Brown adipocytes can display a mammary basal myoepithelial cell phenotype in vivo [PDF]
, 2017 This work was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB13030000) and the CAS-Novonordisk Foundation, as well as grants from the ‘1000 talents’ recruitment program, and a ‘Great-wall professorship’ from ...
Jin, Wanzhu +8 more
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Nature Communications, 2023 Thermogenic beige fat can reduce fat mass and improve metabolic health, yet the ability to form beige fat rapidly declines with age. Here, the authors show that targeting the age-related ramping of Pdgfrβ signalling restores the ageing adipose tissue ...
Abigail M. Benvie +5 more
doaj +1 more source
Thermogenic adipose tissue in energy regulation and metabolic health
Frontiers in Endocrinology, 2023 The ability to generate thermogenic fat could be a targeted therapy to thwart obesity and improve metabolic health. Brown and beige adipocytes are two types of thermogenic fat cells that regulate energy balance. Both adipocytes share common morphological,
Siwen Xue, Derek Lee, Daniel C. Berry
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An easy method for the clear detection of beige fat UCP1 by Western blotting. [PDF]
Adipocyte, 2019 Park MJ, Lee CM, Kim DI.
europepmc +3 more sources
Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells. [PDF]
Cancer Metab, 2020 Kawashima M +12 more
europepmc +3 more sources
Intra-abdominal adipose tissue of laboratory mice adapted to different temperature regimes [PDF]
, 2018 For the first time the presence of beige adipocytes, cellularity, basic metabolic parameters of perigonadal abdominal fat have studied in autbred laboratory mice kept at different temperature regimes: 1) 30°С (thermoneutral zone) and 2) regular daily 8 ...
Якуненков, А. В.
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Functional and Genetic Characterization of Porcine Beige Adipocytes
Cells, 2022 Beige adipocytes are a distinct type of fat cells with a thermogenic activity that have gained substantial attention as an alternative cellular anti-obesity target in humans.
Lilan Zhang +9 more
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Combating Obesity With Thermogenic Fat: Current Challenges and Advancements
Frontiers in Endocrinology, 2020 Brown fat and beige fat are known as thermogenic fat due to their contribution to non-shivering thermogenesis in mammals following cold stimulation. Beige fat is unique due to its origin and its development in white fat.
Ruping Pan +3 more
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TGF-β receptor 1 regulates progenitors that promote browning of white fat
Molecular Metabolism, 2018 Objective: Beige/brite adipose tissue displays morphological characteristics and beneficial metabolic traits of brown adipose tissue. Previously, we showed that TGF-β signaling regulates the browning of white adipose tissue. Here, we inquired whether TGF-
Umesh D. Wankhade +10 more
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Transcriptional Control of Brown and Beige Fat Development and Function. [PDF]
Obesity (Silver Spring), 2019 Adipose tissue, once viewed as an inert organ of energy storage, is now appreciated to be a central node for the dynamic regulation of systemic metabolism. There are three general types of adipose tissue: white, brown, and brown‐in‐white or “beige” fat.
Shapira SN, Seale P.
europepmc +4 more sources