Results 41 to 50 of about 206,426 (300)

beta 2-Glycoprotein I and anti-beta 2-glycoprotein I antibodies: where are we now? [PDF]

Rheumatology, 1997
beta 2-Glycoprotein I (beta 2-GPI), a plasma protein with in vitro anticoagulant properties, has been recognized to have an important role in the antiphospholipid syndrome (APS) as a cofactor and an (co)antigen in ELISA assays. Although beta 2-GPI levels were found to be increased in some patients with APS, the clinical value of measuring beta 2-GPI ...
openaire   +1 more source

Anticardiolipin and anti-beta-2-glycoprotein I antibodies

Autoimmunity, 2005
The anticardiolipin (aCL) antibody test was first established in 1983, using cardiolipin (negatively charged phospholipid) as an antigen in a solid-phase immunoassAy. It was first applied to the study of systemic lupus erythematosus patients, and was found associated with thromboses and recurrent pregnancy losses.
Marai I, TINCANI, Angela, Balestrieri G, Shoenfeld Y.   +3 more
openaire   +3 more sources

Anticardiolipin and anti-beta 2 glycoprotein-I antibodies disappearance in patients with systemic lupus erythematosus and antiphospholipid syndrome while on belimumab

Annals of the Rheumatic Diseases, 2018
Savino Sciascia, Elena Rubini, Massimo Radin, Irene Cecchi, Daniela Rossi, Dario Roccatello   +5 more
openalex   +3 more sources

Antiphospholipid Antibodies and Antiphospholipid Syndrome During Pregnancy: Diagnostic Concepts

Frontiers in Immunology, 2015
Antiphospholipid syndrome comprises of a wide spectrum of clinical and obstetric manifestations linked to the presence of antiphospholipid antibodies. APS was described in the context of lupus and later as an isolated syndrome or primary APS.
Roger A Levy, Flavia eCunha, Guilherme R de Jesús, Nilson R de Jesús   +3 more
doaj   +1 more source

Structure-function relationships for the interleukin 2 receptor system

Memorias do Instituto Oswaldo Cruz, 1987
Receptors for interleukin 2 (IL-2) esit in at least three forms which differ in their subunit compositio, their affinity for ligand and their ability to mediate a cellular reponse.
Richard J. Robb
doaj   +1 more source

Studies on specific interaction of beta-2-glycoprotein I with HBsAg

World Journal of Gastroenterology, 2003
To observe the binding activity of beta-2-glycoprotein I(beta(2)GPI) to hepatitis B surface antigen (HBsAg) and the possible roles of beta(2)GPI in hepatitis B virus (HBV) infection.The rationale of ELISA methods and ELISA-based research method and ligand-blotting technique were used to detect the specific interaction of beta(2)GPI with HBsAg.With the ...
Pu-Jun, Gao, Yun-Feng, Piao, Xiao-Dong, Liu, Li-Ke, Qu, Yang, Shi, Xiao-Cong, Wang, Han-Yi, Yang   +6 more
openaire   +2 more sources

OsVTC1-1 RNAi Mutant with Reduction of Ascorbic Acid Synthesis Alters Cell Wall Sugar Composition and Cell Wall-Associated Proteins

Agronomy, 2022
Ascorbic acid (AsA) or Vitamin C is an antioxidant molecule and plays an important role in many biological processes in plants. GDP-D-mannose pyrophosphorylase (GMP or VTC1) catalyzes the synthesis of GDP-D-mannose, which is a precursor for AsA ...
Kanyanat Lamanchai, Deborah L. Salmon, Nicholas Smirnoff, Pornsawan Sutthinon, Sittiruk Roytrakul, Kantinan Leetanasaksakul, Suthathip Kittisenachai, Chatchawan Jantasuriyarat   +7 more
doaj   +1 more source

Differences in Endothelial Activation and Dysfunction Induced by Antiphospholipid Antibodies Among Groups of Patients With Thrombotic, Refractory, and Non-refractory Antiphospholipid Syndrome

Frontiers in Physiology, 2021
Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by pregnancy morbidity or thrombosis and persistent antiphospholipid antibodies (aPL) that bind to the endothelium and induce endothelial activation, which is evidenced by the ...
Manuela Velásquez, Luisa F. Peláez, Mauricio Rojas, Raúl Narváez-Sánchez, Jesús A. Velásquez, Carlos Escudero, Carlos Escudero, Carlos Escudero, Sebastián San Martín, Sebastián San Martín, Sebastián San Martín, Ángela P. Cadavid, Ángela P. Cadavid, Ángela P. Cadavid   +13 more
doaj   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Comparative Binding Ability of Human Monoclonal Antibodies against Omicron Variants of SARS-CoV-2: An In Silico Investigation

Antibodies, 2023
Mutation(s) in the spike protein is the major characteristic trait of newly emerged SARS-CoV-2 variants such as Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), Delta (B.1.617.2), and Delta-plus.
Nabarun Chandra Das, Pritha Chakraborty, Jagadeesh Bayry, Suprabhat Mukherjee   +3 more
doaj   +1 more source