Results 21 to 30 of about 59,410 (160)

Taurocholate is more potent than cholate in suppression of bile salt synthesis in the rat

open access: yesJournal of Lipid Research, 1983
Synthesis of bile salts is regulated through negative feedback inhibition by bile salts returning to the liver. Individual bile salts have not been distinguished with regard to inhibitory potential. We assessed inhibition of bile salt synthesis by either
J M Pries   +3 more
doaj   +1 more source

Cholesterol attenuates cytoprotective effects of phosphatidylcholine against bile salts

open access: yesScientific Reports, 2017
Bile salts have potent detergent properties and damaging effects on cell membranes, leading to liver injury. However, the molecular mechanisms for the protection of hepatocytes against bile salts are not fully understood.
Yoshito Ikeda   +2 more
doaj   +1 more source

Evolutionary diversity of bile salts in reptiles and mammals, including analysis of ancient human and extinct giant ground sloth coprolites

open access: yesBMC Evolutionary Biology, 2010
Background Bile salts are the major end-metabolites of cholesterol and are also important in lipid and protein digestion and in influencing the intestinal microflora.
Hofmann Alan F   +3 more
doaj   +1 more source

Interactions of cationic bile salt derivatives with the ileal bile salt transport system.

open access: yesJournal of Lipid Research, 1975
Previous structure-activity studies of the active ileal bile salt transport system have demonstrated that a single negative charge on the side chain is essential for active transport. Furthermore, mutual inhibition studies between different pairs of bile
A Firpi, J T Walker, L Lack
doaj   +1 more source

Teepol in Substitution for Bile Salts [PDF]

open access: yesJournal of General Microbiology, 1958
When any grade of Teepol, other than Teepol 530, Teepol L or Teepol (without suffix), is used in culture media, the authors recommend that it should first be tested for suitability.
J E, JAMESON, N W, EMBERLEY
openaire   +2 more sources

The Role of the Enterohepatic Circulation of Bile Salts and Nuclear Hormone Receptors in the Regulation of Cholesterol Homeostasis: Bile Salts as Ligands for Nuclear Hormone Receptors

open access: yesCanadian Journal of Gastroenterology, 2003
The coordinated effect of lipid activated nuclear hormone receptors; liver X receptor (LXR), bound by oxysterol ligands and farnesoid X receptor (FXR), bound by bile acid ligands, act as genetic transcription factors to cause feed-forward cholesterol ...
Richard N Redinger
doaj   +1 more source

Effect of bile salts on hepatic phosphatidylcholine synthesis and transport into rat bile

open access: yesJournal of Lipid Research, 1972
The effect of transport of micelle-forming and non-micelle-forming conjugated bile salts on phosphatidylcholine synthesis and transport into bile was studied in the ex vivo perfused rat liver.
David L. Young, Kenneth C. Hanson
doaj   +1 more source

Identification of Novel Bile Salt-Tolerant Genes in Lactobacillus Using Comparative Genomics and Its Application in the Rapid Screening of Tolerant Strains

open access: yesMicroorganisms, 2022
Under bile salt treatment, strains display significant differences in their tolerance ability, suggesting the existence of diverse resistance mechanisms in Lactobacillus; however, the genes involved in this protective process are not fully understood. In
Chunfei Chen   +4 more
doaj   +1 more source

Bile Salts as Semiochemicals in Fish [PDF]

open access: yesChemical Senses, 2014
Bile salts are potent olfactory stimuli in fishes; however the biological functions driving such sensitivity remain poorly understood. We provide an integrative review of bile salts as semiochemicals in fish. First, we present characteristics of bile salt structure, metabolism, and function that are particularly relevant to chemical communication. Bile
Tyler J, Buchinger   +2 more
openaire   +2 more sources

Phenotypic characterization of Lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: pathophysiology of biliary lipid secretion1

open access: yesJournal of Lipid Research, 1999
The inbred C57L strain but not the AKR strain of mice carry Lith genes that determine cholesterol gallstone susceptibility. When C57L mice are fed a lithogenic diet containing 15% fat, 1% cholesterol, and 0.5% cholic acid, gallbladder bile displays rapid
David Q-H. Wang   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy