Results 31 to 40 of about 3,633 (196)

2-[(2Z)-2-Benzylidene-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-4-yl]acetic acid

IUCrData, 2016
In the title compound, C17H13NO3S, the thiazine ring displays a screw-boat conformation. The dihedral angle between the terminal benzene ring and the mean plane of the 1,4-benzothiazine fused-ring system is 51.52 (6)°.
Nada Kheira Sebbar, Mohamed Ellouz, Joel T. Mague, Younes Ouzidan, El Mokhtar Essassi, Hafid Zouihri   +5 more
doaj   +1 more source

Synthesis, Structure, and Analgesic Properties of Halogen-Substituted 4-Hydroxy-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxanilides [PDF]

, 2016
As potential new analgesics, the corresponding 4-hydroxy-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxanilides have been obtained by amidation of ethyl 4-hydroxy-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxylate with aniline and its halogenated analogsin ...
Galina Sim, Olga Kryvanych, Lidiya Petrushova, Igor Ukrainets, Svitlana Shishkina, Lyudmila Sidorenko   +5 more
core   +2 more sources

Crystal structure of methyl 1-allyl-4-methyl-1H-benzo[c][1,2]thiazine-3-carboxylate 2,2-dioxide

Acta Crystallographica Section E: Crystallographic Communications, 2016
In the title compound, C14H15NO4S, the dihydrothiazine ring adopts a distorted sofa conformation with the S atom displaced from the mean plane through the N and C ring atoms by 0.767 (1) Å.
Liliana Azotla-Cruz, Svitlana Shishkina, Igor Ukrainets, Irina Lijanova, Natalya Likhanova   +4 more
doaj   +1 more source

(Z)-4-n-Butyl-2-(4-chlorobenzylidene)-2H-1,4-benzothiazin-3(4H)-one

IUCrData, 2017
In the title compound, C19H18ClNOS, the thiazin-3-one ring adopts a slightly distorted screw-boat conformation. An intramolecular C—H...S hydrogen bond encloses an S(6) ring and affects the overall conformation of the molecule. The dihedral angle between
Mohamed Ellouz, Nada Kheira Sebbar, Younes Ouzidan, Manpreet Kaur, El Mokhtar Essassi, Jerry P. Jasinski   +5 more
doaj   +1 more source

Synthesis, Crystal Structure, and Biological Activity of Ethyl 4-Methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxylate Polymorphic Forms

Scientia Pharmaceutica, 2018
Continuing the search for new potential analgesics among the derivatives of 4-methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxylic acid, the possibility of obtaining its esters by the alkylation of the corresponding sodium salt with iodoethane in ...
Igor V. Ukrainets, Anna A. Burian, Vyacheslav N. Baumer, Svitlana V. Shishkina, Lyudmila V. Sidorenko, Igor A. Tugaibei, Natali I. Voloshchuk, Pavlo S. Bondarenko   +7 more
doaj   +1 more source

Beyond Molecular Determinism: State‐Convergent Polymerization as a Functional Design Principle Under Chemical Complexity

Advanced Science, Volume 13, Issue 38, 9 July 2026.
This work introduces state‐convergent polymerization (SCP), a polymerization framework in which chemically diverse reaction pathways converge toward a reproducible functional polymeric state rather than a defined molecular structure. Using melanin and polydopamine as exemplars, SCP explains how robust polymer functions emerge under chemical and ...
Seonki Hong
wiley   +1 more source

Crystal structure, Hirshfeld surface analysis and interaction energy, DFT and antibacterial activity studies of (Z)-4-hexyl-2-(4-methylbenzylidene)-2H-benzo[b][1,4]thiazin-3(4H)-one

Acta Crystallographica Section E: Crystallographic Communications, 2020
The title compound, C22H25NOS, consists of methylbenzylidene and benzothiazine units linked to a hexyl moiety, where the thiazine ring adopts a screw-boat conformation.
Ghizlane Sebbar, Brahim Hni, Tuncer Hökelek, Joel T. Mague, Nada Kheira Sebbar, Bouchra Belkadi, El Mokhtar Essassi   +6 more
doaj   +1 more source

(Z)-2-Benzylidene-3-n-butoxy-2H-1,4-benzothiazine

IUCrData, 2017
In the title compound, C19H19NOS, the thiazin-3-one ring of the 1,4-thiazin-3-one moiety adopts a screw-boat conformation. The dihedral angle between the benzene rings is 31.0 (5)°. An intramolecular C—H...S hydrogen bond forms an S(6) ring motif. In the
Nada Kheira Sebbar, Mohamed Ellouz, Younes Ouzidan, Manpreet Kaur, El Mokhtar Essassi, Jerry P. Jasinski   +5 more
doaj   +1 more source

A New, Chiral Bis-Benzothiazine Ligand

, 2016
The synthesis and application of a new, chiral bis-benzothiazine ligand are ...
Michael Harmata (746967), Sunil K. Ghosh (2202520)   +1 more
core   +1 more source

A REVIEW: SYNTHESIS AND MEDICINAL IMPORTANCE OF 1,4-BENZOTHIAZINE ANALOGUES [PDF]

, 2015
The ultimate beneficiary of scientific advances is discovering new and better therapeutic agents. 1,4-benzothiazine forms an important class ofheterocyclic system, contains both N and S. Consequently, there have been various efforts for the production of
Maheshwari, Monika, Goyal, Anju
core   +1 more source