Results 1 to 10 of about 211,779 (381)

Benzodiazepines: Their Use either as Essential Medicines or as Toxics Substances

Toxics, 2021
This review highlights the nature, characteristics, properties, pharmacological differences between different types of benzodiazepines, the mechanism of action in the central nervous system, and the degradation of benzodiazepines. In the end, the efforts
Edilma Sanabria, Ronald Edgardo Cuenca, Miguel Ángel Esteso, Mauricio Maldonado   +3 more
doaj   +2 more sources

The emergence of new psychoactive substance (NPS) benzodiazepines: a review [PDF]

Drug Testing and Analysis, 2017
The market for new psychoactive substances has increased markedly in recent years and there is now a steady stream of compounds appearing every year.
Ajir, Akerman, Anzillotti, Artemenko, Bachhuber, Barzaghi, Bergstrand, Bertilsson, Bertolino, Borea, Bourcier, Boxenbaum, Breimer, Broséus, Casacchiaa, Casellas, Childress, Chong, Coassolo, Court, Court, Crichton, Drummer, El Balkhi, El Balkhi, El Mahjoub, Famiglini, File, Fischer-Cornelssen, Fleishaker, Fleishaker, Fleishaker, Fracasso, Fraser, Fraser, Fukasawa, Fukasawa, GABAA, Garzone, Gavish, Gavish, Gerhards, Gitto, Goldstein, Greenblatt, Grobin, Haefely, Heikkinen, Heizmann, Hester, Holmes, Horváth, Huppertz, Høiseth, Inoue, Jones, Kapil, Kar, Katselou, Kerrigan, Kintz, Klotz, Kopanitsa, Krasowski, Kriikku, Kroboth, Lambert, Langley, Levine, Lim, Lomas, Lomas, Lukasik-Glebocka, Maddalena, Mandelli, Maskell, McAuleya, McClean, Megarbane, Meguro, Melo, Meyer, Mizuno, Moffat, Moosmann, Moosmann, Moosmann, Moosmann, Mozayani, Nakamae, Nakatsuka, O'Connor, O'Connor, Ochs, Oilman, Olivera, Olsen, Olsen, Olsen, Papadopoulos, Papadopoulos, Parmeggiani, Pellow, Pellow, Peng, Peppers, Persona, Pettersson Bergstrand, Pettersson Bergstrand, Rasanen, Robertson, Roman, Rundfeldt, Rupprecht, Rupprecht, Schwartz, Shearer, Sieghart, Sigel, Simonsen, Skopp, Skopp, Smith, Smith, Smith, So, Sohn, Sonne, Soriano, Stephenson, Sternbach, Tan, Tan, The Drug Enforcement Administration (DEA), Uddin, Usui, Venkatakrishnan, Vikingsson, Vogel, Wang, Westland, Whirl-Carrillo, Whitwam, Xu, Yegles, Zherdev, Zhu, Zhuk, Ékonomov, Чекулаев   +149 more
core   +4 more sources

Narrative Literature Review of Potential Atrial Fibrillation Mechanism of Action Induced by Discontinuation of Benzodiazepines

Acta Medica Lituanica, 2023
Introduction: Benzodiazepines are commonly prescribed but often misused, leading to dependence and withdrawal symptoms. Increased worldwide prescriptions raise adverse effects and overdose concerns, especially for the elderly.
Agnė Okulevičiūtė, Gabija Laubner Sakalauskienė   +1 more
doaj   +3 more sources

Impact of Medicare prescription drug (Part D) coverage expansion on utilisation and financial burden of benzodiazepines among older adults: an interrupted time series analysis

BMJ Open, 2021
Objective Benzodiazepines were excluded from Medicare Part D coverage since its introduction in 2006. Part D expanded coverage for benzodiazepines in 2013.
Minghui Li, Jing Yuan, Z Kevin Lu, Chelsea Dezfuli   +3 more
doaj   +1 more source

Shared structural mechanisms of general anesthetics and benzodiazepines

Nature, 2020
Most general anaesthetics and classical benzodiazepine drugs act through positive modulation of γ-aminobutyric acid type A (GABA A ) receptors to dampen neuronal activity in the brain 1 – 5 .
Jeong Joo Kim, A. Gharpure, J. Teng, Y. Zhuang, R. Howard, Shaotong Zhu, C. Noviello, R. M. Walsh, E. Lindahl, R. Hibbs   +9 more
semanticscholar   +2 more sources

Benzodiazepines: Uses, Dangers, and Clinical Considerations

Neurology International, 2021
Benzodiazepines (BZDs) are among one of the most widely prescribed drug classes in the United States. BZDs are a class of psychoactive drugs known for their depressant effect on the central nervous system (CNS).
Amber N. Edinoff, Catherine A. Nix, J. Hollier, C. Sagrera, Blake M Delacroix, Tunde Abubakar, E. Cornett, A. Kaye, A. Kaye   +8 more
semanticscholar   +1 more source

Trends in Nonfatal and Fatal Overdoses Involving Benzodiazepines — 38 States and the District of Columbia, 2019–2020

MMWR. Morbidity and mortality weekly report, 2021
Nonfatal and fatal drug overdoses increased overall from 2019 to 2020 (1).* Illicit benzodiazepines (e.g., etizolam, flualprazolam, and flubromazolam)† were increasingly detected among postmortem and clinical samples in 2020, often with opioids,§ and ...
Stephen J. Liu, J. O'Donnell, R. Gladden, Londell McGlone, Farnaz Chowdhury   +4 more
semanticscholar   +1 more source

Assessment of 2-Year Neurodevelopmental Outcomes in Extremely Preterm Infants Receiving Opioids and Benzodiazepines

JAMA Network Open, 2021
Key Points Question Is there an association between 2-year neurodevelopmental outcomes and use of opioids and/or benzodiazepines for sedation and analgesia in extremely preterm infants?
Mihai Puia-Dumitrescu, B. Comstock, Sijia Li, P. Heagerty, Krystle M. Perez, Janessa B. Law, T. Wood, S. Gogcu, D. Mayock, S. Juul   +9 more
semanticscholar   +1 more source

Deprescribing zolpidem reduces falls and fractures in patients with cirrhosis

JHEP Reports, 2022
Background & Aims: Benzodiazepines are associated with an increased risk of harm in patients with cirrhosis. However, stopping benzodiazepines must be done with care to avoid withdrawal or other unintended consequences. The impact of deprescribing on
Elliot B. Tapper, Zhe Zhao, G. Scott Winder, Neehar D. Parikh   +3 more
doaj   +1 more source

Pattern of utilization of benzodiazepines in patients with hypertension: A pilot study [PDF]

Vojnosanitetski Pregled, 2006
Background/Aim. The analysis of drug prescribing in general practice in Serbia showed that the use of benzodiazepines is most frequently associated with hypertension.
Divac Nevena, Veljković Slavomir, Nešić Zorica, Stojanović Radan, Bajčetić Milica, Vasiljević Zorana, Prostran Milica, Samardžić Ranka   +7 more
doaj   +1 more source