Results 31 to 40 of about 22,851 (287)

The metabolite BH4 controls T–cell proliferation in autoimmunity and cancer

Nature, 2018
Genetic regulators and environmental stimuli modulate T cell activation in autoimmunity and cancer. The enzyme co-factor tetrahydrobiopterin (BH4) is involved in the production of monoamine neurotransmitters, the generation of nitric oxide, and pain1,2 ...
Shane J.F. Cronin, C. Seehus, A. Weidinger, S. Talbot, S. Reissig, M. Seifert, Y. Pierson, E. McNeill, M. Longhi, B. Turnes, Taras Kreslavsky, Melanie Kogler, David Hoffmann, Melita Ticevic, D. da Luz Scheffer, L. Tortola, Domagoj Cikes, A. Jais, M. Rangachari, Shuan Rao, M. Paolino, M. Novatchkova, M. Aichinger, Lee B. Barrett, Alban Latremoliere, Gerald Wirnsberger, Guenther Lametschwandtner, M. Busslinger, Stephen Zicha, A. Latini, S. Robson, A. Waisman, N. Andrews, M. Costigan, K. Channon, G. Weiss, A. Kozlov, M. Tebbe, K. Johnsson, C. Woolf, J. Penninger   +40 more
semanticscholar   +1 more source

Halide substitution in Ca(BH4)(2) [PDF]

, 2014
Halide substitution in Ca(BH4)2 has been investigated in ball milled mixtures of Ca(BH4)2 and CaX2 (X 1⁄4 F, Cl, Br) with different molar ratios. In situ synchrotron radiation powder X-ray diffraction measurements of Ca(BH4)2 + CaCl2 with 1 : 0.5, 1 : 1 ...
Ugliengo, Piero, Marcello Baricco, Jensen, Torben R., Torben R. Jensen, Bjørn C. Hauback, Baricco, Marcello, Magnus H. Sørby, Hilde Grove, Grove, Hilde, Corno, Marta, Sørby, Magnus Helgerud, Line H. Rude, Rude, Line H., Hauback, Bjørn, Piero Ugliengo   +14 more
core   +1 more source

Treatment With Tetrahydrobiopterin Improves White Matter Maturation in a Mouse Model for Prenatal Hypoxia in Congenital Heart Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Reduced oxygen delivery in congenital heart disease causes delayed brain maturation and white matter abnormalities in utero. No treatment currently exists. Tetrahydrobiopterin (BH4) is a cofactor for neuronal nitric oxide synthase.
Jennifer Romanowicz, Camille Leonetti, Zaenab Dhari, Ludmila Korotcova, Shruti D. Ramachandra, Nemanja Saric, Paul D. Morton, Shivani Bansal, Amrita Cheema, Vittorio Gallo, Richard A. Jonas, Nobuyuki Ishibashi   +11 more
doaj   +1 more source

Improved hydrogen storage performances of LiAlH4 + Mg(BH4)2 composite with TiF3 addition

International Journal of Energy Research, 2020
This paper studies on the preparation of the alanate‐borohydride combined system, LiAlH4 + Mg(BH4)2 with diverse molar ratios (1:1, 1:2, and 2:1) using the ball milling technique.
N. N. Sulaiman, M. Ismail, S. N. Timmiati, K. Lim   +3 more
semanticscholar   +1 more source

Mg3(BH4)4(NH2)2 as Inorganic Solid Electrolyte with High Mg2+ Ionic Conductivity

ACS Applied Energy Materials, 2020
Mg3(BH4)4(NH2)2 compound was synthesized through the investigation of the Mg(BH4)2-Mg(NH2)2 phase diagram; its crystal structure was solved in a tetragonal unit cell with the space group I4.
Ronan Le Ruyet, B. Fleutot, R. Berthelot, Yasmine Benabed, G. Hautier, Y. Filinchuk, R. Janot   +6 more
semanticscholar   +1 more source

Theoretical and experimental study on Mg(BH4)2–Zn(BH4)2 mixed borohydrides [PDF]

Journal of Alloys and Compounds, 2013
Abstract After a screening of possible systems prone to give an enthalpy of decomposition close to 30 kJ mol H 2 - 1 , i.e. suitable for a dehydrogenation process close to room temperature and pressure, the Zn dissolution into Mg(BH4)2 has been investigated.
ALBANESE, ELISA, G. Kalantzopoulos, VITILLO, Jenny Grazia, PINATEL, EUGENIO RICCARDO, CIVALLERI, Bartolomeo, S. Deledda, BORDIGA, Silvia, B. Hauback, BARICCO, Marcello   +8 more
openaire   +4 more sources

Tetrahydrobiopterin: Beyond Its Traditional Role as a Cofactor

Antioxidants, 2023
Tetrahydrobiopterin (BH4) is an endogenous cofactor for some enzymatic conversions of essential biomolecules, including nitric oxide, and monoamine neurotransmitters, and for the metabolism of phenylalanine and lipid esters.
Tuany Eichwald, Lucila de Bortoli da Silva, Ananda Christina Staats Pires, Laís Niero, Erick Schnorrenberger, Clovis Colpani Filho, Gisele Espíndola, Wei-Lin Huang, Gilles J. Guillemin, José E. Abdenur, Alexandra Latini   +10 more
doaj   +1 more source

Structural diversity in the borohydrido lanthanides series: first isolation and X Ray crystal structure of ionic [Sm(BH4)2(THF)5]+[Cp*'Sm(BH4)3]- [PDF]

, 2007
International audienceTwo new borohydrido complexes of samarium were prepared: [Sm(BH4)2(THF)5]+[Cp*'Sm(BH4)3]- (1) and Cp*'2Sm(BH4)(THF) (3) (Cp*' = C5Me4nPr).
Bonnet, Fanny, Baudry-Barbier, D., Barbier-Baudry, Denise, Vigier, Estelle, Hafid, A., Vigier, E., Hafid, Abderrafia, Visseaux, M., Visseaux, Marc, Kubicki, M. M., Kubicki, Marek M, Bonnet, Fabrice   +11 more
core   +1 more source

Hydrogen Peroxide Stimulates the LPS-induced Tetrahydrobiopterin Synthesis in Mouse Brain Microvascular Endothelial Cells

Pteridines, 2002
Tetrahydrobiopterin (BH4) is one of the cofactors for nitric oxide synthase (NOS), and also has a protective effect against reactive oxygen species (ROS)- and/or nitric oxide (NO)-induced cytotoxicities. Lipopolysaccharide (LPS) induces NO production and
Shiota Kazuhiro, Shimizu Shumchi, Ishii Masakazu, Yamamoto Shinichiro, Iwasaki Michiko, Yamamoto Toshinori, Kiuchi Yuji   +6 more
doaj   +1 more source

Cardiomyocyte tetrahydrobiopterin synthesis regulates fatty acid metabolism and susceptibility to ischaemia–reperfusion injury

Experimental Physiology, 2023
Tetrahydrobiopterin (BH4) is an essential cofactor for nitric oxide (NO) synthases in which its production of NO is crucial for cardiac function.
Sandy M. Chu, Lisa C. Heather, Surawee Chuaiphichai, Thomas Nicol, Benjamin Wright, Matthieu Miossec, Jennifer K. Bendall, Gillian Douglas, Mark J. Crabtree, Keith M. Channon   +9 more
doaj   +1 more source