Results 41 to 50 of about 138,894 (338)
JAMA Network Open, 2018 Key Points Question How does the risk of overdose change with the number of days with concurrent opioid and benzodiazepine use? Findings In this cohort study of US Medicare data, the overdose risk associated with concurrent benzodiazepine use changed ...
I. Hernandez +3 more
semanticscholar +1 more source
Scandinavian Journal of Primary Health Care, 2017 Objective: To compare how newly initiated treatment with benzodiazepines, Z-hypnotics or both associates with the reception of disability pension among 40,661 individuals of a working age. Design: Prescription register study.
Ingunn F. Tvete +2 more
doaj +1 more source
Current Perspective on the Location and Function of Gamma- Aminobutyric Acid (GABA) and its Metabolic Partners in the Kidney. [PDF]
, 2014 Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter located in the mammalian central nervous system, which binds to GABAA and GABAB receptors to mediate its neurological effects.
Dunn, Kadeshia +3 more
core +1 more source
TREC-Rio trial: a randomised controlled trial for rapid tranquillisation for agitated patients in emergency psychiatric rooms [ISRCTN44153243] [PDF]
, 2002 Agitated or violent patients constitute 10% of all emergency psychiatric treatment. Management guidelines, the preferred treatment of clinicians and clinical practice all differ.
A Jablensky +21 more
core +3 more sources
British medical journal, 2015 Objective To study the association between benzodiazepine prescribing patterns including dose, type, and dosing schedule and the risk of death from drug overdose among US veterans receiving opioid analgesics. Design Case-cohort study.
Tae Woo Park +4 more
semanticscholar +1 more source
Serotonin drives a novel GABAergic synaptic current recorded in rat cerebellar purkinje cells: a lugaro cell to Purkinje cell synapse [PDF]
, 2003 We recorded a novel fast GABAergic synaptic current in cerebellar Purkinje cells in rat brain slices using patch-clamp techniques. Because of a relatively low sensitivity to bicuculline, these currents can be recorded under conditions in which basket ...
Dean, I., Edwards, F.A., Robertson, S.J.
core +3 more sources
The Prevalence of Benzodiazepine Usage Among Cardiovascular Patients [PDF]
مجله علوم پزشکی صدراIntroduction: Both benzodiazepines and cardiovascular disease independently increase dementia risk, while anxiety and other psychiatric disorders may exacerbate cardiovascular diseases.
Vahid Mohammadkarimi +7 more
doaj +1 more source
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
(4E)-1-Decyl-4-(2-oxopropylidene)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one
IUCrData, 2016 The title compound, C22H32N2O2, forms bilayers with the n-decyl chains in extended conformation oriented towards the interior of the bilayer structure. Weak C—H...O interactions help to stabilize the exterior surfaces.
Jihad Sebhaoui +4 more
doaj +1 more source
Visualizing mitochondrial FoF1-ATP synthase as the target of the immunomodulatory drug Bz-423
, 2018 Targeting the mitochondrial enzyme FoF1-ATP synthase and modulating its catalytic activities with small molecules is a promising new approach for treatment of autoimmune diseases. The immuno-modulatory compound Bz-423 is such a drug that binds to subunit
Börsch, Michael +2 more
core +1 more source