4 more
doaj +1 more source
Basophils control T cell priming through soluble mediators rather than antigen presentation
Frontiers in Immunology, 2023 Basophils play an important role in the development of type 2 immunity and have been linked to protective immunity against parasites but also inflammatory responses in allergic diseases.
Christian Möbs +4 more
doaj +1 more source
Immunity, 2008 In this issue of Immunity, Tsujimura et al. (2008) report that the release of platelet-activating factor by basophils stimulated with immunoglobulin G1 (IgG1)-antigen immune complexes contributes substantially to the expression of an IgG1-dependent alternative pathway of systemic anaphylaxis in mice.
Galli, Stephen J. +1 more
openaire +2 more sources
Role of Basophils in a Broad Spectrum of Disorders
Frontiers in Immunology, 2022 Basophils are the rarest granulocytes and have long been overlooked in immunological research due to their rarity and similarities with tissue-resident mast cells.
Kensuke Miyake +2 more
doaj +1 more source
Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang +10 more
wiley +1 more source
Analysis of Peripheral Blood Basophils in Pediatric Systemic Lupus Erythematosus
Diagnostics, 2022 Basophils are the least abundant circulating leukocytes, and their immunological role has not yet been completely elucidated. There is evidence supporting their immunomodulatory role in several pathological settings; recently, studies in both ...
Kuanysh Dossybayeva +7 more
doaj +1 more source
Arthritis Care &Research, Accepted Article.Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical frailty index (FI).
Grace Burns +2 more
wiley +1 more source
Advanced Science, EarlyView.IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang +15 more
wiley +1 more source