Results 11 to 20 of about 22,851 (287)
Tetrahydrobioterin (BH4) pathway: from metabolism to neuropsychiatry.
Current Neuropharmacology, 2020 Tetrahydrobipterin (BH4) is a pivotal enzymatic cofactor required for the synthesis of serotonin, dopamine and nitric oxide. BH4 is essential for numerous physiological processes at periphery and central level, such as vascularization, inflammation ...
H. Fanet +4 more
semanticscholar +7 more sources
Increasing Hydrogen Density with the Cation-Anion Pair BH4−-NH4+ in Perovskite-Type NH4Ca(BH4)3 [PDF]
Energies, 2015 A novel metal borohydride ammonia-borane complex Ca(BH4)2·NH3BH3 is characterized as the decomposition product of the recently reported perovskite-type metal borohydride NH4Ca(BH4)3, suggesting that ammonium-based metal borohydrides release hydrogen gas ...
Pascal Schouwink +4 more
doaj +2 more sources
Hydrogen Desorption in Mg(BH4)2-Ca(BH4)2 System [PDF]
Energies, 2019 Magnesium borohydride, Mg(BH4)2, and calcium borohydride, Ca(BH4)2, are promising materials for hydrogen storage. Mixtures of different borohydrides have been the subject of numerous researches; however, the whole Mg(BH4)2-Ca(BH4)2 system has not been ...
E. Dematteis, M. Baricco
semanticscholar +2 more sources
BH4 treatment in BH4-responsive PKU patients: preliminary data on blood prolactin concentrations suggest increased cerebral dopamine concentrations [PDF]
Molecular Genetics and Metabolism, 2015 In phenylketonuria (PKU), cerebral neurotransmitter deficiencies have been suggested to contribute to brain dysfunction. Present treatment aims to reduce blood phenylalanine concentrations by a phenylalanine-restricted diet, while in some patients blood phenylalanine concentrations also respond to cofactor treatment with tetrahydrobiopterin (BH4 ...
van Vliet, Danique +9 more
openaire +4 more sources
Ca(BH4)2-Mg2NiH4: on the pathway to a Ca(BH4)2 system with a reversible hydrogen cycle. [PDF]
Chemical communications (Cambridge, England), 2016 The Ca(BH4)2-Mg2NiH4 system presented here is, to the best of our knowledge, the first described Ca(BH4)2-based hydride composite that reversibly transfers boron from the Ca-based compound(s) to the reaction partner. The ternary boride MgNi2.5B2 is formed upon dehydrogenation and the formation of Ca(BH4)2 upon rehydrogenation is confirmed.
Bergemann, N +8 more
openaire +6 more sources
Metabolism and regulation of tetrahydrobiopterin and its implications for BH4-responsive hyperphenylalaninemia and BH4-deficiencies [PDF]
, 2008 The autosomal recessive inherited, metabolic disorder phenylketonuria (PKU) is caused by a deficiency of the enzyme phenylalanine hydroxylase (PAH) – a key enzyme in the catabolism of phenylalanine. PKU patients present with noxiously increased concentrations of the amino acid phenylalanine in the plasma, leading to a so-called hyperphenylalaninemia ...
Zurflüh, M R
core +3 more sources
Molecular Genetics and Metabolism Reports, 2015 Background and aims: BH4-sensitive phenylketonuria (PKU) patients relax their phenylalanine (Phe) restricted diet due to increased Phe tolerance, while keeping dried blood Phe concentrations with in the therapeutic range.
Alena G. Thiele +8 more
doaj +2 more sources
Preparation and Characterization of Ti(BH4)3(THF)3 and V(BH4)2(TMEDA)2 Complexes [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 1994 We have recently synthesized Ti(BH4)3(THF)3 and V(BH4)2(TMEDA)2 complexes. The reaction of TiCl3(THF)3 with NaBH4 in dry THF gave flat blue crystals, Ti(BH4)3(THF)3. The reaction of VCl3 with NaBH4 in presence of N, N, N', N'- tetramethylethylenediamine,
Hossein Aghabozorg, Robabeh Alizadeh
doaj +1 more source
Current Pharmaceutical Biotechnology, 2011 Understanding and consequently treating neuropathic pain effectively is a challenge for modern medicine, as unlike inflammation, which can be controlled relatively well, chronic pain due to nerve injury is refractory to most current therapeutics. Here we define a target pathway for a new class of analgesics, tetrahydrobiopterin (BH4) synthesis and ...
Alban, Latremoliere, Michael, Costigan
openaire +2 more sources
Crystallographic characterization of (C5H4SiMe3)3U(BH4) [PDF]
, 2021 New syntheses have been developed for the synthesis of (borohydrido-κ3 H)tris-[η5-(tri-methyl-sil-yl)cyclo-penta-dien-yl]uranium(IV), [U(BH4)(C8H13Si)3] or Cp'3U(BH4) (Cp' = C5H4SiMe3) and its structure has been determined by single-crystal X-ray ...
Kozimor, Stosh A +9 more
core +1 more source