Results 31 to 40 of about 6,902 (250)

Positive allosteric modulators of the a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor [PDF]

, 2010
L-glutamate is the major excitatory neurotransmitter in the mammalian central nervous system (CNS) and plays a fundamental role in the control of motor function, cognition and mood.
Grove, Simon J .A., Jamieson, Craig, Maclean, John K. F., Morrow, John A., Rankovic, Zoran   +4 more
core   +1 more source

Bird Integumentary Melanins: Biosynthesis, Forms, Function and Evolution [PDF]

, 2016
Melanins are the ubiquitous pigments distributed in nature. They are one of the main pigments responsible for colors in living cells. Birds are among the most diverse animals regarding melanin-based coloration, especially in the plumage, although they ...
Agrup, Aroca, Bonser, Bortolotti, Brumbaugh, Carr, Chiaverini, Chintala, Colleary, Cott, Darwin, Domyan, D’Ischia, Francisco Solano, García-Borrón, Grande, Ismael Galván, Ito, Jimbow, Jiménez-Cervantes, Kerje, Lin, Liu, Mason, McGraw, McGraw, McGraw, Napolitano, Prota, Prum, Raper, Rorsman, Sato, Searcy, Solano, Straniero, Sultana, Tarafder, Van Grouw, Vinther, Wogelius   +40 more
core   +2 more sources

Crystal structure, Hirshfeld surface analysis and interaction energy and DFT studies of 1-(1,3-benzothiazol-2-yl)-3-(2-hydroxyethyl)imidazolidin-2-one

Acta Crystallographica Section E: Crystallographic Communications, 2020
In the title molecule, C12H13N3O2S, the benzothiazine moiety is slightly non-planar, with the imidazolidine portion twisted only a few degrees out of the mean plane of the former.
Mohamed Srhir, Nada Kheira Sebbar, Tuncer Hökelek, Ahmed Moussaif, Joel T. Mague, Noureddine Hamou Ahabchane, El Mokhtar Essassi   +6 more
doaj   +1 more source

rac-2,3-Diphenyl-2,3-dihydro-4H-pyrido[3,2-e][1,3]thiazin-4-one 1-oxide

IUCrData, 2017
In the title compound, C19H14N2O2S, the thiazine ring exhibits a screw-boat pucker. The oxygen atom on the sulfur atom of the ring is pseudo-axial on the thiazine ring.
Hemant P. Yennawar, Duncan J. Noble, Ziwei Yang, Lee J. Silverberg   +3 more
doaj   +1 more source

Signaling in a polluted world: oxidative stress as an overlooked mechanism linking contaminants to animal communication [PDF]

, 2016
The capacity to communicate effectively with other individuals plays a critical role in the daily life of an individual and can have important fitness consequences.
Costantini, David, Marasco, Valeria
core   +1 more source

Synthesis of quinazolino‐1,3‐benzothiazine derivatives

Journal of Heterocyclic Chemistry, 1992
AbstractThe ring‐closure reactions of N‐(3,4‐dimethoxyphenylthiomethyl)‐2‐nitrobenzamide derivatives 5a,b with phosphoryl chloride gave 4‐(2‐nitrophenyl)‐2H1,3‐benzothiazine derivatives 7a,b, which on reduction yielded 4‐(2′‐aminophenyl)‐3,4‐dihydro‐2H‐1,3‐benzothiazines 8a,b.
Szabó János, Bani-Akoto Ernest, Dombi György, Bernáth Gábor, Fodor Lajos, Sohár Pál   +5 more
openaire   +2 more sources

Crystallization and disorder of the polytypic α1 and α2 polymorphs of piroxicam [PDF]

, 2015
The polytypic α1and α2polymorphs of piroxicam are described and it is shown that they can be crystallized controllably.This work was funded by the Danish Council for Independent Research | Natural Sciences (DFF-1323-00122).This is the accepted manuscript.
Bond, AD, Upadhyay, PP
core   +2 more sources

Evaluation of 1,2-Benzothiazine 1,1-Dioxide Derivatives In Vitro Activity towards Clinical-Relevant Microorganisms and Fibroblasts

Molecules, 2020
The global concern related with growing number of bacterial pathogens, resistant to numerous antibiotics, prone scientific environment to search for new antimicrobials.
R. Dudek-Wicher, Berenika M. Szczęśniak-Sięga, R. Wiglusz, J. Janczak, M. Bartoszewicz, A. Junka   +5 more
semanticscholar   +1 more source

Truncated glucagon-like peptide-1 and exendin-4 α-conotoxin pl14a peptide chimeras maintain potency and α-helicity and reveal interactions vital for cAMP signaling in vitro [PDF]

, 2016
Glucagon-like peptide-1 (GE P-1) signaling through the glucagon-like peptide 1 receptor (GLP-1R) is a key regulator of normal glucose metabolism, and exogenous GLP-1R agonist therapy is a promising avenue for the treatment of type 2 diabetes mellitus. To
Craik, David J., Derksen, David R., Edmonds, David J., Fairlie, David P., Griffith, David A., Liras, Spiros, Loria, Paula M., Mitchell, Justin M., Price, David A., Ruggeri, Roger B., Schroeder, Christina I., Swedberg, Joakim E.   +11 more
core   +1 more source

Synthesis and Antimicrobial Activity of Some New 1, 4-Benzothiazine Containing Thiosemicarbazides and 1, 3, 4-Oxadiazole Derivatives

E-Journal of Chemistry, 2012
A series of novel 3- methyl-7-substituted-4H,4-benzothiazine-2-carbohydrazide (3a-e) and corresponding thiosemicarbazides (4-a-q); 2-[3-methyl-7-substituted- 4H -1, 4-benzothiazine-2-yl]-N-(aryl) hydrazine carbothiamide have been synthesized.
Bhikan J Khairnar, Rahul S. Salunke, Premchand B. Patil, Sanjay A . Patil, Rajeshwar J . Kapade, Pravin S. Girase, Bhata R. Chaudhari   +6 more
doaj   +1 more source