Self-assembly of Fmoc-tetrapeptides based on the RGDS cell adhesion motif [PDF]
, 2011 Self-assembly in aqueous solution has been investigated for two Fmoc [Fmoc ¼ N-(fluorenyl)-9-methoxycarbonyl] tetrapeptides comprising the RGDS cell adhesion motif from fibronectin or the scrambled sequence GRDS.
Alemán, Carlos +8 more
core +1 more source
DINeR: Database for Insect Neuropeptide Research [PDF]
, 2017 Neuropeptides are responsible for regulating a variety of functions, including development, metabolism, water and ion homeostasis, and as neuromodulators in circuits of the central nervous system.
Davies, Shireen-Anne +5 more
core +1 more source
Rigid Linkers for Bioactive Peptides [PDF]
Bioconjugate Chemistry, 2006 Rigid linkers of variable length were used to connect two high-affinity Nle4-D-Phe7-alpha-melanocyte stimulating hormone (NDP-alpha-MSH) or two low-affinity MSH(4) ligands. The linked peptides were synthesized by solid-phase methods. Control experiments indicate there is little or no effect of these linkers on NDP-alpha-MSH or MSH(4) binding to the ...
Josef, Vagner +7 more
openaire +2 more sources
Thermoregulatory role of ghrelin in the induction of torpor under a restricted feeding condition
Scientific Reports, 2021 Ghrelin, a circulating orexigenic hormone secreted from the stomach, stimulates appetite and food intake by activating the hypothalamic arcuate nucleus. Administration of exogenous ghrelin exerts anabolic effects, causing weight gain, increased adiposity,
Takahiro Sato +6 more
doaj +1 more source
Fibrin association at hybrid biointerfaces made of clot-binding peptides and polythiophene [PDF]
, 2016 The properties as biointerfaces of electroactive conducting polymer-peptide biocomposites formed by poly(3,4-ethylenedioxythiophene) (PEDOT) and CREKA or CR(NMe)EKA peptide sequences (where Glu has been replaced by N-methyl-Glu in the latter) have been ...
Agemy +50 more
core +4 more sources
Molecular basis for heat desensitization of TRPV1 ion channels
Nature Communications, 2019 The heat-sensitive ion channel TRPV1 is essential to temperature sensing in mammals and other animals. Here the authors find that the platypus form of TRPV1 does not desensitize, identify the mechanism underlying this property, and show that knock-in of ...
Lei Luo +8 more
doaj +1 more source
Design of decorated self-assembling peptide hydrogels as architecture for mesenchymal stem cells [PDF]
, 2016 Hydrogels from self-assembling ionic complementary peptides have been receiving a lot of interest from the scientific community as mimetic of the extracellular matrix that can offer three-dimensional supports for cell growth or can become vehicles for ...
Cavo, Marta +7 more
core +2 more sources
Targeted delivery of anti-inflammatory therapy to rheumatoid tissue by fusion proteins containing an IL-4-linked synovial targeting peptide [PDF]
, 2011 We provide first-time evidence that the synovial endothelium-targeting peptide (SyETP) CKSTHDRLC successfully delivers conjugated IL-4 to human rheumatoid synovium transplanted into SCID mice. SyETP, previously isolated by in vivo phage display and shown
Ahuva Nissim +10 more
core +1 more source
Hyaluronan and self-assembling peptides as building blocks to reconstruct the extracellular environment in skin tissue [PDF]
, 2013 Funding for this study was provided by the Portuguese Foundation for Science and Technology (FCT, grant PTDC/EBB-BIO/114523/2009). D. S.
Agren +50 more
core +1 more source
Halophiles and Their Biomolecules: Recent Advances and Future Applications in Biomedicine [PDF]
, 2020 The organisms thriving under extreme conditions better than any other organism living on Earth, fascinate by their hostile growing parameters, physiological features, and their production of valuable bioactive metabolites.
Amoozegar, Mohammad Ali +2 more
core +1 more source