Results 31 to 40 of about 158,672 (304)
BMC Evolutionary Biology, 2010 Background Bile salts are the major end-metabolites of cholesterol and are also important in lipid and protein digestion and in influencing the intestinal microflora.
Hofmann Alan F +3 more
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Cholesterol attenuates cytoprotective effects of phosphatidylcholine against bile salts
Scientific Reports, 2017 Bile salts have potent detergent properties and damaging effects on cell membranes, leading to liver injury. However, the molecular mechanisms for the protection of hepatocytes against bile salts are not fully understood.
Yoshito Ikeda +2 more
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Interactions of cationic bile salt derivatives with the ileal bile salt transport system.
Journal of Lipid Research, 1975 Previous structure-activity studies of the active ileal bile salt transport system have demonstrated that a single negative charge on the side chain is essential for active transport. Furthermore, mutual inhibition studies between different pairs of bile
A Firpi, J T Walker, L Lack
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Ligand entry in human ileal bile acid-binding protein is mediated by histidine protonation [PDF]
, 2019 Human ileal bile acid-binding protein (hI-BABP) has a key role in the intracellular transport of bile salts. To explore the role of histidine protonation in the binding process, the pH-dependence of bile salt binding and internal dynamics in hI-BABP was ...
Egyed, Orsolya +6 more
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A frequent variant in the human bile salt export pump gene ABCB11 is associated with hepatitis C virus infection, but not liver stiffness in a German population [PDF]
, 2012 Background: The human ATP-binding cassette, subfamily B, member 11 (ABCB11) gene encodes the bile salt export pump, which is exclusively expressed at the canalicular membrane of hepatocytes.
Grünhage, Frank +6 more
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Kinetics of formation of bile salt micelles from coarse-grained Langevin dynamics simulations. [PDF]
, 2016 We examine the mechanism of formation of micelles of dihydroxy bile salts using a coarse-grained, implicit solvent model and Langevin dynamics simulations.
Frenkel, Daan, Vila Verde, Ana
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Canadian Journal of Gastroenterology, 2003 The coordinated effect of lipid activated nuclear hormone receptors; liver X receptor (LXR), bound by oxysterol ligands and farnesoid X receptor (FXR), bound by bile acid ligands, act as genetic transcription factors to cause feed-forward cholesterol ...
Richard N Redinger
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Effect of bile salts on hepatic phosphatidylcholine synthesis and transport into rat bile
Journal of Lipid Research, 1972 The effect of transport of micelle-forming and non-micelle-forming conjugated bile salts on phosphatidylcholine synthesis and transport into bile was studied in the ex vivo perfused rat liver.
David L. Young, Kenneth C. Hanson
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Studies on Bile Pigments II. Seperation of Natural Direct Bilirubins [PDF]
, 1956 Separation of both forms of the direct bilirubin were carried out from the dog's gallbladder bile, and further isolations of them were also done. 1. The natural salt-form bilirubin was isolated after separation on the column of aluminium oxide with a n ...
Sakamoto, Takeshi
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Microorganisms, 2022 Under bile salt treatment, strains display significant differences in their tolerance ability, suggesting the existence of diverse resistance mechanisms in Lactobacillus; however, the genes involved in this protective process are not fully understood. In
Chunfei Chen +4 more
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