Results 161 to 170 of about 87,670 (247)

Hepatic miR-378 modulates serum cholesterol levels by regulating hepatic bile acid synthesis. [PDF]

Theranostics, 2021
Sun C, Liu W, Lu Z, Li Y, Liu S, Tang Z, Yan Y, Li Z, Feng H, Zhang D, Liu Y, Fang ZZ, Jiang C, Ding Q, Jiang J, Ying H.   +15 more
europepmc   +1 more source

Bile acid synthesis impedes tumor-specific T cell responses during liver cancer. [PDF]

Science
Varanasi SK, Chen D, Liu Y, Johnson MA, Miller CM, Ganguly S, Lande K, LaPorta MA, Hoffmann FA, Mann TH, Teneche MG, Casillas E, Mangalhara KC, Mathew V, Sun M, Jensen IJ, Farsakoglu Y, Chen T, Parisi B, Deota S, Havas A, Lee J, Chung HK, Schietinger A, Panda S, Williams AE, Farber DL, Dhar D, Adams PD, Feng GS, Shadel GS, Sundrud MS, Kaech SM.   +32 more
europepmc   +1 more source

Restoration of intestinal secondary bile acid synthesis: A potential approach to improve pancreatic β cell function in type 1 diabetes. [PDF]

Cell Rep Med
Liu Q, Hua Y, He R, Xiang L, Li S, Zhang Y, Chen R, Qian L, Jiang X, Wang C, Wang C, Li Y, Wu H, Liu Y.   +13 more
europepmc   +1 more source

The clinical and biochemical effectiveness and safety of cholic acid treatment for bile acid synthesis defects: a systematic review. [PDF]

Orphanet J Rare Dis
Polak Y, van Dussen L, Kemper EM, Vaz FM, Klouwer FCC, Engelen M, Hollak CEM.   +6 more
europepmc   +1 more source

GOLM1 and bile acid synthesis: Correspondence to editorial on "GOLM1 promotes cholesterol gallstone formation via ABCG5-mediated cholesterol efflux in MASH livers". [PDF]

Clin Mol Hepatol
Li YT, Shao WQ, Chen ZM, Lin J, Chen JH.
europepmc   +1 more source

Hepatic SIRT6 protects against cholestatic liver disease primarily <i>via</i> inhibiting bile acid synthesis. [PDF]

J Biomed Res
Zhang W, Wang J, Yang L, Shao Y, Peng H, Jiang L, Sheng L.   +6 more
europepmc   +1 more source

A SYNTHESIS OF CONJUGATED BILE ACIDS

Journal of Biological Chemistry, 1936
Frank Cortese, Louis Bauman
openaire   +1 more source

Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy

iMetaMed, EarlyView.
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia, Guiling Fu, Xiaoyue Ding, Wen Yang, Ruijie Bai, Yawei Cai, Jing xuan Zhang, Yanxia Wei, Conghui Han, Yi‐Zhou Gao, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

Efficacy and safety of switching therapy from chenodeoxycholic acid to cholic acid in Japanese patients with bile acid synthesis disorders. [PDF]

Mol Genet Metab Rep
Suzuki M, Takei H, Suzuki H, Mori J, Sugimoto S, Mizuochi T, Ohtake A, Hayashi H, Kimura A, Nittono H.   +9 more
europepmc   +1 more source

Microbial keystone taxa and metabolic signatures in centenarians regulate intestinal homeostasis during aging

iMeta, EarlyView.
Clostridium scindens and its metabolite indole‐3‐acetic acid (IAA) are identified as a keystone taxon and metabolic signature in centenarians. Clostridium scindens enhances microbial network stability and produces IAA via its own amidase (AMIE) and aldehyde dehydrogenase (ALDH), thus promoting intestinal homeostasis by activating the aryl hydrocarbon ...
Wei‐Chuan Lin, Cui Zhang, He‐Hua Lei, Zheng Cao, Xin Gao, Wen‐Kai Yu, Xin‐Zhi Li, Qing‐Wei Xiang, Zhi‐Wen Zhang, Shi‐Fu Pang, Wei‐Fei Luo, Deng‐Hui Xie, Li‐Min Zhang, Gang Chen   +13 more
wiley   +1 more source