Results 11 to 20 of about 2,795,829 (201)

Biosynthesis and biotransformation of bile acids [PDF]

Hospital Pharmacology, 2017
Bile acids are steroidal compounds, which contain 24 carbon atoms. They can be classified into two major groups: primary and secondary. The most abundant bile acids: The primary bile acids include cholic acid and chenodeoxycholic acid, while the major ...
Mikov Momir M., Šarenac Tanja M.
core   +3 more sources

Gut Microbiota-Mediated Elevated Production of Secondary Bile Acids in Chronic Unpredictable Mild Stress

Frontiers in Pharmacology, 2022
A growing body of evidence suggests that gut microbiota could participate in the progression of depression via the microbiota–gut–brain axis. However, the detailed microbial metabolic profile changes in the progression of depression is still not fully ...
Yuchen Qu, Cunjin Su, Qinhong Zhao, Aiming Shi, Fenglun Zhao, Liuxing Tang, Delai Xu, Zheng Xiang, Yang Wang, Yueyuan Wang, Jie Pan, Yunli Yu   +11 more
doaj   +1 more source

Integrated transcriptome and metabolome analysis reveals a possible mechanism for the regulation of lipid metabolism via vitamin A in rice field eel (Monopterus albus)

Frontiers in Physiology, 2023
To understand the effects of vitamin A on lipid deposition in rice field eels, integrated liver transcriptome and metabolome were conducted and the changes in the genes and metabolites were assessed.
Huanhuan Huo, Huanhuan Huo, Chonghua Hu, Qiubai Zhou, Qiubai Zhou, Liufeng Xiong, Liufeng Xiong, Mo Peng, Mo Peng   +8 more
doaj   +1 more source

Effects of Previous Kasai Surgery on Gut Microbiota and Bile Acid in Biliary Atresia With End-Stage Liver Disease

Frontiers in Medicine, 2021
Background and Aims: Biliary atresia (BA) is the most common cholestatic liver disease in neonates. Although the Kasai procedure can improve temporary biliary drainage in some cases, complications and liver fibrosis still develop.
Wei Song, Wei Song, Li-Ying Sun, Li-Ying Sun, Li-Ying Sun, Zhi-Jun Zhu, Zhi-Jun Zhu   +6 more
doaj   +1 more source

Microbiome-Metabolomics Analysis of the Impacts of Cryptosporidium muris Infection in BALB/C Mice

Microbiology Spectrum, 2023
Cryptosporidium is a leading cause of diarrheal disease and mortality in young children worldwide. Cryptosporidium invades small intestinal epithelial cells and forms a unique intracellular niche, a process that may alter gut microbes and their ...
Luyang Wang, Letian Cao, Yankai Chang, Yin Fu, Yuexin Wang, Kaihui Zhang, Sumei Zhang, Longxian Zhang   +7 more
doaj   +1 more source

Biochemical site of regulation of bile acid biosynthesis in the rat

Journal of Lipid Research, 1970
The production of bile salts by rat liver is regulated by a feedback mechanism, but it is not known which enzyme controls endogenous bile acid synthesis.
SARAH SHEFER, SUSAN HAUSER, IHOR BEKERSKY, ERWIN H. MOSBACH   +3 more
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Effects of ursodeoxycholic acid on synthesis of cholesterol and bile acids in healthy subjects [PDF]

, 2004
Background/Aims: Ursodeoxycholic acid ( UDCA) decreases biliary secretion of cholesterol and is therefore used for the dissolution of cholesterol gallstones.
Thiessen, K., Parhofer, K. G., Fischer, S., Sauter, G. H., Jungst, D., Jungst, C.   +5 more
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Application of a novel tool for diagnosing bile acid diarrhoea [PDF]

, 2013
Bile acid diarrhoea (BAD) is a common disease that requires expensive imaging to diagnose. We have tested the efficacy of a new method to identify BAD, based on the detection of differences in volatile organic compounds (VOC) in urine headspace of BAD vs.
Arasaradnam, Ramesh P., Ramesh Arasaradnam, James Covington, Ruth Harbord, Catherine Bailey, Chuka U. Nwokolo, Nicola O'Connell, James Cullis, Chuka Nwokolo, Nathalie Ouaret, Nwokolo, Chuka U., Ramesh P. Arasaradnam, Nicola O\u27Connell, Bardhan, Karna Dev, Eric Westenbrink, Karna D. Bardhan, Bailey, Catherine, Westenbrink, Eric W., James A. Covington, Ouaret, Nathalie, O'Connell, Nicola, Cullis, James, Nigel Williams, Eric W. Westenbrink, Karna Bardhan, Covington, James A., Williams, Nigel, Harbord, Ruth   +27 more
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Biliary secretion and excretion in health and disease: Current concepts

Annals of Hepatology, 2007
Biliary secretion in health and disease is reviewed. The powerful techniques of molecular biology have enabled cloning of the transporters involved in biliary secretion and the enterohepatic circulation of bile acids.
Alan F Hofmann
doaj   +1 more source

A Role of the Bile Salt Receptor FXR in Atherosclerosis [PDF]

, 2010
This study reviews current insights into the role of bile salts and bile salt receptors on the progression and regression of atherosclerosis. Bile salts have emerged as important modifiers of lipid and energy metabolism.
Albert K. Groen, Hageman, Jurre, Herrema, H.J., Folkert Kuipers, Hageman, J., Kuipers, Folkert, Herrema, Hilde, Hilde Herrema, Kuipers, Folkert; id_orcid, Groen, A.K., Kuipers, F., Groen, Albert K., Jurre Hageman   +12 more
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