Results 41 to 50 of about 174,536 (299)
The Impact of Opioid Prescribing Limits on Drug Usage in South Carolina: A Novel Geospatial and Time Series Data Analysis [PDF]
arXiv, 2023 Background: To curb the opioid epidemic, legislation regulating the amount of opioid prescriptions covered by Medicaid (Title XIX of the Social Security Act Medical Assistance Program) came into effect in May 2018 in South Carolina. Methods: We employ a classification system based on distance and disparity between dispensers, prescribers, and patients ...
arxiv
Scandinavian Journal of Primary Health Care, 2017 Objective: To compare how newly initiated treatment with benzodiazepines, Z-hypnotics or both associates with the reception of disability pension among 40,661 individuals of a working age. Design: Prescription register study.
Ingunn F. Tvete +2 more
doaj +1 more source
ODD: A Benchmark Dataset for the Natural Language Processing based Opioid Related Aberrant Behavior Detection [PDF]
arXiv, 2023 Opioid related aberrant behaviors (ORABs) present novel risk factors for opioid overdose. This paper introduces a novel biomedical natural language processing benchmark dataset named ODD, for ORAB Detection Dataset. ODD is an expert-annotated dataset designed to identify ORABs from patients' EHR notes and classify them into nine categories; 1 ...
arxiv
A TSPO ligand is protective in a mouse model of multiple sclerosis. [PDF]
, 2013 Local production of neurosteroids such as progesterone and allopregnanolone confers neuroprotection in central nervous system (CNS) inflammatory diseases.
Chechneva, Olga V +5 more
core +2 more sources
British medical journal, 2016 Objective To determine whether higher cumulative use of benzodiazepines is associated with a higher risk of dementia or more rapid cognitive decline. Design Prospective population based cohort.
S. Gray +7 more
semanticscholar +1 more source
Journal of Clinical Psychiatry, 2018 OBJECTIVE Although benzodiazepine misuse and use disorders are associated with adverse health effects, it is unknown what proportion of benzodiazepine users misuse them or meet criteria for benzodiazepine use disorders.
C. Blanco +4 more
semanticscholar +1 more source
Potentially inappropriate prescribing in nursing home residents detected with the community pharmacist specific GheOP3S-tool [PDF]
, 2016 Background: The Ghent Older People’s Prescriptions community Pharmacy Screening (GheOP3S-)tool was recently developed to screen for potentially inappropriate prescribing (PIP).
Boussery, Koen +7 more
core +1 more source
(4E)-1-Decyl-4-(2-oxopropylidene)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one
IUCrData, 2016 The title compound, C22H32N2O2, forms bilayers with the n-decyl chains in extended conformation oriented towards the interior of the bilayer structure. Weak C—H...O interactions help to stabilize the exterior surfaces.
Jihad Sebhaoui +4 more
doaj +1 more source
TSPO interacts with VDAC1 and triggers a ROS-mediated inhibition of mitochondrial quality control [PDF]
, 2014 The 18-kDa TSPO (translocator protein) localizes on the outer mitochondrial membrane (OMM) and participates in cholesterol transport. Here, we report that TSPO inhibits mitochondrial autophagy downstream of the PINK1-PARK2 pathway, preventing essential ...
Anholt R +22 more
core +2 more sources
Discouraging Use of Benzodiazepines for Anxiety and Insomnia [PDF]
, 2018 Benzodiazepines are commonly prescribed for anxiety and insomnia because patients respond quickly to them. Although they are meant to be short-term solutions, patients often use them for more than ten years.
Tsao, Jackie
core +1 more source