Results 61 to 70 of about 949,943 (203)

Mechanistic insights into the inhibition of NTCP by myrcludex B

open access: yesJHEP Reports, 2019
Background & aims: The sodium taurocholate co-transporting polypeptide (NTCP) is the entry receptor for the hepatitis B and delta virus (HBV/HDV) and the main hepatic uptake transporter of conjugated bile acids. Myrcludex B, a synthetic peptide mimicking
Joanne M. Donkers   +2 more
doaj   +1 more source

Equilibrium Study on Interactions between Proteins and Bile-Salt Micelles by Micellar Electrokinetic Chromatography [PDF]

open access: yes, 1996
Interactions between proteins and bile-salt micelles were evaluated on the basis of the binding constants, which were obtained from the migration of proteins in micellar electrokinetic chromatography. The binding constants, Kb=[Pb]/ ([Pw][B]), where [Pb]
SAITOH, Tohru   +4 more
core   +1 more source

The hydrophobic-hydrophilic balance of bile salts. Inverse correlation between reverse-phase high performance liquid chromatographic mobilities and micellar cholesterol-solubilizing capacities.

open access: yesJournal of Lipid Research, 1982
To examine quantitatively the hydrophobic-hydrophilic properties of bile salts, we determined the reverse-phase high performance liquid chromatographic (HPLC) mobilities of monomeric bile salt solutions and the equilibrium cholesterol-solubilizing ...
M J Armstrong, M C Carey
doaj   +1 more source

Bile salt-dependent inhibition of gallbladder emptying

open access: yes, 1995
Little is known about the inhibitory controls of gallbladder emptying. Since cholestyramine, a binding agent that reduces luminal concentration of bile salt, has been reported to accelerate gallbladder emptying, suggesting that bile salt is inhibitory ...
X. T. Zhao   +4 more
core   +1 more source

Mathematical model of biliary lipid secretion: a quantitative analysis of physiological and biochemical data from man and other species.

open access: yesJournal of Lipid Research, 1984
We propose a simple mathematical model to account for the coupling of secretion rates of bile salts, lecithin, and cholesterol into bile. The model assumes that: 1) molecules of ''biliary'' lecithin and cholesterol enter a functional compartment located ...
N A Mazer, M C Carey
doaj   +1 more source

Bile salt deconjugation ability, bile salt hydrolase activity and cholesterol co-precipitation ability of lactobacilli strains

open access: yes, 2005
Eleven strains of lactobacilli were screened for their bile salt deconjugation ability, bile salt hydrolase activity (BSH) and co-precipitation of cholesterol with deconjugated bile.
Liong, MT, Shah, NP
core   +1 more source

Role of the hepatocyte microtubular system in the excretion of bile salts and biliary lipid: implications for intracellular vesicular transport.

open access: yesJournal of Lipid Research, 1988
The role of the hepatocyte microtubular system in the transport and excretion of bile salts and biliary lipid has not been defined. In this study the effects of microtubule inhibition on biliary excretion of micelle- and non-micelle-forming bile salts ...
J M Crawford, C A Berken, J L Gollan
doaj   +1 more source

The phosphatidylethanolamine N-methyltransferase pathway is quantitatively not essential for biliary phosphatidylcholine secretion

open access: yesJournal of Lipid Research, 2007
The phosphatidylethanolamine N-methyltransferase (PEMT) pathway of phosphatidylcholine (PC) biosynthesis is not essential for the highly specific acyl chain composition of biliary PC.
Henkjan J. Verkade   +7 more
doaj   +1 more source

Hepatic Transport of Bile Salts

open access: yesSeminars in Liver Disease, 2000
The vectorial secretion of bile salts from blood into bile is a major driving force for bile formation. The basolateral hepatocyte membrane extracts bile salts from sinusoidal blood via Na(+)-dependent and Na(+)-independent membrane transporters. Na(+)-dependent uptake of bile salts is mediated by the Na(+)-taurocholate co-transporting polypeptide, a ...
Kullak-Ublick, G. A.   +3 more
openaire   +3 more sources

Bile Esculin and Salt Broth_E faecalis

open access: yes, 2020
Enterococcus faecalis: (left) bile esculin slant – positive; (right) 6.5% salt broth – positivehttps://commons.und.edu/mbio-lab-images/1019/thumbnail ...
Sletten, Sarah
core   +1 more source

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