GABAA receptor subtypes and benzodiazepine use, misuse, and abuse
Frontiers in Psychiatry, 2023 Benzodiazepines have been in use for over half a century. While they remain highly prescribed, their unfavorable side-effect profile and abuse liability motivated a search for alternatives.
Elif Engin, Elif Engin
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ELISA detection of phenazepam, etizolam, pyrazolam, flubromazepam, diclazepam and delorazepam in blood using Immunalysis® benzodiazepine kit [PDF]
Journal of Analytical Toxicology, 2015 Phenazepam and etizolam were the first uncontrolled benzodiazepines available for sale in the UK. Pyrazolam, flubromazepam and diclazepam are not used medicinally anywhere in the world; they are produced exclusively for the uncontrolled, recreational ...
Mckeown, Denise A. +2 more
core +3 more sources
Long-term consequences of benzodiazepine-induced neurological dysfunction: A survey
PLoS ONE, 2023 Background Acute benzodiazepine withdrawal has been described, but literature regarding the benzodiazepine-induced neurological injury that may result in enduring symptoms and life consequences is scant.
Alexis D. Ritvo +5 more
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Patterns of benzodiazepine underdosing in the Established Status Epilepticus Treatment Trial
Epilepsia, 2021 This study was undertaken to describe patterns of benzodiazepine use as first‐line treatment of status epilepticus (SE) and test the association of benzodiazepine doses with response to second‐line agents in patients enrolled in the Established Status ...
A. Sathe +14 more
semanticscholar +1 more source
Health Expectations, 2022 Introduction Long‐term benzodiazepine receptor agonist (BZRA) use persists in healthcare settings worldwide and poses risks of patient harm. Objective This study aimed to develop an intervention to support discontinuation of long‐term BZRA use among ...
Tom Lynch +8 more
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Comparison of Nitrous Oxide-Oxygen as Inhalation Agent, Midazolam, Ketamine alone and in Combination as Oral Sedative Agents for In-office Paediatric PatientsA Randomised Control Trial [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: In-office pharmacological sedation techniques are best applied to manage an extremely fearful preschooler, especially during primary dentition or a child’s early mixed dentition period.
MONIKA NAGPAL +4 more
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Benzodiazepine Misuse: An Epidemic Within a Pandemic
Cureus, 2021 Coronavirus disease 2019 (COVID-19) had deleterious effects on patients with mental health problems and several studies have shown a spike in the rates of depression, insomnia, and post-traumatic stress disorder.
A. Sarangi, T. Mcmahon, J. Gude
semanticscholar +1 more source
Exploring trends in benzodiazepine-positive fatal drug overdoses in Tennessee, 2019–2021
Annals of Medicine, 2023 Background Benzodiazepine-positive overdoses increased between 2019 and 2021 in Tennessee. We sought to determine the changes in the number and characteristics of prescription and illicit benzodiazepine-positive fatal drug overdoses during this period ...
Jenna Moses +2 more
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A review on the chemistry and pharmacological properties of benzodiazepine motifs in drug design
Arab Journal of Basic and Applied Sciences, 2022 Benzodiazepines are an important class of heterocyclic compounds in organic chemistry. They are known for their diverse physicochemical and biological properties.
Olayinka O. Tolu-Bolaji +3 more
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