Results 101 to 110 of about 63,634 (227)

Pharmacokinetic aspects of beta-lactam antibiotic therapy in intensive care unit patients: A one-center experience with TDM [PDF]

, 2020
Kateřina Sadilová, Milada Halačová, Dalibor Černý   +2 more
openalex   +1 more source

Time‐dependent wound management protocol prevents periprosthetic joint infection in total knee arthroplasty with persistent drainage

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This study aimed to evaluate the success rate of a standardised protocol for managing persistent wound drainage following total knee arthroplasty (TKA). Methods A prospective observational study was conducted at four institutions between January and June 2022 across primary and revision TKAs.
Filippo Leggieri, Francesco Ferriani, Enrico Di Benedetto, Enrick Miani, Enrico Festa, Giovanni Balato, Stefano M. P. Rossi, Francesco Benazzo, Andrea Baldini   +8 more
wiley   +1 more source

Modifying Antibiotic Activity of Synthetic Thiadiazine Analogs Against MDR Bacteria and ADMET Analysis

ChemistryOpen, EarlyView.
The study demonstrated that thidiazine compounds potentiated the action of antibiotics. The compounds associated with norfloxacin against S. aureus showed greater significance in relation to the other medications. The indiscriminate use of antibiotics has led to the selection of resistant bacterial strains, significantly reducing the effectiveness of ...
João Arthur de Oliveira Borges, Priscilla Ramos Freitas, Isaac Moura Araújo, Ray Silva de Almeida, Igor José dos Santos Nascimento, João Xavier de Araújo‐Júnior, Edeildo Ferreira da Silva‐Júnior, Thiago Mendonça de Aquino, Francisco Jaime Bezerra Mendonça Junior, Emmanuel Silva Marinho, Hélcio Silva dos Santos, Radosław Kowalski, Grażyna Kowalska, Henrique Douglas Melo Coutinho, Saulo Relison Tintino, Ana Carolina Justino de Araújo   +15 more
wiley   +1 more source

Green Synthesis of ZnO Nanoparticles From Spirulina platensis: Antimicrobial and Cytotoxic Evaluation With Molecular Docking Studies

ChemistryOpen, EarlyView.
Algal‐extract‐derived ZnO nanoparticles show shape anisotropy and are bio capped by phytochemicals. These green‐synthesized NPs strongly inhibit S. aureus and K. pneumoniae biofilms. Molecular docking suggests stable binding of surface biomolecules to microbial targets, highlighting synergistic antibacterial mechanisms.
Muhammad Rizwan, Izaz Khan, Syed Sikandar Shah, Amir hamza khan, Abdurahman Hajinur Hirad, Saira Naz, Arshad Farid, Taimoor Khan, Said Hassan   +8 more
wiley   +1 more source

Beta-lactam antibiotic administration in critically ill children with sepsis: an international survey of current practice [PDF]

Sainath Raman, Raju Reddy, Daniela Carla de Souza, Richard F. Cox, Renate Le Marsney, Karthi Nallasamy, Padmanabhan Ramnarayan, Jason A. Roberts, Luregn J. Schlapbach, Kristen Gibbons, Tatjana Kerig, Jennifer Darvas, Marino Festa, Shane George, Corrine R Balit, Felix Oberender, Simon Erickson, Jenipher Chumbes Flores, Karina Charles, Michaela Waak, Debbie Long, Warwick Butt, Carmel Delzoppo, Ben Gelbart, Kate Masterson, Johnny Millar, Anusha Ganeshalingam, Claire Sherring, Puneet Singh, Vicky Smith, Vicky Smith   +30 more
openalex   +1 more source

Evaluation of the Potential Carrier and Controlled Release of Antibiotics by Zinc, Nickel, and Cobalt Ferrite Nanoparticles Encapsulated with Silica and Functionalized with Moxifloxacin Hydrochloride

Particle &Particle Systems Characterization, EarlyView.
The study reveals the inhibitory potential of encapsulated nanoparticles functionalized with moxifloxacin hydrochloride. ABSTRACT Bacterial resistance represents a significant global health threat associated with the development of microbial resistance genes.
Amanda S. Abreu, Stéfanne R. R. Ferreira, Naiara G. Cabral, Romayne P. França, Hanstter H. A. Rezende, Richard Landers, Alexandre Pancotti   +6 more
wiley   +1 more source

A protocol for a multicentre randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients with severe sepsis: the BLING II study

, 2013
Joel M. Dulhunty, Jason A. Roberts, Joshua S. Davis, S. A. R. Webb, Rinaldo Bellomo, Charles D. Gomersall, Charudatt Shirwadkar, Glenn M. Eastwood, John Myburgh, David L. Paterson, Therese Starr, Andrew Udy, Sanjoy K. Paul, Jeffrey Lipman   +13 more
openalex   +1 more source

Beta-lactam allergy in patients: an antibiotic stewardship challenge

, 2022
Julia Bodega-Azuara, M. Dolores Bellés Medall, Josep Edo-Peñarrocha, Aarón Puplá-Bartoll, Raúl Ferrando Piqueres, MarÍa Cruz Torres-Górriz, Adrián Germán-Sánchez, Ernesto Enrique   +7 more
openalex   +2 more sources

Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases

Rare Metals, EarlyView.
ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan, Shengjie Xue, Junyi Yin, Shaolei Wang, Yunlei Zhou, Jieyue Liao   +5 more
wiley   +1 more source

Studies on .BETA.-lactam antibiotics. IV Structure-activity relationships of 7.BETA.-((z)-2-alkoxyimino-2-(2-amino-4-thiazolyl)acetamido)-3-cephem-4-carboxylic acids.

, 1981
TAKAO TAKAYA, Hisashi Takasugi, TAKASHI MASUGI, HIROMU KOCHI, Hiroshi Nakano   +4 more
openalex   +2 more sources