Frontiers in Medicine, 2022 ObjectiveDiabetes mellitus (DM) is associated with immune dysregulation, while sulfonylureas or biguanides have been linked to anti-inflammatory mechanisms.
Yu-Jih Su +7 more
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Genotyping panel to assess Hand-Foot Syndrome in T2DM and cancer patients who receive concurrent Platin derivates and Biguanides [PDF]
World Cancer Research Journal, 2020 Objective: Different prevention strategies towards Type II Diabetes Mellitus (T2DM) patients with neuromuscular pain have been assessed in several studies.
A. Licito +8 more
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Biological Properties of Transition Metal Complexes with Metformin and Its Analogues
Pharmaceuticals, 2022 Metformin is a widely prescribed medication for the treatment and management of type 2 diabetes. It belongs to a class of biguanides, which are characterized by a wide range of diverse biological properties, including anticancer, antimicrobial ...
Daniil A. Rusanov +2 more
doaj +1 more source
The welfare impact of parallel imports: A structural approach applied to the German market for oral anti-diabetics [PDF]
, 2014 We investigate the welfare impact of parallel imports using a large panel data set containing monthly information on sales, ex-factory prices, and further product characteristics for all 700 anti-diabetic drugs sold in Germany between 2004 and 2010.
Duso, Tomaso +2 more
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Metformin induces distinct bioenergetic and metabolic profiles in sensitive versus resistant high grade serous ovarian cancer and normal fallopian tube secretory epithelial cells. [PDF]
, 2017 Metformin is a widely used agent for the treatment of diabetes and infertility, however, it has been found to have anti-cancer effects in a variety of malignancies including high grade serous ovarian cancer (HGSC).
Aspuria, Paul-Joseph P +6 more
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As biguanidas na terapêutica da diabetes.
Acta Médica Portuguesa, 1989 Biguanides are useful drugs in diabetes but their indications are very precise. The danger of lactic acidosis can be avoided with the use of metformin, the less toxic of biguanides, and strict respect for contraindications.
A M Saraiva
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Molecular features of biguanides required for targeting of mitochondrial respiratory complex I and activation of AMP-kinase. [PDF]
, 2016 BACKGROUND: The biguanides are a family of drugs with diverse clinical applications. Metformin, a widely used anti-hyperglycemic biguanide, suppresses mitochondrial respiration by inhibiting respiratory complex I. Phenformin, a related anti-hyperglycemic
Agip, Ahmed-Noor A +3 more
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The effect of concomitant DPPIVi use on glycaemic control and hypoglycaemia with insulin glargine 300 U/mL (Gla-300) versus insulin glargine 100 U/mL (Gla-100) in people with type 2 diabetes: A patient-level meta-analysis of EDITION 2 and 3 [PDF]
, 2018 Aims To evaluate the effect of concomitant dipeptidyl peptidase IV inhibitor (DPPIVi) use on efficacy and safety of insulin glargine 300 U/mL (Gla-300) versus glargine 100 U/mL (Gla-100) in people with type 2 diabetes on oral antihyperglycaemic drugs ...
Yale, Jean-François +7 more
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Pharmacogenetics of Anti-Diabetes Drugs
Pharmaceuticals, 2010 A variety of treatment modalities exist for individuals with type 2 diabetes mellitus (T2D). In addition to dietary and physical activity interventions, T2D is also treated pharmacologically with nine major classes of approved drugs.
Johanna K. DiStefano +1 more
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Editorial:Metformin: Beyond Diabetes [PDF]
, 2019 International ...
Bost +19 more
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