Results 11 to 20 of about 1,553 (193)

Synthesis and In Vitro Antileishmanial Efficacy of Novel Ethylene Glycol Analogues of Benzothiadiazine-1,1-dioxide. [PDF]

open access: hybridChem Biodivers
Abstract Leishmaniasis is a vector‐borne, parasitic disease affecting millions of people and animals worldwide. Current therapeutic options have proven to be ineffective in both treating the disease and preventing its spread. As a result, new drugs must be developed to effectively combat this disease.
Henning N   +5 more
europepmc   +4 more sources

Insulinoma in a dog ( Canis lupus familiaris ) with concurrent non‐cardiogenic pulmonary oedema [PDF]

open access: yesVeterinary Record Case Reports, Volume 13, Issue 4, December 2025.
A 12‐year‐old, female, neutered beagle presented with hypoglycaemia, sudden‐onset non‐ambulatory tetraparesis and a single tonic‐clonic seizure. Computed tomography revealed a pancreatic nodule, consistent with an insulinoma, an enlarged hepatic lymph ...
Dylan O’ Toole   +5 more
core   +3 more sources

New derivatives of 1,2,4-benzothiadiazines and their coordination chemistry [PDF]

open access: green, 2018
Chapter 1 provides an introduction to coordination chemistry and polydentate N-donor ligands along with a synopsis of heterocycles with N and S/N donor atoms.
Konstantina Pringouri
openalex   +3 more sources

Virtual screening for NS5B inhibitors of Hepatitis C virus [PDF]

open access: yes, 2012
Hepatitis C Virus (HCV) infection is a serious cause of chronic liver disease worldwide with more than 170 million infected individuals at a risk of developing significant morbidity and mortality.
Achuthsankar S. Nair   +2 more
core   +5 more sources

Synthesis and molecular docking studies of novel tricyclic and angular tetracyclic benzothiadiazines via sp3‐C‐H activation as potential colon cancer inhibitors

open access: yesJournal of Heterocyclic Chemistry, Volume 60, Issue 10, Page 1738-1759, October 2023., 2023
Substituted tricyclic and tetracyclic benzothiadiazines were synthesized in this paper, were synthesized via metal‐free intramolecular N‐iodosuccinimide (NIS)‐mediated radical oxidative sp3‐C‐H activation aminative cyclization. Docking studies of the tricyclic and angular tetracyclic 1,2,4‐benzothiadizine dioxides 26–34 and intermediates were carried ...
Sherif O. Kolade   +7 more
wiley   +1 more source

A Copper‐Catalyzed Interrupted Domino Reaction for the Synthesis of Fused Triazolyl Benzothiadiazine‐1‐oxides

open access: yesChemistry – A European Journal, Volume 29, Issue 13, March 1, 2023., 2023
A copper(I)‐catalyzed interrupted domino reaction of 2‐azido sulfoximines with 1‐iodoalkynes affords fused triazolyl‐containing benzothiadiazine‐1‐oxides in good to excellent yields. The substrate scope is broad and the functional group tolerance high.
Renè Hommelsheim   +6 more
wiley   +1 more source

Chemometric Methods for Simultaneous Determination of Candesartan Cilexetil and Hydrochlorothiazide in Binary Combinations

open access: yesJournal of Analytical Methods in Chemistry, Volume 2023, Issue 1, 2023., 2023
Simple, accurate, precise, and cost‐effective chemometric techniques for the measurement of candesartan cilexetil and hydrochlorothiazide in synthetic mixtures were improved and validated. H‐point standard addition, Q‐absorption ratio, and correction absorbance spectrophotometric techniques were utilized for the simultaneous determination of both ...
Diyar Salahuddin Ali   +1 more
wiley   +1 more source

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