Results 31 to 40 of about 41,817 (145)

bHLH Genes and Retinal Cell Fate Specification [PDF]

Molecular Neurobiology, 2005
The various cell types in the vertebrate retina arise from a pool of common progenitors. The way that the cell types are specified has been a long-standing issue. Decades of research have yielded a large body of information regarding the involvement of extrinsic factors, and only recently has the function of intrinsic factors begun to emerge.
Run-Tao, Yan, Wenxin, Ma, Lina, Liang, Shu-Zhen, Wang   +3 more
openaire   +2 more sources

Assembly and function of bHLH–PAS complexes [PDF]

Proceedings of the National Academy of Sciences, 2017
The basic helix–loop–helix-PER-ARNT-SIM (bHLH–PAS) family of transcription factors coordinates the expression of distinct transcriptional programs to control processes from development to the hypoxia response and beyond. Despite differences in their target genes and modes of regulation, these transcription factors share a common domain architecture ...
Jennifer L, Fribourgh, Carrie L, Partch
openaire   +2 more sources

A note on the nomenclatural representation of plant transcription factors, and deviations thereof

The EuroBiotech Journal
Plant transcription factors (TFs) are integral proteins associated with gene transcription. That ability arises after TFs bind to specific DNA sequences, such as promoters, responding positively or negatively to a multitude of endogenous and exogenous ...
Teixeira da Silva Jaime A.
doaj   +1 more source

Transcription factor TCF4: structure, function, and associated diseases

Вавиловский журнал генетики и селекции
Our understanding of human genes - particularly their structure, functions, and regulatory mechanisms - is still limited. The biological role of approximately 20 % of human proteins has not been established yet, and the molecular functions of the known ...
R. R. Savchenko, N. A. Skryabin
doaj   +1 more source

Genome-wide identification and expression analysis of the bHLH transcription factor family and its response to abiotic stress in sorghum [Sorghum bicolor (L.) Moench]

BMC Genomics, 2021
Background Basic helix-loop-helix (bHLH) is a superfamily of transcription factors that is widely found in plants and animals, and is the second largest transcription factor family in eukaryotes after MYB.
Yu Fan, Hao Yang, Dili Lai, Ailing He, Guoxing Xue, Liang Feng, Long Chen, Xiao-bin Cheng, Jingjun Ruan, Jun Yan, Jianping Cheng   +10 more
doaj   +1 more source

Early evolution of bHLH proteins in plants [PDF]

Plant Signaling & Behavior, 2010
Basic-helix-loop-helix (bHLH) proteins are a large family of eukaryotic transcription factors. In plants, they have been shown to be key regulators of a diverse array of developmental and metabolic pathways. We have recently shown that the diversity of bHLH proteins in angiosperms is ancient.
Pires, N, Dolan, L
openaire   +3 more sources

Investigations of the CLOCK and BMAL1 Proteins Binding to DNA: A Molecular Dynamics Simulation Study. [PDF]

PLoS ONE, 2016
The circadian locomotor output cycles kaput (CLOCK), and brain and muscle ARNT-like 1 (BMAL1) proteins are important transcriptional factors of the endogenous circadian clock.
Tuo Xue, Chunnian Song, Qing Wang, Yan Wang, Guangju Chen   +4 more
doaj   +1 more source

The Basic/Helix-Loop-Helix Protein Family in Gossypium: Reference Genes and Their Evolution during Tetraploidization.

PLoS ONE, 2015
Basic/helix-loop-helix (bHLH) proteins comprise one of the largest transcription factor families and play important roles in diverse cellular and molecular processes.
Qian Yan, Hou-Sheng Liu, Dan Yao, Xin Li, Han Chen, Yang Dou, Yi Wang, Yan Pei, Yue-Hua Xiao   +8 more
doaj   +1 more source

A genome-wide survey on basic helix-loop-helix transcription factors in giant panda.

PLoS ONE, 2011
The giant panda (Ailuropoda melanoleuca) is a critically endangered mammalian species. Studies on functions of regulatory proteins involved in developmental processes would facilitate understanding of specific behavior in giant panda.
Chunwang Dang, Yong Wang, Debao Zhang, Qin Yao, Keping Chen   +4 more
doaj   +1 more source

Genome-Wide Identification and Characterization of bHLH Transcription Factors Related to Anthocyanin Biosynthesis in Red Walnut (Juglans regia L.)

Frontiers in Genetics, 2021
Basic helix-loop-helix (bHLH) proteins are transcription factors (TFs) that have been shown to regulate anthocyanin biosynthesis in many plant species. However, the bHLH gene family in walnut (Juglans regia L.) has not yet been reported.
Wei Zhao, Wei Zhao, Yonghui Liu, Yonghui Liu, Lin Li, Lin Li, Haijun Meng, Haijun Meng, Ying Yang, Ying Yang, Zhaobin Dong, Lei Wang, Lei Wang, Guoliang Wu, Guoliang Wu   +14 more
doaj   +1 more source