Results 21 to 30 of about 6,067 (184)

Polymorphic Nucleic Acid Binding of Bioactive Isoquinoline Alkaloids and Their Role in Cancer

Journal of Nucleic Acids, 2010
Bioactive alkaloids occupy an important position in applied chemistry and play an indispensable role in medicinal chemistry. Amongst them, isoquinoline alkaloids like berberine, palmatine and coralyne of protoberberine group, sanguinarine of the ...
Motilal Maiti, Gopinatha Suresh Kumar
doaj   +1 more source

Chemical composition and anti-inflammatory effect of Phellodendron amurense Rupr. stem bark extract

Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 2023
In many diseases inflammation and oxidative stress coexist and are therapeutic targets. Phellodendron amurense Rupr. has anti-inflammatory and antioxidant effects, but the mechanisms are not completely elucidated. Therefore, first P.
Sabina-Emanuela ERHAN, Alina E. PÂRVU, Alexandra CIORÎȚĂ, Ayu A. PUTRI, Alexis J. VILLAGRANA MOLINA, Marcel PÂRVU, Augustin C. MOȚ   +6 more
doaj   +1 more source

Nanotechnology-Based Strategies for Berberine Delivery System in Cancer Treatment: Pulling Strings to Keep Berberine in Power

Frontiers in Molecular Biosciences, 2021
Cancer is a multifactorial disease characterized by complex molecular landscape and altered cell pathways that results in an abnormal cell growth.
Muhammad Javed Iqbal, Cristina Quispe, Zeeshan Javed, Haleema Sadia, Qamar Raza Qadri, Shahid Raza, Bahare Salehi, Natália Cruz-Martins, Natália Cruz-Martins, Natália Cruz-Martins, Zeinab Abdulwanis Mohamed, Mohammed Sani Jaafaru, Mohammed Sani Jaafaru, Ahmad Faizal Abdull Razis, Ahmad Faizal Abdull Razis, Ahmad Faizal Abdull Razis, Javad Sharifi-Rad, Javad Sharifi-Rad   +17 more
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Berberine enhances the anti-hepatocellular carcinoma effect of NK92-MI cells through inhibiting IFN-gamma-mediated PD-L1 expression

Liver Research, 2022
Background and aims: Berberine is one of the most promising clinically tested natural alkaloids, and immunotherapy using natural killer (NK) cells is a potentially effective treatment for hepatocellular carcinoma (HCC).
Kunyuan Wang, Chengxin Gu, Ganxiang Yu, Jiaen Lin, Zhilei Wang, Qianting Lu, Yangzhi Xu, Dan Zhao, Xiaofeng Jiang, Weijian Mai, Shiming Liu, Hui Yang   +11 more
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Anti-Acetylcholinesterase Activities of Mono-Herbal Extracts and Exhibited Synergistic Effects of the Phytoconstituents: A Biochemical and Computational Study

Molecules, 2019
Alzheimer’s disease (AD), a neurodegenerative disease, is the most common form of dementia. Inhibition of acetylcholinesterase (AChE) is a common strategy for the treatment of AD. In this study, aqueous, hydro-methanolic, and methanolic extracts of
Acharya Balkrishna, Subarna Pokhrel, Meenu Tomer, Sudeep Verma, Ajay Kumar, Pradeep Nain, Abhishek Gupta, Anurag Varshney   +7 more
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PREPARATIVE SEPARATION OF ISOQUINOLINE ALKALOIDS FROM PHELLODENDRI CORTEX BY PH-ZONE-REFINING COUNTER-CURRENT CHROMATOGRAPHY

Química Nova
pH-Zone-refining counter-current chromatography (PZRCCC) was successfully used for preparative separation isoquinoline alkaloids from Phellodendri Cortex.
Daijie Wang, Shanming Tian, Li Cui, Huijiao Yan, Xiangyun Song, Yuguo Liu, Fei Xu, Junjian Ma   +7 more
doaj   +1 more source

Interaction of Herbal Compounds with Biological Targets: A Case Study with Berberine

The Scientific World Journal, 2012
Berberine is one of the main alkaloids found in the Chinese herb Huang lian (Rhizoma Coptidis), which has been reported to have multiple pharmacological activities.
Xiao-Wu Chen, Yuan Ming Di, Jian Zhang, Zhi-Wei Zhou, Chun Guang Li, Shu-Feng Zhou   +5 more
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Protection and Delivery of Phytochemicals from Passive Encapsulation to Guaranteed Self‐Assembly Induced by Amyloid Template for Chronic Disease Prevention via Modulating Microbial‐Host Crosstalk

Advanced Science, EarlyView.
ABSTRACT The rising incidence of chronic diseases globally has drawn widespread attention to phytochemicals, which exert targeted preventive and alleviating effect by modulating gut microbiota; thus, a potential strategy for precision nutritional interventions is offered.
Shiqi Bai, Siying Cheng, Fengguang Ma, Xiaorong Zhang, Jianan Huang, Zhonghua Liu, Bing Hu   +6 more
wiley   +1 more source

A Review on Anticancer Potential of Berberis aristata and Berberine with Focus on Quantitative Methods

Journal of Preventive, Diagnostic and Treatment Strategies in Medicine, 2022
Berberis aristata (BA) is a traditional herbal ayurvedic medicine widely used from ancient time and has various therapeutic effect. In this review, we had tried to emphasize on its pharmacognistic as well phytochemical parameters.
Manasi Rokade, Vijaya Vichare, Tejaswini Neve, Bhagyashri Parande, Shashikant Dhole   +4 more
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Label‐Free and Immobilization‐Free Protein‐Binding Assays by Ultraviolet Transient Absorption Microscopy

Advanced Science, EarlyView.
A femtosecond UV pump–probe microscope resolves binding‐induced changes in protein excited‐state dynamics and converts these intrinsic contrasts into an equilibrium affinity readout. By probing tryptophan responses directly in solution, the approach enables quantitative determination of dissociation constants without labeling or immobilization ...
Jianghao Shen, Qiangqiang Wang, Fan Wu, Yang Gao, Lu Lan, Pu Wang   +5 more
wiley   +1 more source