Results 31 to 40 of about 207,201 (166)
Endoplasmic Reticulum Stress Regulates Hepatic Bile Acid Metabolism in MiceSummary
Cellular and Molecular Gastroenterology and Hepatology, 2017 Background & Aims: Cholestasis promotes endoplasmic reticulum (ER) stress in the liver, however, the effect of ER stress on hepatic bile acid metabolism is unknown.
Anne S. Henkel +3 more
doaj +1 more source
mSystems, 2021 Gut bacteria influence human physiology by chemically modifying host-synthesized primary bile acids. These modified bile acids, known as secondary bile acids, can act as signaling molecules that modulate host lipid, glucose, and energy metabolism and ...
L. N. Lucas +7 more
doaj +1 more source
Journal of Lipid Research, 1992 To further define thyroid hormone effects on bile acid synthesis and biliary lipid secretion, studies were done in chronic bile fistula rats. Euthyroid and methimazole-hypothyroid rats, with and without triiodothyronine (T3) injection, had total bile ...
RL Gebhard, WF Prigge
doaj +1 more source
Hepatology Communications, 2022 Bile acid‐CoA: amino acid N‐acyltransferase (BAAT) catalyzes bile acid conjugation, the last step in bile acid synthesis. BAAT gene mutation in humans results in hypercholanemia, growth retardation, and fat‐soluble vitamin insufficiency.
Bandar D. Alrehaili +15 more
doaj +1 more source
Paclitaxel chemotherapy disrupts microbiota-enterohepatic bile acid metabolism in mice
Gut MicrobesBalanced interactions between the enteric microbiota and enterohepatic organs are essential to bile acid homeostasis, and thus normal gastrointestinal function.
Brett R. Loman +8 more
doaj +1 more source
An N-acyl glycyltaurine conjugate of deoxycholic acid in the biliary bile acids of the rabbit
Journal of Lipid Research, 1998 The biliary bile acid composition of the adult and neonatal domestic rabbit, as well as that of the adult brush rabbit, was characterized. In adult domestic rabbits, the dominant bile acid present was deoxycholic acid (88“% of total bile acids), a ...
Lee R. Hagey +4 more
doaj +1 more source
Biliary lipid secretion in hypercholesterolemia.
Journal of Lipid Research, 1979 A report on the effects of primary bile acid ingestion alone or in combination with plant sterols on serum cholesterol levels, biliary lipid secretion, and bile acid metabolism.
T N Tangedahl, A F Hofmann, B A Kottke
doaj +1 more source
Abnormal bile acid absorption in familial hypertriglyceridemia
Journal of Lipid Research, 1995 To better define the abnormality of bile acid metabolism associated with hypertriglyceridemia, we measured bile acid kinetics and absorption as well as preferential use of newly synthesized cholesterol for bile acid synthesis in eleven controls and ten ...
W C Duane
doaj +1 more source
Annals of Hepatology, 2017 The primary bile acids (BAs) are synthetized from colesterol in the liver, conjugated to glycine or taurine to increase their solubility, secreted into bile, concentrated in the gallbladder during fasting, and expelled in the intestine in response to dietary fat, as well as bio-transformed in the colon to the secondary BAs by the gut microbiota ...
Agostino Di Ciaula +6 more
openaire +4 more sources
Journal of Lipid Research, 1990 Guinea pig gallbladder bile contains chenodeoxycholic acid (62 +/- 5%), ursodeoxycholic acid (8 +/- 5%), and 7-ketolithocholic acid (30 +/- 5%). All three bile acids became labeled to the same specific activity within 30 min after [3H]cholesterol was ...
GS Tint +5 more
doaj +1 more source