Results 11 to 20 of about 207,201 (166)

A simple and accurate HPLC method for fecal bile acid profile in healthy and cirrhotic subjects: validation by GC-MS and LC-MS[S]

Journal of Lipid Research, 2014
We have developed a simple and accurate HPLC method for measurement of fecal bile acids using phenacyl derivatives of unconjugated bile acids, and applied it to the measurement of fecal bile acids in cirrhotic patients.
Genta Kakiyama, Akina Muto, Hajime Takei, Hiroshi Nittono, Tsuyoshi Murai, Takao Kurosawa, Alan F. Hofmann, William M. Pandak, Jasmohan S. Bajaj   +8 more
doaj   +1 more source

Bile acid patterns in commercially available oxgall powders used for the evaluation of the bile tolerance ability of potential probiotics. [PDF]

PLoS ONE, 2018
This study aimed to analyze the bile acid patterns in commercially available oxgall powders used for evaluation of the bile tolerance ability of probiotic bacteria.
Peng-Li Hu, Ya-Hong Yuan, Tian-Li Yue, Chun-Feng Guo   +3 more
doaj   +1 more source

The ‘in vivo lifestyle’ of bile acid 7α-dehydroxylating bacteria: comparative genomics, metatranscriptomic, and bile acid metabolomics analysis of a defined microbial community in gnotobiotic mice

Gut Microbes, 2020
The formation of secondary bile acids by gut microbes is a current topic of considerable biomedical interest. However, a detailed understanding of the biology of anaerobic bacteria in the genus Clostridium that are capable of generating secondary bile ...
Jason M. Ridlon, Saravanan Devendran, João Mp Alves, Heidi Doden, Patricia G. Wolf, Gabriel V. Pereira, Lindsey Ly, Alyssa Volland, Hajime Takei, Hiroshi Nittono, Tsuyoshi Murai, Takao Kurosawa, George E. Chlipala, Stefan J. Green, Alvaro G. Hernandez, Christopher J. Fields, Christy L. Wright, Genta Kakiyama, Isaac Cann, Purna Kashyap, Vance McCracken, H. Rex Gaskins   +21 more
doaj   +1 more source

The economy of the enterohepatic circulation of bile acids in the baboon. 2. Regulation of bile acid synthesis by enterohepatic circulation of bile acids.

Journal of Lipid Research, 1984
Isotope dilution within bile acid pools and radiochemical assessment of cholesterol oxidation to bile acids were methods used to measure short-term feedback regulation of bile acid synthesis in baboons with controlled enterohepatic circulations ...
R N Redinger
doaj   +1 more source

Bile Acids in Porcine Fetal Bile.

Biological and Pharmaceutical Bulletin, 2000
A study of the biliary bile acid composition in porcine fetus compared with that of the adult pig is described. Biles, collected during gestation (weeks 4, 15 to 17 and at birth), aged six months and two years old, were analyzed by gas-liquid chromatography and capillary GC-MS. Bile acids were separated into different conjugate groups by chromatography
KURAMOTO, Taiju, MIYAMOTO, Junko, KONISHI, Masaki, HOSHITA, Takahiko, MASUI, Takako, UNE, Mizuho   +5 more
openaire   +3 more sources

Hepatic bile acid uptake: effect of conjugation, hydroxyl and keto groups, and albumin binding

Journal of Lipid Research, 1982
Hepatic extraction of trihydroxy (free, glyco- and tauro-conjugated) dihydroxy, and monohydroxy bile acids has been evaluated in single pass liver perfusion experiments in rats.
R Aldini, A Roda, A M Labate, G Cappelleri, E Roda, L Barbara   +5 more
doaj   +1 more source

Diversification of host bile acids by members of the gut microbiota

Gut Microbes, 2020
Bile acid biotransformation is a collaborative effort by the host and the gut microbiome. Host hepatocytes synthesize primary bile acids from cholesterol.
Jenessa A. Winston, Casey M. Theriot
doaj   +1 more source

Recent advances in understanding bile acid homeostasis [version 1; referees: 2 approved]

F1000Research, 2017
Bile acids are derived from cholesterol to facilitate intestinal nutrient absorption and biliary secretion of cholesterol. Recent studies have identified bile acids as signaling molecules that activate nuclear farnesoid X receptor (FXR) and membrane G ...
John YL Chiang
doaj   +1 more source

Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases

Frontiers in Medicine, 2020
In the past ten years, our understanding of the importance of bile acids has expanded from fat absorption and glucose/lipid/energy homeostasis into potential therapeutic targets for amelioration of chronic cholestatic liver diseases.
Vik Meadows, Vik Meadows, Lindsey Kennedy, Debjyoti Kundu, Gianfranco Alpini, Gianfranco Alpini, Heather Francis, Heather Francis   +7 more
doaj   +1 more source

Ileal bile acid transport regulates bile acid pool, synthesis, and plasma cholesterol levels differently in cholesterol-fed rats and rabbits

Journal of Lipid Research, 2000
We investigated the effect of ileal bile acid transport on the regulation of classic and alternative bile acid synthesis in cholesterol-fed rats and rabbits.
Guorong Xu, Benjamin L. Shneider, Sarah Shefer, Lien B. Nguyen, Ashok K. Batta, G. Stephen Tint, Marco Arrese, Sundararajah Thevananther, Lin Ma, Siegfried Stengelin, Werner Kramer, David Greenblatt, Mark Pcolinsky, Gerald Salen   +13 more
doaj   +1 more source