Results 11 to 20 of about 1,488,373 (296)
Galactoside-Binding Site in LacY [PDF]
Biochemistry, 2014 Although an X-ray crystal structure of lactose permease (LacY) has been presented with bound galactopyranoside, neither the sugar nor the residues ligating the sugar can be identified with precision at ~3.5 Å. Therefore, additional evidence is important for identifying side chains likely to be involved in binding.
Jiang, Xiaoxu +4 more
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Computing the protein binding sites [PDF]
BMC Bioinformatics, 2011 Identifying the location of binding sites on proteins is of fundamental importance for a wide range of applications including molecular docking, de novo drug design, structure identification and comparison of functional sites. Structural genomic projects are beginning to produce protein structures with unknown functions.
Guo, Fei, Wang, Lusheng
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Journal of Lipid Research, 1972 Quantitative aspects of the binding of free fatty acid to human erythrocytes were studied by measuring the distribution of various amounts of [1-14C]lauric acid between washed human erythrocytes and defatted human plasma albumin. Incubations were done at
Arthur A. Spector +3 more
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Diversity of molecular targets and signaling pathways for CBD
Pharmacology Research & Perspectives, 2020 Cannabidiol (CBD) is the second most abundant component of the Cannabis plant and is known to have effects distinct from Δ9‐tetrahydrocannabinol (THC). Many studies that examined the behavioral effects of CBD concluded that it lacks the psychotomimetic ...
Douglas L. deAlmeida, Lakshmi A. Devi
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Plant Hormone Binding Sites [PDF]
Annals of Botany, 2004 Receptors for plant hormones are becoming identified with increasing rapidity, although a frustrating number remain unknown. There have also been many more hormone-binding proteins described than receptors. This Botanical Briefing summarizes what has been discovered about hormone binding sites, their discovery and descriptions, and will not dwell on ...
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A novel prediction method for protein DNA-binding residues based on neighboring residue correlations
Biotechnology & Biotechnological Equipment, 2022 Accurately identifying the protein DNA-binding residues is important for understanding the protein–DNA recognition mechanism and protein function annotation.
Jiazhi Song, Guixia Liu, Jingqing Jiang
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Amyloid and Tau Positron Emission Tomography Imaging in Alzheimer’s Disease and Other Tauopathies
Frontiers in Aging Neuroscience, 2022 The detection and staging of Alzheimer’s disease (AD) using non-invasive imaging biomarkers is of substantial clinical importance. Positron emission tomography (PET) provides readouts to uncover molecular alterations in the brains of AD patients with ...
Cinzia Maschio, Ruiqing Ni, Ruiqing Ni
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Frontiers in Endocrinology, 2017 Familial dysalbuminemic hyperthyroxinemia (FDH-T4) and hypertriiodothyroninemia (FDH-T3) are dominantly inherited syndromes characterized by a high concentration of thyroid hormone in the blood stream.
Ulrich Kragh-Hansen +2 more
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Antibodies, 2020 Plague is a zoonotic disease that is caused by Yersinia pestis. Monoclonal antibodies (mAbs) that bind to the V-antigen, a virulence factor that is produced by Y. pestis, can passively protect mice from plague. An analysis of protective mAbs that bind to
Kei Amemiya +11 more
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Open Medicine, 2021 Nuclear receptors (NRs) are ligand-activated transcription factors that regulate gene expression when bound to specific DNA sequences. Crosstalk between steroid NR systems has been studied for understanding the development of hormone-driven cancers but ...
Cruz Maria Araceli Diaz +5 more
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