Results 1 to 10 of about 172,469 (337)

Caveolin-Mediated Internalization of Fmoc-FF Nanogels in Breast Cancer Cell Lines

open access: yesPharmaceutics, 2023
Introduction: Hydrogel nanoparticles, also known as nanogels (NGs), have been recently proposed as alternative supramolecular vehicles for the delivery of biologically relevant molecules like anticancer drugs and contrast agents. The inner compartment of
Giovanni Smaldone   +6 more
doaj   +1 more source

Hairless canary seeds (Phalaris canariensis L.) as a potential source of antioxidant, antihypertensive, antidiabetic, and antiobesity biopeptides

open access: yesFood Production, Processing and Nutrition, 2021
Rising consumer concerns with synthetic drugs to treat non-communicable diseases (NCDs) have promoted a shift towards using natural biological active constituents that offer similar health benefits.
U. C. Urbizo-Reyes   +2 more
doaj   +1 more source

Vertebrate OTOP1 is also an alkali-activated channel

open access: yesNature Communications, 2023
pH sensation is critical for survival of vertebrates. Here, authors found six vertebrate OTOP1 channels that were highly conserved and directly activated by extracellular alkali.
Lifeng Tian   +7 more
doaj   +1 more source

Self-Supporting Hydrogels Based on Fmoc-Derivatized Cationic Hexapeptides for Potential Biomedical Applications

open access: yesBiomedicines, 2021
Peptide-based hydrogels (PHGs) are biocompatible materials suitable for biological, biomedical, and biotechnological applications, such as drug delivery and diagnostic tools for imaging.
Carlo Diaferia   +6 more
doaj   +1 more source

Fmoc-Diphenylalanine Hydrogels: Optimization of Preparation Methods and Structural Insights

open access: yesPharmaceuticals, 2022
Hydrogels (HGs) are tri-dimensional materials with a non-Newtonian flow behaviour formed by networks able to encapsulate high amounts of water or other biological fluids.
Carlo Diaferia   +3 more
doaj   +1 more source

Amyloid-Like Aggregation in Diseases and Biomaterials: Osmosis of Structural Information

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
The discovery that the polypeptide chain has a remarkable and intrinsic propensity to form amyloid-like aggregates endowed with an extraordinary stability is one of the most relevant breakthroughs of the last decades in both protein/peptide chemistry and
Nicole Balasco   +4 more
doaj   +1 more source

Blapstin, a Diapause-Specific Peptide-Like Peptide from the Chinese Medicinal Beetle Blaps rhynchopetera, Has Antifungal Function

open access: yesMicrobiology Spectrum, 2023
Drug resistance against bacteria and fungi has become common in recent years, and it is urgent to discover novel antimicrobial peptides to manage this problem.
La-Mei Zhang   +9 more
doaj   +1 more source

Probing protein sequences as sources for encrypted antimicrobial peptides [PDF]

open access: yes, 2012
Starting from the premise that a wealth of potentially biologically active peptides may lurk within proteins, we describe here a methodology to identify putative antimicrobial peptides encrypted in protein sequences.
Alan Cooper   +8 more
core   +10 more sources

Fabrication of fluorescent nanospheres by heating PEGylated tetratyrosine nanofibers

open access: yesScientific Reports, 2021
Aromatic polypeptides have recently drawn the interest of the research community for their capability to self-assemble into a variety of functional nanostructures.
Enrico Gallo   +8 more
doaj   +1 more source

Structure-Activity Relationship Investigations of Novel Constrained Chimeric Peptidomimetics of SOCS3 Protein Targeting JAK2

open access: yesPharmaceuticals, 2022
SOCS3 (suppressor of cytokine signaling 3) protein suppresses cytokine-induced inflammation and its deletion in neurons or immune cells increases the pathological growth of blood vessels. Recently, we designed several SOCS3 peptidomimetics by assuming as
Sara La Manna   +4 more
doaj   +1 more source

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