Results 11 to 20 of about 6,067 (184)
RNA-ligand docking is a part of computational biology, which is currently lowly recognized compared to the protein-ligand docking procedure commonly applied for drug discovery.
Adhityo Wicaksono +1 more
doaj +1 more source
Alkaloid Biosynthesis in the Early Stages of the Germination of Argemone mexicana L. (Papaveraceae)
The synthesis of the benzylisoquinoline alkaloids, sanguinarine and berberine, was monitored in Argemone mexicana L. (Papaveracea) throughout the early stages of its hypocotyl and seedling development.
Jorge Xool-Tamayo +4 more
doaj +1 more source
Toxicological Effects of Berberine and Sanguinarine
Berberine and Sanguinarine alkaloids belong to a group of naturally occurring chemical compounds that mostly contain basic nitrogen atoms. This group also includes some related compounds with neutral or weakly acidic properties. Alkaloids are produced by
Nitika Singh, Bechan Sharma
doaj +1 more source
Biological Activity of Berberine—A Summary Update
Berberine is a plant metabolite belonging to the group of isoquinoline alkaloids with strong biological and pharmacological activity. Currently, berberine is receiving considerable interest due to its anticancer activity based on many biochemical ...
Anna Och +2 more
doaj +1 more source
Natural bioactive compounds in Alzheimer's disease: From the perspective of type 3 diabetes mellitus
There is a close relationship between Alzheimer's disease (AD) and diabetes mellitus (DM), and the link between the two is often referred to as type 3 diabetes mellitus (T3DM).
Juan Huang +6 more
doaj +1 more source
Anticancer Potential of Natural Isoquinoline Alkaloid Berberine
Despite the availability of several therapeutic strategies and many drugs, the ability to cure most cancers remains a challenge. Natural products have been used for the treatment of numerous diseases, including cancer. The present review delineates various preclinical studies performed in vitro and in vivo that explore the anticancer potential of ...
openaire +1 more source
Background Up-and-down procedure (UDP) was recommended to replace traditional acute toxicity methods. However, it was limited due to the long experimental period (20–42 days).
Yan-Yu Zhang +3 more
doaj +1 more source
Berberine, an Epiphany Against Cancer
Alkaloids are used in traditional medicine for the treatment of many diseases. These compounds are synthesized in plants as secondary metabolites and have multiple effects on cellular metabolism.
Luis Miguel Guamán Ortiz +3 more
doaj +1 more source
Due to certain differences in terms of molecular structure, isoquinoline alkaloids from Chelidonium majus engage in various biological activities.
Sylwia Zielińska +7 more
doaj +1 more source
Goldenseal (Hydrastis canadensis L.) is a medicinal forest herb native to Appalachia. Its roots and rhizomes are used as an antimicrobial and for the treatment of intestinal ailments.
Grady H. Zuiderveen +2 more
doaj +1 more source

