Results 1 to 10 of about 174,626 (254)

Beta-Alanine and Aquagenic Pruritus: Proposed Neuroimmune Mechanism. [PDF]

JMIR Dermatol
Aquagenic pruritus (AP) is a rare itch disorder with limited effective treatments, and emerging clinical observations suggest that oral β-alanine may reduce symptoms.
Piserchio N, Baratta B, Brooks B, Muse B, Ball K.   +4 more
europepmc   +2 more sources

Recent Advances in Beta-Alanine Production via Enzymatic Catalysis and Microbial Whole-Cell Catalysis [PDF]

Biology
Beta-alanine, a naturally occurring non-proteinogenic beta-amino acid, is widely used in delaying fatigue, enhancing exercise performance, and alleviating hyperuricemia.
Jie Yu, Peikun Ma, Jiabei Zhang, Hongyang Zhang, Hang Tie, Haihua Ruan   +5 more
doaj   +2 more sources

Comparative Analysis of Chemical Constituents in Peppers from Different Regions by Integrated LC-MS and GC-MS Non-Targeted Metabolomics [PDF]

Metabolites
Background/Objectives: The quality of dried chili peppers is critically influenced by geographical origin, yet the metabolic basis for these differences remains insufficiently explored.
Xuefeng Gong, Sihao Hou, Yi Xu, Hong Li, Xin Chen, Zhanfeng Song   +5 more
doaj   +2 more sources

Na+/Ca2+ exchanger isoform 1 takes part to the Ca2+-related prosurvival pathway of SOD1 in primary motor neurons exposed to beta-methylamino-l-alanine

Cell Communication and Signaling, 2022
Background The cycad neurotoxin beta-methylamino-l-alanine (L-BMAA), one of the environmental trigger factor for amyotrophic lateral sclerosis/Parkinson-dementia complex (ALS/PDC), may cause neurodegeneration by disrupting organellar Ca2+ homeostasis ...
Tiziana Petrozziello, Francesca Boscia, Valentina Tedeschi, Anna Pannaccione, Valeria de Rosa, Angela Corvino, Beatrice Severino, Lucio Annunziato, Agnese Secondo   +8 more
doaj   +2 more sources

The β-alanine transporter BalaT is required for visual neurotransmission in Drosophila

eLife, 2017
The recycling of neurotransmitters is essential for sustained synaptic transmission. In Drosophila, histamine recycling is required for visual synaptic transmission.
Yongchao Han, Liangyao Xiong, Ying Xu, Tian Tian, Tao Wang   +4 more
doaj   +2 more sources

Integrative Pathway Analysis of Genes and Metabolites Reveals Metabolism Abnormal Subpathway Regions and Modules in Esophageal Squamous Cell Carcinoma

Molecules, 2017
Aberrant metabolism is one of the main driving forces in the initiation and development of ESCC. Both genes and metabolites play important roles in metabolic pathways. Integrative pathway analysis of both genes and metabolites will thus help to interpret
Chunquan Li, Qiuyu Wang, Jiquan Ma, Shengshu Shi, Xin Chen, Haixiu Yang, Junwei Han   +6 more
doaj   +2 more sources

Integrated metabolomic profiling identifies citrate as novel diagnostic biomarker for Anti-MDA5-Positive dermatomyositis [PDF]

Arthritis Research & Therapy
Objective Anti-melanoma differentiation-associated gene 5-positive dermatomyositis (anti-MDA5 + DM) is a unique subtype of idiopathic inflammatory myopathy (IIM) with a poorer prognosis.
Tianqi Li, Jinlei Sun, Ting Li, Junyao Liu, Yi Cao, Peiling Liu, Cong Wang, Fang Dong, Liangzhi Liu, Wenhui Lou, Shengyun Liu, Yusheng Zhang, Panpan Zhang   +12 more
doaj   +2 more sources

GC-MS-based untargeted metabolic profiling of malignant mesothelioma plasma [PDF]

PeerJ, 2023
Background Malignant mesothelioma (MM) is a cancer caused mainly by asbestos exposure, and is aggressive and incurable. This study aimed to identify differential metabolites and metabolic pathways involved in the pathogenesis and diagnosis of malignant ...
Ding Wang, Jing Zhu, Na Li, Hongyang Lu, Yun Gao, Lei Zhuang, Zhongjian Chen, Weimin Mao   +7 more
doaj   +2 more sources

Comparative Transcriptomic Analysis Reveals Salt Stress Adaptation Mechanisms in Cultivated Rice Varieties (Oryza sativa)

Current Issues in Molecular Biology
Salt stress is an injurious concern of global climate change that negatively impacts the growth and yield of rice plants. Identifying salt tolerance genes is essential to understanding the molecular mechanism regulating salt tolerance in rice.
Zihao Yuan, Ziqi Liu, Shengyu Mo, Feng Wang, Wuge Liu, Dilin Liu, Wu Yang, Yilong Liao, Leiqing Chen, Le Kong, Hui Wang, Tao Guo, Xing Huo   +12 more
doaj   +2 more sources

Ogfod1 deletion increases cardiac beta-alanine levels and protects mice against ischemia-reperfusion injury.

Cardiovascular Research, 2021
AIMS Prolyl hydroxylation is a post-translational modification that regulates protein stability, turnover, and activity. The proteins that catalyze prolyl hydroxylation belong to the 2-oxoglutarate- and iron-dependent oxygenase family of proteins.
Michael Harris, Junhui Sun, Karen J Keeran, A. Aponte, Komudi Singh, D. Springer, M. Gucek, M. Pirooznia, M. Cockman, E. Murphy, Leslie M. Kennedy   +10 more
semanticscholar   +1 more source