Results 11 to 20 of about 2,430 (167)

The Antihypertensive Actions of Benzothiadiazines [PDF]

Circulation, 1961
Bertram M. Winer
semanticscholar   +6 more sources

Synthesis and molecular docking studies of novel tricyclic and angular tetracyclic benzothiadiazines via sp³‐C‐Hactivation as potential colon cancer inhibitors [PDF]

Journal of Heterocyclic Chemistry, 2023
This paper describes the synthesis of tricyclic and tetracyclic benzothiadiazines and their derivatives, which are known for their versatility as bioactive agents.
S.O. Kolade, Oluwafemi S. Aina, Allen T. Gordon, Eric C. Hosten, Idris A. Olasupo, Adeniyi S. Ogunlaja, Olayinka T. Asekun, Oluwole B. Familoni   +7 more
openalex   +2 more sources

Clinical and Physiological Implications of Diabetes Induced by Benzothiadiazines [PDF]

Diabetes, 1964
Frederick Wolff
semanticscholar   +5 more sources

PHOTOINDUCED INTRAMOLECULAR C–N COUPLING FOR THE SYNTHESIS OF AZOLO[1,2,4]BENZOTHIADIAZINES DERIVATIVES [PDF]

Annalen der Pharmacie
: This paper explores an original synthesis of novel heterocyclic compounds derived from photoinduced intramolecular coupling reactions, involving the formation of C‐N and C‐C bonds.
Eibber J. García-Manzano, Micaela A. Cuellar, Sandra E. Martı́n, María E. Budén, Silvia M. Barolo   +4 more
openalex   +2 more sources

COMBINATORIAL PHARMACOPHORE MODELING AND ATOM BASED 3D QSAR STUDIES OF BENZOTHIADIAZINES AS HCV-NS5B INHIBITORS

, 2018
Objective: The objective of the current study was to elucidate the 3D pharmacophoric features of benzothiadiazine derivatives that are crucial for inhibiting Hepatitis C virus (HCV) Non-structural protein 5B (NS5B) and quantifying the features by ...
Prasanthi Polamreddy, Vinita Vishwakarma, Manoj Kumar Mahto   +2 more
openalex   +3 more sources

A cell-based assay for RNA synthesis by the HCV polymerase reveals new insights on mechanism of polymerase inhibitors and modulation by NS5A. [PDF]

PLoS One, 2011
RNA synthesis by the genotype 1b hepatitis C virus (HCV) polymerase (NS5B) transiently expressed in Human embryonic kidney 293T cells or liver hepatocytes was found to robustly stimulate RIG-I-dependent luciferase production from the interferon β ...
Ranjith-Kumar CT, Wen Y, Baxter N, Bhardwaj K, Cheng Kao C.   +4 more
europepmc   +2 more sources

Corrigendum to “Integrated structure-based activity prediction model of benzothiadiazines on various genotypes of HCV NS5b polymerase (1a, 1b and 4) and its application in the discovery of new derivatives” [Bioorg. Med. Chem. 20(7) (2012) 2455–2478]

, 2013
Mohamed A.H. Ismail, Dalal A. Abou El Ella, Khaled A. M. Abouzid, Amr H. Mahmoud   +3 more
openalex   +2 more sources

Synthesis and characterisation of first row transition metal complexes of functionalized 1,2,4-benzothiadiazines.

Dalton Transactions, 2014
Reaction of the novel ligand 3-(2'-pyridyl)-benzo-1,2,4-thiadiazine (L) with the transition metal chloride salts MCl2·xH2O (M(II) = Mn, Fe, Co, Cu and Zn) in a 2 : 1 mole ratio afforded the mononuclear octahedral (high spin) complexes L2MCl2 (1a-1e ...
Ewan R. Clark, M. Anwar, B. Leontowicz, Yassine Beldjoudi, J. Hayward, W. Chan, E. L. Gavey, M. Pilkington, E. Zysman‐Colman, J. Rawson   +9 more
semanticscholar   +1 more source

Aryl Alkanehydrazonates and Their Thio Analogs. Synthesis of Some 2-Alkyl Derivatives of 4H-1,3,4-Benzoxadiazines and 4H-1,3,4-Benzothiadiazines

, 1977
Synthesis of some p-nitrophenyl alkanethiohydr azonates, RC(SC6H4NO2-p)=NNHC6H3BrNO2(2, 4−), and p-nitrophenyl alkanehydrazonates, RC(OC6H4NO2p=NNHC6H3BrNO2(2,4−) is described.
A. S. Shawali, H. Hassaneen
semanticscholar   +1 more source

Discovery of a Novel Benzothiadiazine-Based Selective Aldose Reductase Inhibitor as Potential Therapy for Diabetic Peripheral Neuropathy [PDF]

, 2023
Ruyi Jin, Jin Wang, Mingyue Li, Tian Tang, Yidong Feng, Sha Zhou, Honglei Xie, Haiyu Feng, Jianshuang Guo, Rui‐Jia Fu, Jiping Liu, Yuping Tang, Yajun Shi, Hui Guo, Yuwei Wang, Fayi Nie, Jing Li   +16 more
openalex   +2 more sources