Results 21 to 30 of about 10,809 (188)

Insulin Secretion in Response to L-Arginine under Decreasing Tetrahydrobiopterin Content

Pteridines, 2008
Tetrahydrobiopterin (BH4) content in the pancreas from GK (Goto-Kakizaki) rats as a type II diabetic model was markedly decreased compared to Wistar rats as a healthy control. Moreover, insulin stimulated BH4 synthesis in a hamster pancreatic β-cell line,
Ishii Masakazu, Shimizu Shunichi, Watabe Tatsuya, Kiuchi Yuji   +3 more
doaj   +1 more source

Tetrahydrobioterin (BH4) Pathway: From Metabolism to Neuropsychiatry

Current Neuropharmacology, 2021
Tetrahydrobipterin (BH4) is a pivotal enzymatic cofactor required for the synthesis of serotonin, dopamine and nitric oxide. BH4 is essential for numerous physiological processes at periphery and central levels, such as vascularization, inflammation, glucose homeostasis, regulation of oxidative stress and neurotransmission.
Fanet, H., Capuron, Lucile, Castanon, Nathalie, Calon, F., Vancassel, Sylvie   +4 more
openaire   +5 more sources

Differential Inhibition of Constitutive and Inducible Nitric Oxide Synthase in Vascular Endothelial Cells by Analogues of Tetrahydrobiopterin

Pteridines, 2002
In the vasculature, a physiologic production of nitric oxide (NO) is maintained by endothelial nitric oxide synthase (eNOS). Induction of inducible nitric oxide synthase (ÍNOS) under inflammatory conditions (e.g. septic shock) resulting in high levels of
Mueller Nicolas J, Walter Roland Β, Linscheid Philippe, Schaffner Andreas, Schoedon Gabriele   +4 more
doaj   +1 more source

Intestinal Uptake of 6(R)-L-erythro-Tetrahydrobiopterin is Distinct from the Liver-Type MTX-Sensitive Accumulation Process

Pteridines, 2005
In order to increase the tissue level of tetrahydrobiopterin (BH4 ) , supplementation with 6R-tetrahydrobiopterin (6RBH4) has been widely employed. In this work, the profile of BH4 accumulation was compared between the liver and the small intestine after
Sawabe Keiko, Suetake Yasuko, Wakasugi Kazunori Osuke, Hasegawa Hiroyuki   +3 more
doaj   +1 more source

Characterization of the Protective Effect of Tetrahydrobiopterin Against S-Nitroso-N -Acetyl-D ,L-Penicillamine Induced Endothelial Cell Injury

Pteridines, 1999
The purpose of this study was to characterize the protective effect of tetrahydrobiopterin (BH4), one of the cofactors of nitric oxide (NO) synthase, against NO-induced endothelial cell injury. The addition of S-nitroso-N-acetyl-D,L-penicillamine (SNAP),
Ishii Masakazu, Shimizu Shunichi, Momose Kazutaka, Kiuchi Yuji, Yamamoto Toshinori   +4 more
doaj   +1 more source

Tetrahydrobiopterin Protects against Radiation-induced Growth Inhibition in H9c2 Cardiomyocytes

Chinese Medical Journal, 2016
Background: Tetrahydrobiopterin (BH4) is an essential cofactor of nitric oxide synthases (NOSs) for the synthesis of nitric oxide (NO). BH4 therapy can reverse the disease-related redox disequilibrium observed with BH4 deficiency.
Zheng-Yi Zhang, Yi Li, Rui Li, An-An Zhang, Bo Shang, Jing Yu, Xiao-Dong Xie   +6 more
doaj   +1 more source

CO2‐Assisted Hydrolysis of NaBH4: A Multi‐Function Platform for Enhanced Hydrogen Release, Regeneration of NaBH4, and CO2‐to‐CH4 Conversion

Advanced Science, EarlyView.
CO2 significantly accelerates hydrogen release from aqueous NaBH4 without metal catalysts, eliminating the need for downstream separation. Ball‐milling the hydrolytic products with Mg regenerates NaBH4 with yields exceeding 76% while simultaneously producing methane.
Rui Han, Stella Zhang, Yan Dai, Michael Scott, Brandon He, Sadegh Shabani, Oliver Hutt, Matthew David, Zhenguo Huang   +8 more
wiley   +1 more source

Increasing Hydrogen Density with the Cation-Anion Pair BH4−-NH4+ in Perovskite-Type NH4Ca(BH4)3

Energies, 2015
A novel metal borohydride ammonia-borane complex Ca(BH4)2·NH3BH3 is characterized as the decomposition product of the recently reported perovskite-type metal borohydride NH4Ca(BH4)3, suggesting that ammonium-based metal borohydrides release hydrogen gas ...
Pascal Schouwink, Fabrice Morelle, Yolanda Sadikin, Yaroslav Filinchuk, Radovan Černý   +4 more
doaj   +1 more source

Crystal structures and properties of solvent-free LiYb(BH4)4−xClx, Yb(BH4)3 and Yb(BH4)2−xClx

RSC Advances, 2013
Metal borohydrides offer high theoretical storage capacity for solid state hydrogen storage. This work is aimed at the mechanochemical synthesis of Yb(BH4)3 from LiBH4 and YbCl3. Different synthesis routes resulted in three new compounds, LiYb(BH4)4−xClx, α-Yb(BH4)3 and β-Yb(BH4)3.
Jørn Eirik Olsen, Christoph Frommen, Magnus H. Sørby, Bjørn C. Hauback   +3 more
openaire   +1 more source

Mixed‐Coordination Electrolytes With Molecular Additives for Robust Interphases in High‐Voltage Rechargeable Magnesium Batteries

Advanced Science, EarlyView.
A mixed‐coordination electrolyte (MCE) combined with a molecular additive (MCE‐MA) promotes pseudo ion pair (pIP) formation within a solvent‐separated ion pair (SSIP)–rich environment, enabling a robust interphase that significantly improves the cycle performance of high‐voltage rechargeable magnesium batteries (RMBs).
Dedy Setiawan, Toshihiko Mandai
wiley   +1 more source