Results 11 to 20 of about 3,633 (196)

3-Benzoyl-2-hydroxy-3a-[(3-methylquinoxalin-2-yl)methyl]-1H-pyrrolo[2,1-c][1,4]benzothiazine-1,4(3aH)-dione

Molbank, 2023
The reaction of 3-benzoylpyrrolo[2,1-c][1,4]benzothiazine-1,2,4-trione with 2,3-dimethylquinoxaline afforded 3-benzoyl-2-hydroxy-3a-[(3-methylquinoxalin-2-yl)methyl]-1H-pyrrolo[2,1-c][1,4]benzothiazine-1,4(3aH)-dione in a moderate yield. The compound was
Ekaterina A. Lystsova, Ekaterina E. Khramtsova   +1 more
doaj   +2 more sources

On the application of knoevenagel condensation for the synthesis of benzylidene benzothiazine compounds and structural study [PDF]

Química Nova, 2006
The synthesis and physico-chemical properties of new 6-acetylamino or 6-benzoyl-amino 2-benzylidene-4-methyl-4H-benzo[1,4]thiazin-3-ones and 6-benzoylamino or 6-nitro 2-benzylidene-4H-benzo[1,4]thiazin-3-ones are described.
Ana Maria Alves de Souza, Vera Lucia de Miranda Guarda, Lúcia Fernanda Cavalcanti da Costa Leite, José Maria Barbosa Filho, Maria do Carmo Alves de Lima, Suely Lins Galdino, Ivan da Rocha Pitta   +6 more
doaj   +6 more sources

Synthesis and Regularities of the Structure–Activity Relationship in a Series of N-Pyridyl-4-methyl-2,2-dioxo-1H-2λ⁶,1-benzothiazine-3-carboxamides

Scientia Pharmaceutica, 2019
According to our quantum and chemical calculations 4-methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxylic acid imidazolide is theoretically almost as reactive as its 2-carbonyl analog, and it forms the corresponding N-pyridyl-4-methyl-2,2-dioxo-1H-2&
Igor V. Ukrainets, Anna A. Burian, Ganna M. Hamza, Natali I. Voloshchuk, Oxana V. Malchenko, Svitlana V. Shishkina, Lyudmila V. Sidorenko, Kateryna O. Burian, Galina Sim   +8 more
doaj   +2 more sources

Structural Studies of 2-Pentyl/Pentenyl-Substituted Methyl 4-Hydroxy-2H-1,2-Benzothiazine-3-Carboxylate-1,1-Dioxide

Walailak Journal of Science and Technology, 2012
Crystal structures of methyl 2-pentyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylate-1,1-dioxide 1 and methyl 2-pentenyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylate-1,1-dioxide 2 have been determined after their synthesis from saccharin.
Muhammad Nadeem ARSHAD, Muhammad ZIA-UR-REHMAN, Islam Ullah KHAN, Ghulam MUSTAFA, Muhammad SHAFIQ, Hafiz Muhammad RAFIQUE, Kevin Travis HOLMAN   +6 more
doaj   +2 more sources

Crystal structure of 2-(4-methylphenyl)-4H-1,3-benzothiazine [PDF]

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C15H13NS, the thiazine ring adopts a boat conformation. The dihedral angle between the planes of the benzene ring of the benzothiazine unit and the tolyl ring is 19.52 (9)°.
N. C. Sandhya, Chandra, G. P. Suresha, N. K. Lokanath, M. Mahendra   +4 more
doaj   +2 more sources

Methyl 4-ethoxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide [PDF]

, 2008
Methyl 4-ethoxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1 ...
Muhammad Zia-ur-Rehman (7162790), Jamil Anwar Choudary (7163189), Mark R.J. Elsegood (4220665), N. Akbar (7163714), Hamid Latif Siddiqui (7162796)   +4 more
core   +5 more sources

High-Resolution Elemental Analysis of Neuromelanin-Containing Organelles in Human Locus Coeruleus. [PDF]

J Neurochem
Created in https://BioRender.com. Neuromelanin (NM), a dark metal‐chelating pigment in the brain, has long been of interest for its potential roles in aging and Parkinson's disease. In this study, we explored NM‐containing neurons (NM neurons) in the human locus coeruleus at unprecedented resolution.
Berro Z, Zucca FA, Subirana MA, Philippe AM, Schaumlöffel D, Carpentier A, Capucciati A, Bouvier D, Mittelbronn M, Audinot JN, Zecca L, Biesemeier A.   +11 more
europepmc   +2 more sources

Design, Synthesis, and Evaluation of Novel 2H-Benzo[b][1,4]thiazin-3(4H)-one Derivatives as New Acetylcholinesterase Inhibitors

Molecules, 2022
Alzheimer’s disease (AD) is a slowly progressive neurodegenerative disease that causes dementia in people aged 65 and over. In the present study, a series of thiadiazole hybrid compounds with benzothiazine derivatives as acetylcholinesterase inhibitors ...
Sazan Haji Ali, Derya Osmaniye, Begüm Nurpelin Sağlık, Serkan Levent, Yusuf Özkay, Zafer Asım Kaplancıklı   +5 more
doaj   +1 more source

Bioinspired Heterocyclic Partnership in a Cyanine-Type Acidichromic Chromophore

Molecules, 2020
A new red hair-inspired 1,4-benzothiazine-based scaffold is disclosed herein, built upon a modular D-π-A architecture via condensation of the easily accessible 3-phenyl-2H-1,4-benzothiazine with indole-3-carboxaldehyde.
Maria Laura Alfieri, Lucia Panzella, Marco d’Ischia, Alessandra Napolitano   +3 more
doaj   +1 more source

1,2-Benzothiazine Derivatives as Anti-HIV and Anti-HCV Agents: Structure-Activity Relationships and Research Perspectives. [PDF]

Int J Mol Sci
1,2-Benzothiazine derivatives have attracted attention as structurally versatile scaffolds for antiviral drug discovery. Their sulfur-containing heterocyclic core supports diverse substitution patterns, allowing modulation of physicochemical properties ...
Topolska I, Szczęśniak-Sięga BM.
europepmc   +2 more sources