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Comparison of decision tree with common machine learning models for prediction of biguanide and sulfonylurea poisoning in the United States: an analysis of the National Poison Data System [PDF]
BMC Medical Informatics and Decision Making, 2023 Background Biguanides and sulfonylurea are two classes of anti-diabetic medications that have commonly been prescribed all around the world. Diagnosis of biguanide and sulfonylurea exposures is based on history taking and physical examination; thus ...
Omid Mehrpour +6 more
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Scientific Reports, 2021 To develop antitumor drugs capable of targeting energy metabolism in the tumor microenvironment, we produced a series of potent new biguanide derivatives via structural modification of the arylbiguanide scaffold.
Takayuki Sakai +6 more
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Biguanides antithetically regulate tumor properties by the dose-dependent mitochondrial reprogramming-driven c-Src pathway [PDF]
Cell Reports MedicineSummary: The biguanide metformin attenuates mitochondrial oxidation and is proposed as an anti-cancer therapy. However, recent clinical studies suggest increased proliferation and fatty acid β-oxidation (FAO) in a subgroup of patients with breast cancer (
Jun Hyoung Park +25 more
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Contact allergy to polyhexamethylene biguanide (polyaminopropyl biguanide) [PDF]
Contact Dermatitis, 2020 AbstractBackgroundPolyaminopropyl biguanide (INCI name) and polyhexamethylene biguanide (PHMB) are polymeric biguanides. PHMB is a broad‐spectrum antimicrobial substance used as a preservative in many products. Due to our limited knowledge on PHMB contact allergy frequency and the fact that cases of allergic contact dermatitis to PHMB might be missed ...
Thanisorn Sukakul +9 more
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Frontiers in Medicine, 2022 ObjectiveDiabetes mellitus (DM) is associated with immune dysregulation, while sulfonylureas or biguanides have been linked to anti-inflammatory mechanisms.
Yu-Jih Su +7 more
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Genotyping panel to assess Hand-Foot Syndrome in T2DM and cancer patients who receive concurrent Platin derivates and Biguanides [PDF]
World Cancer Research Journal, 2020 Objective: Different prevention strategies towards Type II Diabetes Mellitus (T2DM) patients with neuromuscular pain have been assessed in several studies.
A. Licito +8 more
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Biological Properties of Transition Metal Complexes with Metformin and Its Analogues
Pharmaceuticals, 2022 Metformin is a widely prescribed medication for the treatment and management of type 2 diabetes. It belongs to a class of biguanides, which are characterized by a wide range of diverse biological properties, including anticancer, antimicrobial ...
Daniil A. Rusanov +2 more
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As biguanidas na terapêutica da diabetes.
Acta Médica Portuguesa, 1989 Biguanides are useful drugs in diabetes but their indications are very precise. The danger of lactic acidosis can be avoided with the use of metformin, the less toxic of biguanides, and strict respect for contraindications.
A M Saraiva
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Pharmacogenetics of Anti-Diabetes Drugs
Pharmaceuticals, 2010 A variety of treatment modalities exist for individuals with type 2 diabetes mellitus (T2D). In addition to dietary and physical activity interventions, T2D is also treated pharmacologically with nine major classes of approved drugs.
Johanna K. DiStefano +1 more
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