Nerve growth factor, brain-derived neurotrophic factor, and the chronobiology of mood: a new insight into the "neurotrophic hypothesis" [PDF]
, 2015 The light information pathways and their relationship with the body rhythms have generated a new insight into the neurobiology and the neurobehavioral sciences, as well as into the clinical approaches to human diseases associated with disruption of ...
IANNITELLI, ANGELA +2 more
core +2 more sources
BDNF deregulation in Rett syndrome [PDF]
Neuropharmacology, 2014 BDNF is the best-characterized neurotrophin in terms of its gene structure and modulation, secretion processing, and signaling cascades following its release. In addition to diverse features at the genetic and molecular levels, the abundant expression in several regions of the central nervous system has implicated BDNF as a potent modulator in many ...
Lucas Pozzo-Miller, Wei Li
openaire +3 more sources
Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy
Advanced Therapeutics, EarlyView.This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar +7 more
wiley +1 more source
The effect of aerobic exercise in an enriched environment on serum levels of brain-derived neurotrophic factor (BDNF), triglycerides, and glucose in active elderly men [PDF]
فصلنامه ابن سینا, 2020 Background: The neuroprotective effects of aerobic exercise and the enriched environment have been demonstrated, but the acute effects of aerobic exercise in the enriched environment have not been studied.
Hadis Mehrabi Fard +2 more
doaj
BDNF is a mediator of glycolytic fiber-type specification in mouse skeletal muscle
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance The brain-derived neurotrophic factor (BDNF) is essential to promote neuronal differentiation, plasticity, and survival. Altered BDNF expression is associated with several pathologies, including neuropsychiatric and neurodegenerative ...
Julien Delezie +9 more
semanticscholar +1 more source
Glucocorticoid receptor action in metabolic and neuronal function [version 1; referees: 3 approved] [PDF]
, 2017 Glucocorticoids via the glucocorticoid receptor (GR) have effects on a variety of cell types, eliciting important physiological responses via changes in gene expression and signaling.
Garabedian, Michael J +2 more
core +3 more sources
Lecithin Alleviates Memory Deficits and Muscle Attenuation in Chinese Older Adults and SAMP8 Mice
Advanced Science, EarlyView.This study opens a new avenue for safeguarding cognition and muscle health, averting disability in older age, and treating age‐related pathologies through lecithin supplementation. It serves as a promising nonpharmacological intervention for the crosstalk of muscle and cognition.
Xianyun Wang +16 more
wiley +1 more source
Neurobiology of local and intercellular BDNF signaling
Pflügers Archiv: European Journal of Physiology, 2017 Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family of secreted proteins. Signaling cascades induced by BDNF and its receptor, the receptor tyrosine kinase TrkB, link neuronal growth and differentiation with synaptic ...
Manju Sasi +3 more
semanticscholar +1 more source
Sophisticated sperm allocation in male fowl [PDF]
, 2003 When a female is sexually promiscuous, the ejaculates of different males compete for the fertilization of her eggs; the more sperm a male inseminates into a female, the more likely he is to fertilize her eggs.
Pizzari, T. +4 more
core +1 more source
The effect of depression, BDNF gene val66met polymorphism and gender on serum BDNF levels
Brain Research Bulletin, 2010 To determine the effect of BDNF gene val66met polymorphism on serum BDNF levels in drug-free patients with major depressive disorder (MDD) and healthy subjects, that differ by gender.Sixty-six drug-free patients (19 males+47 females) with non-psychotic MDD and fifty-six healthy controls (18 males+38 females) were recruited. Three-way ANOVA was employed
Ozan, Erol +5 more
openaire +4 more sources