Results 11 to 20 of about 9,884 (217)

Pleiotropic Activity of Metformin and Its Sulfonamide Derivatives on Vascular and Platelet Haemostasis

Molecules, 2019
As type 2 diabetes mellitus (T2DM) predisposes patients to endothelial cell injury and dysfunction, improvement of vascular function should be an important target for therapy.
Magdalena Markowicz-Piasecka, Kristiina M. Huttunen, Adrianna Sadkowska, Joanna Sikora   +3 more
doaj   +1 more source

Metformin in the treatment of breast cancer among patients with metabolic syndrome

Опухоли женской репродуктивной системы, 2015
Breast cancer (BC) is one of the most common cancer among women worldwide. In 2005, the International Diabetes Federation (International Diabetes Federation) declared metabolic syndrome is one of the main problems of modern medicine, as it increases the ...
R. V. Lyubota
doaj   +1 more source

Caracterização microbiológica e clínica de surtos de "red leg" em Minas Gerais e avaliação do efeito bactericida in vitro do Vantocil IB® para Aeromonas hydrophila Microbiological and clinical characterization of "red leg" outbreaks in Minas Gerais, Brazil, and evaluation of in vitro bacterial effects of Vantocil IB® for Aeromonas hydrophila

Ciência Rural, 2000
Com o objetivo da caracterização da ocorrência de "red leg" em Minas Gerais, avaliaram-se rãs jovens e adultas que apresentavam úlceras nas patas e dedos, derrame hemorrágico na pele da região ventral, incoordenação motora, altas taxas de mortalidade em ...
Anna Christina de Almeida, Luiz Eduardo Ristow, Tânia de Toledo Martins Buelta   +2 more
doaj   +1 more source

A Review on Recent Advancement on Age-Related Hearing Loss: The Applications of Nanotechnology, Drug Pharmacology, and Biotechnology

Pharmaceutics, 2021
Aging is considered a contributing factor to many diseases such as cardiovascular disease, Alzheimer’s disease, and hearing loss. Age-related hearing loss, also termed presbycusis, is one of the most common sensory impairments worldwide, affecting one in
Jacqueline Chester, Edan Johnston, Daniel Walker, Melissa Jones, Corina Mihaela Ionescu, Susbin Raj Wagle, Božica Kovacevic, Daniel Brown, Momir Mikov, Armin Mooranian, Hani Al-Salami   +10 more
doaj   +1 more source

Mono- and Dinuclear Aluminium Complexes Derived from Biguanide and Carbothiamide Ligands

Inorganics, 2021
Dianionic N,N-chelating ligands play a crucial role in coordination chemistry, but reports on related complexes remain limited to certain types of ligands.
Maximilian Dehmel, Helmar Görls, Robert Kretschmer   +2 more
doaj   +1 more source

Does atorvastatin work more effectively than biguanides in reducing cardiovascular risk factors?

Journal of Pharmacy and Bioallied Sciences, 2011
Increased risk of coronary artery disease in diabetic persons is associated with increased level of lipoproteins. Usually, such risks are reverted with glycemic control by antidiabetic medicines in Type I diabetes millitus.
Afshan Siddiq, Rafeeq Alam Khan, Sadia Ghousia Baig   +2 more
doaj   +1 more source

Noninsulin pharmacological management of type 1 diabetes mellitus

Indian Journal of Endocrinology and Metabolism, 2011
The injectable nature and other shortcomings of insulin have stimulated interest in studying the noninsulin pharmacological therapies to manage type 1 diabetes mellitus (T1DM).
Vishvas Garg
doaj   +1 more source

Natural Products to Counteract the Epidemic of Cardiovascular and Metabolic Disorders

Molecules, 2016
Natural products have always been exploited to promote health and served as a valuable source for the discovery of new drugs. In this review, the great potential of natural compounds and medicinal plants for the treatment or prevention of cardiovascular ...
Birgit Waltenberger, Andrei Mocan, Karel Šmejkal, Elke H. Heiss, Atanas G. Atanasov   +4 more
doaj   +1 more source

Ether lipid biosynthesis promotes lifespan extension and enables diverse pro-longevity paradigms in Caenorhabditis elegans

eLife, 2023
Biguanides, including the world’s most prescribed drug for type 2 diabetes, metformin, not only lower blood sugar, but also promote longevity in preclinical models.
Lucydalila Cedillo, Fasih M Ahsan, Sainan Li, Nicole L Stuhr, Yifei Zhou, Yuyao Zhang, Adebanjo Adedoja, Luke M Murphy, Armen Yerevanian, Sinclair Emans, Khoi Dao, Zhaozhi Li, Nicholas D Peterson, Jeramie Watrous, Mohit Jain, Sudeshna Das, Read Pukkila-Worley, Sean P Curran, Alexander A Soukas   +18 more
doaj   +1 more source

Genotypic and Phenotypic Factors Influencing Drug Response in Mexican Patients With Type 2 Diabetes Mellitus

Frontiers in Pharmacology, 2018
The treatment of Type 2 Diabetes Mellitus (T2DM) consists primarily of oral antidiabetic drugs (OADs) that stimulate insulin secretion, such as sulfonylureas (SUs) and reduce hepatic glucose production (e.g., biguanides), among others.
Hector E. Sanchez-Ibarra, Luisa M. Reyes-Cortes, Xian-Li Jiang, Claudia M. Luna-Aguirre, Dionicio Aguirre-Trevino, Ivan A. Morales-Alvarado, Rafael B. Leon-Cachon, Fernando Lavalle-Gonzalez, Faruck Morcos, Faruck Morcos, Hugo A. Barrera-Saldaña, Hugo A. Barrera-Saldaña   +11 more
doaj   +1 more source