Bioengineering Beige Adipose Tissue Therapeutics [PDF]
Frontiers in Endocrinology, 2015 Unlocking the therapeutic potential of brown/beige adipose tissue requires technological advancements that enable the controlled expansion of this uniquely thermogenic tissue.
K. Tharp, A. Stahl
semanticscholar +6 more sources
Maintaining mitochondria in beige adipose tissue [PDF]
Adipocyte, 2019 Individual cell types vary enormously in the amount of different organelles they contain. One such organelle is the mitochondrion. Understanding how mitochondrial levels are controlled is essential since so many disease states seem to involve ...
Xiaodan Lu
semanticscholar +5 more sources
The Gq signalling pathway inhibits brown and beige adipose tissue [PDF]
Nature Communications, 2016 Brown adipose tissue (BAT) dissipates nutritional energy as heat via the uncoupling protein-1 (UCP1) and BAT activity correlates with leanness in human adults.
Thorsten Gnad +2 more
exaly +8 more sources
Beige Adipose Tissue Identification and Marker Specificity—Overview [PDF]
Frontiers in Endocrinology, 2021 Adipose tissue (AT) is classified based on its location, physiological and functional characteristics. Although there is a clear demarcation of anatomical and molecular features specific to white (WAT) and brown adipose tissue (BAT), the factors that ...
Anna-Claire Pilkington +2 more
semanticscholar +5 more sources
Brown and Beige Adipose Tissue [PDF]
Endocrinology and Metabolism Clinics of North America, 2016 Anny Mulya, John P. Kirwan
semanticscholar +4 more sources
Do Bariatric Surgeries Enhance Brown/Beige Adipose Tissue Thermogenesis? [PDF]
Frontiers in Endocrinology, 2020 Bariatric surgeries induce marked and durable weight loss in individuals with morbid obesity through powerful effects on both food intake and energy expenditure.
M. Hankir, F. Seyfried
semanticscholar +6 more sources
Matrix-Assisted Transplantation of Functional Beige Adipose Tissue [PDF]
Diabetes, 2015 Novel, clinically relevant, approaches to shift energy balance are urgently needed to combat metabolic disorders such as obesity and diabetes. One promising approach has been the expansion of brown adipose tissues that express uncoupling protein (UCP) 1 ...
K. Tharp +8 more
semanticscholar +6 more sources
An update on the secretory functions of brown, white, and beige adipose tissue: Towards therapeutic applications [PDF]
Rev Endocr Metab Disord, 2023 Adipose tissue, including white adipose tissue (WAT), brown adipose tissue (BAT), and beige adipose tissue, is vital in modulating whole-body energy metabolism. While WAT primarily stores energy, BAT dissipates energy as heat for thermoregulation.
Zeinab Ghesmati +5 more
semanticscholar +2 more sources
Brown and beige adipose tissue: a novel therapeutic strategy for obesity and type 2 diabetes mellitus [PDF]
Adipocyte, 2021 Mammalian adipose tissue can be divided into two major types, namely, white adipose tissue (WAT) and brown adipose tissue (BAT). According to classical view, the main function of WAT is to store excess energy in the form of triglycerides, while BAT is a ...
Long Cheng +13 more
semanticscholar +2 more sources
Direct lentivirus injection for fast and efficient gene transfer into brown and beige adipose tissue [PDF]
J Biol Methods, 2016 Brown adipose tissue is a special type of fat contributing to energy expenditure in human newborns and adults. Moreover, subcutaneous white adipose tissue has a high capacity to adapt an energy-consuming, brown-like/beige phenotype. Here, we developed an
Aileen Balkow +6 more
semanticscholar +4 more sources