Results 11 to 20 of about 22,636 (317)
Synthetic accesses to biguanide compounds [PDF]
Beilstein Journal of Organic Chemistry, 2021 Biguanide is a unique chemical function, which has attracted much attention a century ago and is showing resurgent interest in recent years after a long period of dormancy.
Oleksandr Grytsai +2 more
doaj +5 more sources
Comparing the effects of biguanides and dipeptidyl peptidase-4 inhibitors on cardio-cerebrovascular outcomes, nephropathy, retinopathy, neuropathy, and treatment costs in diabetic patients. [PDF]
PLoS ONEBackgroundWestern guidelines often recommend biguanides as the first-line treatment for diabetes. However, dipeptidyl peptidase-4 (DPP-4) inhibitors, alongside biguanides, are increasingly used as the first-line therapy for type 2 diabetes (T2DM) in ...
Eiji Nakatani +14 more
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Journal of Medical Microbiology, 2016 In this study, polyaminopropyl biguanide (PAPB) was compared to the molecularly closely related polyhexamethylene biguanide (PHMB) with respect to chemical relationship, antiseptic efficacy and cytotoxicity in vitro. Cytotoxicity for human keratinocytes (
J. Rembe +4 more
semanticscholar +4 more sources
Acta Pharmaceutica, 2018 Extensive in vitro studies have been conducted to evaluate the anticancer activity of oral hypoglycemic agents. Many of these studies experienced detrimental limitations, since they were conducted on cancer cells commonly grown in culture media ...
Bardaweel Sanaa K. +3 more
doaj +2 more sources
Zur Kenntnis der Biguanide [PDF]
Journal für Praktische Chemie, 1911 n ...
Georg Cohn
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International Journal of Environmental Research and Public Health, 2023 Patient data from the National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB) are used to assess the effect of biguanide administration on rates of lactic acidosis (LA) in hospitalized diabetes mellitus (DM) patients.
Takako Mohri +10 more
semanticscholar +1 more source
Contact allergy to polyhexamethylene biguanide (polyaminopropyl biguanide) [PDF]
Contact Dermatitis, 2020 AbstractBackgroundPolyaminopropyl biguanide (INCI name) and polyhexamethylene biguanide (PHMB) are polymeric biguanides. PHMB is a broad‐spectrum antimicrobial substance used as a preservative in many products. Due to our limited knowledge on PHMB contact allergy frequency and the fact that cases of allergic contact dermatitis to PHMB might be missed ...
Cecilia Svedman +10 more
openaire +3 more sources
The Mechanism of Action of Biguanides: New Answers to a Complex Question
Cancers, 2022 Simple Summary In the last two decades, the antidiabetic drugs, biguanides, have received considerable interest owing to their presumed antitumor properties.
Laura Di Magno +4 more
semanticscholar +1 more source
Genotyping panel to assess Hand-Foot Syndrome in T2DM and cancer patients who receive concurrent Platin derivates and Biguanides [PDF]
World Cancer Research Journal, 2020 Objective: Different prevention strategies towards Type II Diabetes Mellitus (T2DM) patients with neuromuscular pain have been assessed in several studies.
A. Licito +8 more
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Biological Properties of Transition Metal Complexes with Metformin and Its Analogues
Pharmaceuticals, 2022 Metformin is a widely prescribed medication for the treatment and management of type 2 diabetes. It belongs to a class of biguanides, which are characterized by a wide range of diverse biological properties, including anticancer, antimicrobial ...
Daniil A. Rusanov +2 more
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