Results 1 to 10 of about 163,717 (335)

NKX2-5 regulates the expression of beta-catenin and GATA4 in ventricular myocytes. [PDF]

PLoS ONE, 2009
The molecular pathway that controls cardiogenesis is temporally and spatially regulated by master transcriptional regulators such as NKX2-5, Isl1, MEF2C, GATA4, and beta-catenin.
Ali M Riazi, Jun K Takeuchi, Lisa K Hornberger, Syed Hassan Zaidi, Fariba Amini, John Coles, Benoit G Bruneau, Glen S Van Arsdell   +7 more
doaj   +15 more sources

A reappraisal of transcriptional regulation by NR5A1 and beta-catenin in adrenocortical carcinoma [PDF]

Frontiers in Endocrinology, 2023
BackgroundOverexpression of the transcription factor NR5A1 and constitutive activation of canonical Wnt signalling leading to nuclear translocation of beta-catenin are hallmarks of malignancy in adrenocortical carcinoma (ACC).
Enzo Lalli, Enzo Lalli, Enzo Lalli
doaj   +2 more sources

Dlg1 activates beta-catenin signaling to regulate retinal angiogenesis and the blood-retina and blood-brain barriers

eLife, 2019
Beta-catenin (i.e., canonical Wnt) signaling controls CNS angiogenesis and the blood-brain and blood-retina barriers. To explore the role of the Discs large/membrane-associated guanylate kinase (Dlg/MAGUK) family of scaffolding proteins in beta-catenin ...
Chris Cho, Yanshu Wang, Philip M Smallwood, John Williams, Jeremy Nathans   +4 more
doaj   +2 more sources

Transcriptome analysis of beta-catenin-related genes in CD34+ haematopoietic stem and progenitor cells from patients with AML [PDF]

Mediterranean Journal of Hematology and Infectious Diseases
Background: Acute myeloid leukaemia(AML) is a disease of the haematopoietic stem cells. Beta-catenin, a key element of the Wnt signalling, which is particularly active in various cancers.
Buket Altinok Gunes, Tulin OZKAN, Aynur Karadag Gurel, Semih Dalkilic, Nevin Belder, Zeynep Ozkeserli, Hilal Ozdag Sevgili, Meral Beksac, Nilgun Sayinalp, Abdullah Munci Yagci, Asuman Sunguroglu   +10 more
doaj   +2 more sources

THOC1 binds to U2AF2 and regulates ovarian cancer progression through the beta-catenin / c-myc / cyclinD1 signaling pathway. [PDF]

Cancer Cell Int
Feng Y, Liu J, Zhang S, Zhang Z, Zhang D, Cao Y, Li M.   +6 more
europepmc   +2 more sources

Evaluation of Immunohistochemical Expression of Beta-catenin and E-cadherin as Epithelial-Mesenchymal Transition Markers in Colorectal Carcinoma - An Analytical Retrospective Study in a Tertiary Care Center. [PDF]

Int J Appl Basic Med Res
Katta R, Nugala S, Kolakonda M, Chinnam A.   +3 more
europepmc   +2 more sources

Immunohistochemical expression of beta-catenin in ampullary adenocarcinoma: a cross-sectional retrospective study. [PDF]

Ann Med Surg (Lond), 2023
Mirza SA, Hilmi MN, Al Jaleeli AN.
europepmc   +2 more sources

CP-09. HTDS ON NOVEL CELL LINES IDENTIFIED BETA-CATENIN INHIBITOR TEGATRABETAN AND PROTEASOME INHIBITOR BORTEZOMIB AS TWO NOVEL POTENTIAL AGENTS AGAINST ADAMANTINOMATOUS CRANIOPHARYNGIOMA [PDF]

Neuro Oncol
Carolina Cocito, Christopher C Padilla, David J. Pisapia, Charli Ann J. Hertz, Nadia Dahmane, Jeffrey P. Greenfield   +5 more
europepmc   +3 more sources

β-Catenin signaling increases during melanoma progression and promotes tumor cell survival and chemoresistance. [PDF]

PLoS ONE, 2011
Beta-catenin plays an important role in embryogenesis and carcinogenesis by controlling either cadherin-mediated cell adhesion or transcriptional activation of target gene expression.
Tobias Sinnberg, Moritz Menzel, Daniel Ewerth, Birgit Sauer, Michael Schwarz, Martin Schaller, Claus Garbe, Birgit Schittek   +7 more
doaj   +1 more source

GSK3beta is involved in JNK2-mediated beta-catenin inhibition. [PDF]

PLoS ONE, 2009
We have recently reported that mitogen-activated protein kinase (MAPK) JNK1 downregulates beta-catenin signaling and plays a critical role in regulating intestinal homeostasis and in suppressing tumor formation.
Dong Hu, Xiuli Bi, Wenfeng Fang, Anjia Han, Wancai Yang   +4 more
doaj   +1 more source