Results 71 to 80 of about 104,722 (190)
Konfitüren, Säfte und Trocknung biologisch angebauter Lebensmittel: Was geschieht mit Allergenen während der Verarbeitung? [PDF]
, 2017 Food allergy is an increasing health problem, whereby plant allergens are one of the major source eliciting allergenic reactions. Ninety percent of birch pollen allergic patients develop intolerances to fruits and vegetables. Antibodies against Bet v 1,
Kurze, E., Schwab, Wilfried
core
BRD4 associates with p53 in DNMT3A-mutated leukemia cells and is implicated in apoptosis by the bromodomain inhibitor JQ1 [PDF]
, 2013 The bromodomain and extra terminal (BET) family protein bromodomain containing protein 4 (BRD4) is an epigenetic regulator recently identified as a therapeutic target for several hematological cancers, notably mixed lineage leukemia-fusion acute myeloid ...
Bastow, Sarah +3 more
core +1 more source
Cardiovascular Therapeutics, 2020 Chronic systemic inflammation contributes to cardiovascular disease (CVD) and correlates with the abundance of acute phase response (APR) proteins in the liver and plasma.
Sylwia Wasiak +12 more
doaj +1 more source
The emerging role of BET inhibitors in breast cancer
Breast, 2020 Bromodomain and extraterminal domain (BET) proteins are epigenetic molecules that regulate the expression of multiple genes involved in carcinogenesis.
Angeliki Andrikopoulou +4 more
doaj +1 more source
Structural basis of the allergenicity to strawberries due to Fra a 1.02 [PDF]
, 2018 Strawberry fruits are highly valued due to their flavor, aroma, and benefits for human health. Despite this, 30% of the population with food hypersensitivity also shows adverse reactions to strawberry (Franz-Oberdorf et al, 2016).
Casañal, Ana +8 more
core
Genomic characterization of putative allergen genes in peach/almond and their synteny with apple [PDF]
, 2008 Background - Fruits from several species of the Rosaceae family are reported to cause allergic reactions in certain populations. The allergens identified belong to mainly four protein families: pathogenesis related 10 proteins, thaumatin-like proteins ...
Chen, L. +9 more
core +3 more sources
BET Proteins are a Key Component of Immunoglobulin Gene Expression [PDF]
Epigenomics, 2017 BET proteins have been shown to regulate gene expression including inflammatory genes.In order to investigate the role of the BET proteins in immunoglobulin production we treated the human B-cell line CLNH11.4 and primary human B cells and ozone-exposed mice with BET inhibitors (JQ1 or IBET151).Both proliferation and IgG production were reduced by JQ1 ...
Shim, JM +7 more
openaire +4 more sources
Cell Reports, 2013 A hallmark of retroviral replication is integration of the viral genome into host cell DNA. This characteristic makes retrovirus-based vectors attractive delivery vehicles for gene therapy.
Jan De Rijck +11 more
doaj +1 more source
Bromodomain and Extra Terminal (BET) Inhibitor Suppresses Macrophage-Driven Steroid-Resistant Exacerbations of Airway Hyper-Responsiveness and Inflammation. [PDF]
PLoS ONE, 2016 Exacerbations of asthma are linked to significant decline in lung function and are often poorly controlled by corticosteroid treatment. Clinical investigations indicate that viral and bacterial infections play crucial roles in the onset of steroid ...
Thi Hiep Nguyen +4 more
doaj +1 more source
Frontiers in Oncology, 2022 BackgroundColorectal cancer (CRC) frequently has a dysregulated epigenome causing aberrant up-regulation of oncogenes such as c-MYC. Bromodomain and extra-terminal domain (BET) proteins and histone acetyltransferases (HAT) are epigenetic regulatory ...
Chaoyuan Kuang +18 more
doaj +1 more source