Results 61 to 70 of about 40,476 (314)
Benzimidazoles Downregulate Mdm2 and MdmX and Activate p53 in MdmX Overexpressing Tumor Cells
Molecules, 2019 Tumor suppressor p53 is mutated in about 50% of cancers. Most malignant melanomas carry wild-type p53, but p53 activity is often inhibited due to overexpression of its negative regulators Mdm2 or MdmX.
Zuzana Mrkvová +4 more
doaj +1 more source
The effect of lipophilicity on the antibacterial activity of some 1-benzylbenzimidazole derivatives [PDF]
, 2008 In the present paper, the antibacterial activity of some 1-benzylbenzimidazole derivatives were evaluated against the Gram-negative bacteria Escherichia coli. The minimum inhibitory concentration was determined for all the compounds.
D. D. CVETKOVIC +2 more
core +1 more source
Advanced Materials Technologies, EarlyView.A porous crystalline sensing layer has been developed in conjunction with a nanomechanical sensor for the sensitive detection of volatile fatty acids (VFAs) in admixture at high relative humidity. The sensitive, selective sensor based on supramolecular design improves the economic viability of anaerobic digesters toward a carbon neutral society ...
Subrata Maji +13 more
wiley +1 more source
A brief review on the mode of action of antinematodal drugs
Acta Veterinaria, 2017 Anthelmintics are some of the most widely used drugs in veterinary medicine. Here we review the mechanism of action of these compounds on nematode parasites.
Abongwa Melanie +2 more
doaj +1 more source
Química Nova, 2007 The aim of this work was to develop and validate an analytical methodology for simultaneous determination of mebendazole and thiabendazole, two benzimidazoles used as anthelmintics.
Núbia K. de Paula, Marcelo M. Sena
doaj +1 more source
Quantitative structure-activity relationship of some 1-benzylbenzimidazole derivatives as antifungal agents [PDF]
, 2007 In the present study, the antifungal activity of some 1-benzylbenzimidazole derivatives against yeast Saccharomyces cerevisiae was investigated. The tested benzimidazoles displayed in vitro antifungal activity and minimum inhibitory concentration (MIC ...
Barna Dijana J. +2 more
core +1 more source
Influence of Outcoupling Layers on Top‐Emitting Perovskite Light‐Emitting Diodes
Advanced Optical Materials, Volume 13, Issue 8, March 13, 2025.Top‐emitting perovskite LEDs offer benefits over typical bottom‐emitting architectures, toward lasing, improved thermal management, and on‐chip fabrication compatibility. Outcoupling layers offer a strategy uniquely applicable to top‐emitting LEDs to optimize EQE by improving optical outcoupling.
James C. Loy +5 more
wiley +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2017 Cancer stem cells (CSCs) have been objects of intensive study since their identification in 1994. Adopting a structural rigidification approach, a novel series of 3-phenylthiazolo[3,2-a]benzimidazoles 4a–d was designed and synthesised, in an attempt to ...
Ghada H. Al-Ansary +8 more
doaj +1 more source
Azole Compounds as Inhibitors of Candida albicans: QSAR Modelling
Frontiers in Chemistry, 2021 Candida albicans is a pathogenic opportunistic yeast found in the human gut flora. It may also live outside of the human body, causing diseases ranging from minor to deadly. Candida albicans begins as a budding yeast that can become hyphae in response to
Davood Gheidari +2 more
doaj +1 more source
Advanced Sustainable Systems, EarlyView.This study explores polyoxometalate‐based hybrids with varying dimensionalities, linking molecular, polymeric, and framework structures to supercapacitor performance. The results highlight how structural tuning enhances surface area, porosity, and charge transport, offering insights into designing efficient energy storage materials.
Daria Nowicka +6 more
wiley +1 more source