Results 81 to 90 of about 13,381 (238)

Exercise-induced ‘browning’ of adipose tissues [PDF]

, 2017
Global rates of obesity continue to rise and are necessarily the consequence of a long-term imbalance between energy intake and energy expenditure. This is the result of an expansion of adipose tissue due to both the hypertrophy of existing adipocytes ...
Albrecht, Antonopoulos, Arner, Barreau, Berry, Bloor, Bogardus, Bordbar, Bostrom, Cannon, Carriere, Chaudhuri, Coelho, Craig Sale, Cypess, de Jong, De Matteis, Despres, Despres, Despres, Disanzo, DiSpirito, During, Emre, Fischer, Follenius, Fromme, Gagnon, Giralt, Haczeyni, Helen Budge, Hetzler, James Betts, Jespersen, Joyner, Kammoun, Kazak, Knudsen, Larue-Achagiotis, Liu, Long, M, Ma, Magkos, Maloney, Margaritis, Mark Pope, Marker, Matsushita, Michael E. Symonds, Nakhuda, Nielsen, Nozu, Oelkrug, Ostrowski, Palmer, Patsouris, Peppler, Peter Aldiss, Powers, Rao, Razzoli, Robciuc, Ronn, Sacks, Sanchez-Gurmaches, Scheele, Schreiber, Scott, Sengenes, Sepa-Kishi, Shabalina, Shimizu, Shin, Sidossis, Singhal, Stanford, Takx, Thomas, Thompson, Trayhurn, Tsiloulis, Tsoli, van Marken Lichtenbelt, Vergnes, Vieira, Virtanen, Vosselman, Woods, Wu, Wu, Yamashita, Yoneshiro   +92 more
core   +3 more sources

Weight Loss‐Associated Remodeling of Adipose Tissue Immunometabolism

Obesity Reviews, EarlyView.
ABSTRACT Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low‐grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity‐related health conditions.
Paulo José Basso, Alejandro Schcolnik‐Cabrera, Mengyi Zhu, Erin Strachan, Xavier Clemente‐Casares, Sue Tsai   +5 more
wiley   +1 more source

The skeletal muscle–adipose creatine metabolic axis: A novel paradigm for lipid metabolism reprogramming and obesity management

Experimental Physiology, EarlyView.
Abstract The global prevalence of obesity and related metabolic disorders has spurred interdisciplinary research to develop new intervention strategies. Current research is increasingly focusing on the exercise‐induced browning of white adipose tissue and the mechanisms by which it improves energy metabolism.
Yuhui Su, Na Liu, Yang Liu, Yiqun Sun, Yike Jiao   +4 more
wiley   +1 more source

Creatine kinase B mediates UCP1-independent beige fat thermogenesis via the futile creatine cycle in mice

Molecular Metabolism
Objectives: Creatine kinase B (CKB) is the main isoenzyme driving creatine kinase (CK) activity in classical brown adipocytes. However, the specific CK isoenzyme active in beige adipocytes remains unknown.
Jakub Bunk, Mina Ersin, Mohammed F. Hussain, Bozena Samborska, Maria Guerra-Martinez, Drishti Soni, Lawrence Kazak   +6 more
doaj   +1 more source

Silver nanoparticles inhibit beige fat function and promote adiposity

Molecular Metabolism, 2019
Objective: Obesity is a complex chronic disease of high prevalence worldwide. Multiple factors play integral roles in obesity development, with rising interest focusing on the contribution of environmental pollutants frequent in modern society.
Lishu Yue, Wenjun Zhao, Dongmei Wang, Meiyao Meng, Ying Zheng, Yu Li, Jin Qiu, Jian Yu, Yang Yan, Peng Lu, Youmin Sun, Jie Fu, Jiqiu Wang, Qiang Zhang, Lingyan Xu, Xinran Ma   +15 more
doaj   +1 more source

Perivascular adipose tissue inflammation in vascular disease [PDF]

, 2017
Perivascular adipose tissue (PVAT) plays a critical role in the pathogenesis of cardiovascular disease. In vascular pathologies, perivascular adipose tissue increases in volume and becomes dysfunctional, with altered cellular composition and molecular ...
Guzik, Tomasz J., Nosalski, Ryszard
core   +1 more source

Early adversity and the comorbidity between metabolic disease and psychopathology

The Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas, Patricia Pelufo Silveira   +1 more
wiley   +1 more source

Cold adaptation in pigs depends on UCP3 in beige adipocytes [PDF]

Journal of Molecular Cell Biology, 2017
Pigs lack functional uncoupling protein 1 (UCP1) making them susceptible to cold. Nevertheless, several pig breeds are known to be cold resistant. The molecular mechanism(s) enabling such adaptation are currently unknown. Here, we show that this resistance is not dependent on shivering, but rather depends on UCP3 and white adipose tissue (WAT) browning.
Jun Lin, Chunwei Cao, Cong Tao, Rongcai Ye, Meng Dong, Qiantao Zheng, Chao Wang, Xiaoxiao Jiang, Guosong Qin, Changguo Yan, Kui Li, John R Speakman, Yanfang Wang, Wanzhu Jin, Jianguo Zhao   +14 more
openaire   +3 more sources

Brown adipose tissue activity impacts systemic lactate clearance in male mice

The Journal of Physiology, EarlyView.
Abstract figure legend Using lactate tolerance tests and in vivo 13C isotopic tracing experiments performed in male mice housed at different temperatures, this study demonstrates that the state of activation of non‐shivering thermogenesis in brown adipose tissue (BAT) impacts systemic lactate metabolism.
Rémi Montané, Yannick Jeanson, Damien Lagarde, Spiro Khoury, Léana Porcher‐Bibes, Jean Nakhle, Marie Sallese, Mélissa Parny, Isabelle Raymond‐Letron, Emma Huard, Raphael Alves de Souza, Anne Galinier, Luc Pellerin, Anne‐Karine Bouzier Sore, Jean‐Philippe Pradère, Cédric Moro, Louis Casteilla, Armelle Yart, Cédric Dray, Jean‐Charles Portais, Isabelle Ader, Audrey Carriere   +21 more
wiley   +1 more source

Stepping Up Human Beige Fat Cell Production

Cell Reports, 2018
Beige fat cells hold significant promise for reducing obesity and metabolic disease. Su et al. (2018) present a robust method to produce human beige adipocytes from pluripotent stem cells via the generation of an expandable intermediary population of ...
Wenli Yang, Patrick Seale
doaj   +1 more source