Results 51 to 60 of about 314,272 (255)
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
The genus Serratia harbors opportunistic pathogenic species, among which Serratia marcescens is pathogenic for honeybees although little studied. Recently, virulent strains of S.
Chiara Braglia +11 more
doaj +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Leatherleaf fern (Rumohra adiantiformis) is a famous ornamental-leaf plant that has been used by florist entrepreneurs around the world. It is one of the leading export commodities in Indonesia, however, currently, there are some diseases of this leaf ...
Barokati Tsaniyah +2 more
doaj +1 more source
Abies nordmanniana is an economically important tree crop widely used for Christmas tree production. After initial growth in nurseries, seedlings are transplanted to the field.
Adriana M. Garcia-Lemos +7 more
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
The role of biofertilizers in improving vegetative growth, yield and fruit quality of apple
Apple trees which grafted on M.M. 106 stocks were planted at the beginning of spring 2014 in pots at the Research Institute of Horticulture in Skierniewice, Poland.
Walid Fediala Abd El-Gleel Mosa +5 more
doaj +1 more source
Probiotics: The Beneficial Bacteria For Human Health
Probiotics are living bacteria that are good for our health, especially our digestive system. They are frequently referred to as "good bacteria" since they contribute to the maintenance of a healthy balance of microorganisms in our gut. Probiotics have been known for centuries, although the term "probiotic" was coined in the twentieth century.
openaire +1 more source

