Results 21 to 30 of about 949,943 (203)

A phylogenetic survey of biliary lipids in vertebrates1,

Journal of Lipid Research, 2005
Biliary lipids (bile salts, phospholipids, cholesterol, plant sterols) were determined in 89 vertebrate species (cartilaginous and bony fish, reptiles, birds, and mammals), and individual phospholipid classes were measured in 35 species.
Antonio Moschetta, Fang Xu, Lee R. Hagey, Gerard P. van Berge-Henegouwen, Karel J. van Erpecum, Jos F. Brouwers, Jonathan C. Cohen, Molly Bierman, Helen H. Hobbs, Joseph H. Steinbach, Alan F. Hofmann   +10 more
doaj   +1 more source

A frequent variant in the human bile salt export pump gene ABCB11 is associated with hepatitis C virus infection, but not liver stiffness in a German population [PDF]

, 2012
Background: The human ATP-binding cassette, subfamily B, member 11 (ABCB11) gene encodes the bile salt export pump, which is exclusively expressed at the canalicular membrane of hepatocytes.
Müllenbach, Roman, Marcin Krawczyk, Weber, Susanne N., Grünhage, Frank, Sarrazin, Christoph, Zimmer, Vincent, Frank Grünhage, Krawczyk, Marcin, Lammert, Frank, Christoph Sarrazin, Roman Müllenbach, Susanne N Weber, Vincent Zimmer, Frank Lammert, Krawczyk Marcin, Weber Susanne N, Sarrazin Christoph, Zimmer Vincent, Müllenbach Roman, Lammert Frank, Grünhage Frank   +20 more
core   +2 more sources

Evolution of substrate specificity for the bile salt transporter ASBT (SLC10A2)[S]

Journal of Lipid Research, 2012
The apical Na+-dependent bile salt transporter (ASBT/SLC10A2) is essential for maintaining the enterohepatic circulation of bile salts. It is not known when Slc10a2 evolved as a bile salt transporter or how it adapted to substantial changes in bile salt ...
Daniël A. Lionarons, James L. Boyer, Shi-Ying Cai   +2 more
doaj   +1 more source

Bile salt signaling and bile salt-based therapies in cardiometabolic disease. [PDF]

Clin Sci (Lond)
Abstract Bile salts have an established role in the emulsification and intestinal absorption of dietary lipids, and their homeostasis is tightly controlled by various transporters and regulators in the enterohepatic circulation. Notably, emerging evidence points toward bile salts as major modulators of cardiometabolic disease (CMD), an ...
Groenen CCJ, Nguyen TA, Paulusma CC, van de Graaf SFJ.   +3 more
europepmc   +3 more sources

Taurocholate is more potent than cholate in suppression of bile salt synthesis in the rat

Journal of Lipid Research, 1983
Synthesis of bile salts is regulated through negative feedback inhibition by bile salts returning to the liver. Individual bile salts have not been distinguished with regard to inhibitory potential. We assessed inhibition of bile salt synthesis by either
J M Pries, A Gustafson, D Wiegand, W C Duane   +3 more
doaj   +1 more source

Bile Salt Hydrolase Catalyses Formation of Amine-Conjugated Bile Acids

, 2023
<p>Data, and codes to generate figures in <strong>Bile Salt Hydrolase Catalyses Formation of Amine-Conjugated Bile Acids .</strong></p ...
Collins, Stephanie L., Patterson, Andrew D., Rimal, Bipin   +2 more
core   +1 more source

Evolutionary diversity of bile salts in reptiles and mammals, including analysis of ancient human and extinct giant ground sloth coprolites

BMC Evolutionary Biology, 2010
Background Bile salts are the major end-metabolites of cholesterol and are also important in lipid and protein digestion and in influencing the intestinal microflora.
Hofmann Alan F, Vidal Nicolas, Hagey Lee R, Krasowski Matthew D   +3 more
doaj   +1 more source

Association between cholesterol-phospholipid vesicles and cholesterol crystals in human gallbladder bile [PDF]

, 1989
Rapid aggregation of cholesterol-phospholipid vesicles in gallbladder bile seems to be the first event in the production of cholesterol crystals, a prerequisite for cholesterol gallstone formation.
Schriever, Carolin Erika, Jüngst, Dieter   +1 more
core   +1 more source

Bile Acid Induced Diarrhoea Pathophysiological and Clinical Aspects [PDF]

, 2008
A common cause for referral to gastroenterologists is chronic watery diarrhoea. Approximately 40% of these patients have idiopathic bile acid malabsorption (BAM) – a condition with unknown aetiology.
Bajor, Antal
core   +1 more source

Cholesterol attenuates cytoprotective effects of phosphatidylcholine against bile salts

Scientific Reports, 2017
Bile salts have potent detergent properties and damaging effects on cell membranes, leading to liver injury. However, the molecular mechanisms for the protection of hepatocytes against bile salts are not fully understood.
Yoshito Ikeda, Shin-ya Morita, Tomohiro Terada   +2 more
doaj   +1 more source