Results 51 to 60 of about 25,772 (306)

Synthesis and Analgesic Activity of Novel Derivatives of 1,2-Substituted Benzimidazoles

open access: yesJournal of Chemistry, 2013
A series of novel 2-phenylhydrazinomethyl and 2-(2-hydroxyphenyl)-benzimidazole derivatives substituted at the N1-position of benzimidazole nucleus were synthesized as well as screened for analgesic activity.
Shobhit Srivastava   +3 more
doaj   +1 more source

Synthesis, biological investigation, and docking studies of benzimidazole derivatives as butyrylcholinesterase and acetylcholinesterase inhibitors [PDF]

open access: yesشیمی کاربردی روز
The cholinergic hypothesis is one of the hypotheses of Alzheimer's disease that shows the relationship between the onset and progression of the disease. One of the main ways to increase the level of acetylcholine is to inhibit cholinesterase enzymes. The
Maryam Rouhi   +2 more
doaj   +1 more source

Benzimidazole derivatives endowed with potent antileishmanial activity [PDF]

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2017
Two sets of benzimidazole derivatives were synthesised and tested in vitro for activity against promastigotes of Leishmania tropica and L. infantum. Most of the tested compounds resulted active against both Leishmania species, with IC50 values in the low micromolar/sub-micromolar range.
Tonelli, Michele   +8 more
openaire   +6 more sources

Trimerization of aromatic nitriles [PDF]

open access: yes, 1977
Triazine compounds and cross-linked polymer compositions were made by heating aromatic nitriles to a temperature in the range of about 100 C to about 700 C, in the presence of a catalyst or mixture of catalysts.
Hsu, L. C.
core   +1 more source

Unexpected N-C bond fission of fused N-alkylbenzimidazolium salts. A new approach to pyrido[1,2-a]- or pyridazino[1,6-a]benzimidazoles [PDF]

open access: yes, 1998
The reaction of N-carboxymethylpyrido[1,2-a]- and pyridazino[1,6-a]benzimidazolium salts with thionyl chloride resulted in an N-C bond fission, yielding the corresponding pyrido[1,2-a]- and pyridazino[1,6-a]benzimidazoles.
García Navío, José Luis   +4 more
core   +3 more sources

Atomically Precise Ruddlesden–Popper Faults Induced Enhanced Emission in Ligand Stabilized Mixed Halide Perovskites

open access: yesAdvanced Materials, EarlyView.
This study overcomes challenges in visualizing atomic‐level defects in perovskite nanocrystals, promising to significantly improve the stability and performance of quantum dot‐based light‐emitting devices. Using double‐Cs‐corrected transmission electron microscopy, the study enables atomic‐resolution imaging of elusive RuddlesdenPopper faults hidden ...
Somnath Mahato   +6 more
wiley   +1 more source

Biocatalytic Alkylation of Ambident Nucleophiles Enables Selective N‐Functionalization of Heterocycles and Late‐Stage Modifications

open access: yesAngewandte Chemie, EarlyView.
N‐alkylated heteroarenes are key structural motifs in bioactive compounds, but their regioselective synthesis via coupling of readily available azoles with haloalkanes remains very challenging. Here, we present a mild biocatalytic approach that proceeds on gram‐scale, is highly chemo‐ and regioselective, offering rapid access to valuable N‐alkylated ...
Felipe Ospina   +10 more
wiley   +2 more sources

Molecular Nanoarchitectonic Sensing Layer for Analysis of Volatile Fatty Acids in Bioreactor Headspaces Using a Nanomechanical Sensor

open access: yesAdvanced Materials Technologies, EarlyView.
A porous crystalline sensing layer has been developed in conjunction with a nanomechanical sensor for the sensitive detection of volatile fatty acids (VFAs) in admixture at high relative humidity. The sensitive, selective sensor based on supramolecular design improves the economic viability of anaerobic digesters toward a carbon neutral society ...
Subrata Maji   +13 more
wiley   +1 more source

Isotope Engineering of Tetraphenylethylene: Aggregate‐Dependent Enhancement of Luminescence Efficiency

open access: yesAngewandte Chemie, EarlyView.
In loosely packed nanoaggregates, increased deuteration enhances photoluminescence quantum yields (PLQY) and extends the fluorescence lifetimes of tetraphenylethylene (TPE) by reducing internal conversion rates. Conversely, in tightly packed crystalline states, deuteration leads to decreased PLQY and shortened lifetimes, attributable to the Duschinsky ...
Siwei Zhang   +11 more
wiley   +2 more sources

Skin Damages—Structure Activity Relationship of Benzimidazole Derivatives Bearing a 5-Membered Ring System

open access: yesMolecules, 2020
In the search for scaffolds for multifunctional compounds we investigated the structure activity relationship of a class of benzimidazole derivatives bearing 5-membered ring.
Ernestine Nicaise Djuidje   +8 more
doaj   +1 more source

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