Results 51 to 60 of about 22,851 (287)

Structure and Characterization of KSc(BH4)(4) [PDF]

, 2010
A new potassium scandium borohydride, KSc(BH4)(4), is presented and characterized by a combination of in situ synchrotron radiation powder X-ray diffraction, thermal analysis, and vibrational and NMR spectroscopy.
Severa, Godwin, Ravnsbæk, Dorthe B., Yaroslav Filinchuk, Jensen, Torben R., Torben R. Jensen, Hagemann, Hans, Haase, Dörthe, Hagemann, Hans-Rudolf, Haase, Dörthe,, Cerny, Radovan, Vincenza D’ Anna, Jensen, Craig M., Jørgen Skibsted, Ravnsbaek, Dorthe B., Radovan C ˇ Erný, Hans Hagemann, D' Anna, Vincenza, Skibsted, Jorgen, Dorthe B. Ravnsbæk, Godwin Severa, Skibsted, Jørgen, D'Anna, Vincenza, Dörthe Haase, Filinchuk, Yaroslav, Craig M. Jensen, Radovan Černý, Vincenza D Anna, Lund University., D’ Anna, Vincenza   +28 more
core   +1 more source

Characterization of the Protective Effect of Tetrahydrobiopterin Against S-Nitroso-N -Acetyl-D ,L-Penicillamine Induced Endothelial Cell Injury

Pteridines, 1999
The purpose of this study was to characterize the protective effect of tetrahydrobiopterin (BH4), one of the cofactors of nitric oxide (NO) synthase, against NO-induced endothelial cell injury. The addition of S-nitroso-N-acetyl-D,L-penicillamine (SNAP),
Ishii Masakazu, Shimizu Shunichi, Momose Kazutaka, Kiuchi Yuji, Yamamoto Toshinori   +4 more
doaj   +1 more source

Endogenous tetrahydrobiopterin in humans: circadian rhythm, sex, race, age, and disease status

Frontiers in Pharmacology
Introduction6R-L-erythro-5,6,7,8-tetrahydrobiopterin (BH4) is an essential cofactor for multiple enzymes, including phenylalanine hydroxylase (PAH). Exogenous BH4, or its natural precursor sepiapterin, is utilized to treat patients with phenylketonuria ...
Lan Gao, Neil Smith, Ronald Kong
doaj   +1 more source

Intestinal Uptake of 6(R)-L-erythro-Tetrahydrobiopterin is Distinct from the Liver-Type MTX-Sensitive Accumulation Process

Pteridines, 2005
In order to increase the tissue level of tetrahydrobiopterin (BH4 ) , supplementation with 6R-tetrahydrobiopterin (6RBH4) has been widely employed. In this work, the profile of BH4 accumulation was compared between the liver and the small intestine after
Sawabe Keiko, Suetake Yasuko, Wakasugi Kazunori Osuke, Hasegawa Hiroyuki   +3 more
doaj   +1 more source

Tetrahydrobiopterin Protects against Radiation-induced Growth Inhibition in H9c2 Cardiomyocytes

Chinese Medical Journal, 2016
Background: Tetrahydrobiopterin (BH4) is an essential cofactor of nitric oxide synthases (NOSs) for the synthesis of nitric oxide (NO). BH4 therapy can reverse the disease-related redox disequilibrium observed with BH4 deficiency.
Zheng-Yi Zhang, Yi Li, Rui Li, An-An Zhang, Bo Shang, Jing Yu, Xiao-Dong Xie   +6 more
doaj   +1 more source

Physics‐Grounded Materials Artificial Intelligence for Reliable Materials Discovery

Advanced Functional Materials, EarlyView.
Physics‐Grounded Materials AI (PhysMat AI) integrates physical priors, descriptors, constraints, verification, and data infrastructure into a unified full‐stack framework, enabling reliable, interpretable, and autonomous AI‐driven materials discovery.
Yuhang Wang, Qian Wang, Seong‐Hoon Jang, Hao Li   +3 more
wiley   +1 more source

Reversible Calcium Alloying on Bulk and Indium (Sub)‐Micro Negative Electrodes for Calcium‐Based Batteries

Advanced Functional Materials, EarlyView.
Description: Indium metal serves as a reversible calcium‐alloying negative electrode. By transitioning from planar electrodes to powders and (sub‐)micron indium particles, the specific surface area is increased, improving the areal capacity density and cycling stability for calcium‐based batteries.
Wouter Monnens, Robert Markowski, Zhenyu Zhou, Claude Poleunis, Livia Grgurić, Jan Bitenc, Pingping Tan, Han‐Hung Hsu, Alexandru Vlad, Koen Binnemans, Jan Fransaer   +10 more
wiley   +1 more source

Insulin Stimulates Tetrahydrobiopterin Synthesis in Mouse Brain Microvascular Endothelial Cells

Pteridines, 1999
We examined the effects of insulin on tetrahydrobiopterin (BH4) synthesis in mouse brain microvascular endothelial cells (MBMECs). Treatment of MBMECs with insulin increased the intracellular BH4 content in a time- and concentration-dependent manner. The
Ishi Masakazu, Shimizu Shunichi, Nagai Tsutomu, Kiuchi Yuji, Yamamoto Toshinori   +4 more
doaj   +1 more source

Tetrahydrobiopterin Uptake in Supplemental Administration: Elevation of Tissue Tetrahydrobiopterin in Mice Following Uptake of the Exogenously Oxidized Product 7,8-Dihydrobiopterin and Subsequent Reduction by an Anti-folate-Sensitive Process

Journal of Pharmacological Sciences, 2004
In order to increase the tissue level of tetrahydrobiopterin (BH4), supplementation with 6R-tetrahydrobiopterin (6RBH4) has been widely employed. In this work, the effectiveness of 6RBH4 was compared with 7,8-dihydrobiopterin (7,8BH2) and sepiapterin by ...
Keiko Sawabe, Kazunori Osuke Wakasugi, Hiroyuki Hasegawa   +2 more
doaj   +1 more source

A fat-derived metabolite regulates a peptidergic feeding circuit in Drosophila. [PDF]

PLoS Biology, 2017
Here, we show that the enzymatic cofactor tetrahydrobiopterin (BH4) inhibits feeding in Drosophila. BH4 biosynthesis requires the sequential action of the conserved enzymes Punch, Purple, and Sepiapterin Reductase (Sptr).
Do-Hyoung Kim, Minjung Shin, Sung-Hwan Jung, Young-Joon Kim, Walton D Jones   +4 more
doaj   +1 more source