Results 21 to 30 of about 174,581 (217)

Encapsulation of Trichoderma harzianum Preserves Enzymatic Activity and Enhances the Potential for Biological Control

Frontiers in Bioengineering and Biotechnology, 2020
Trichoderma harzianum is a biological control agent used against phytopathogens and biostimulation in agriculture. However, its efficacy can be affected by biotic and abiotic factors, and microencapsulation has been used to maximize the efficacy.
Cintia Rodrigues Maruyama, Cintia Rodrigues Maruyama, Natália Bilesky-José, Renata de Lima, Leonardo Fernandes Fraceto   +4 more
doaj   +1 more source

New Insights into the Metabolism of the Flavanones Eriocitrin and Hesperidin: A Comparative Human Pharmacokinetic Study

Antioxidants, 2021
The intake of hesperidin-rich sources, mostly found in orange juice, can decrease cardiometabolic risk, potentially linked to the gut microbial phase-II hesperetin derivatives.
María Ángeles Ávila-Gálvez, Juan Antonio Giménez-Bastida, Antonio González-Sarrías, Juan Carlos Espín   +3 more
doaj   +1 more source

Multitask Bioactivity Predictions Using Structural Chemical and Cell Morphology Information

, 2020
The understanding of the Mechanism-of-Action (MoA) of compounds and the prediction of potential drug targets has an important role in small-molecule drug discovery.
Lewis, Mervin, Noé, Sturm, Andreas, Bender, Ian, Barrett, Maria-Anna, Trapotsi, Avid M., Afzal, Ola, Engkvist   +6 more
core   +1 more source

Untargeted Metabolomics Reveals New Markers of Food Processing for Strawberry and Apple Purees

Molecules, 2022
In general, food processing and its conditions affect nutrients, bioactive compounds, and sensory characteristics of food products. This research aims to use a non-targeted metabolomics approach based on UPLC-ESI-QTOF-MS to determine how fruit processing
Gabriela Salazar-Orbea, Rocío García-Villalba, Luis M. Sánchez-Siles, Francisco A. Tomás-Barberán, Carlos J. García   +4 more
doaj   +1 more source

The Therapeutic Effect of Traditional Chinese Medicine on Inflammatory Diseases Caused by Virus, Especially on Those Caused by COVID-19

Frontiers in Pharmacology, 2021
Inflammasomes are large multimolecular complexes best recognized because of their ability to control activation of caspase-1, which in turn regulates the maturation of interleukin-18 (IL-18) and interleukin-1 β (IL-1β). IL-1β was originally identified as
Peng Li, Shuang Hu, Shuang Hu, Cheng Qian, Yan Yao, Yan Yao, Liang-yun Li, Liang-yun Li, Jun-fa Yang, Jun-fa Yang, Li Yang, Li Yang, Chen-chen Yang, Chen-chen Yang, Hong Zhou, Hong Zhou, Shu-xian Wang, Shu-xian Wang, Ying Hu, Ying Hu, Xing-yu Zhu, Jing Zhou, Jing Zhou, Lin-xin Pan, Chuan-pu Shen, Chuan-pu Shen, Huan Zhou   +26 more
doaj   +1 more source

There is No Distinctive Gut Microbiota Signature in the Metabolic Syndrome: Contribution of Cardiovascular Disease Risk Factors and Associated Medication

Microorganisms, 2020
The gut microbiota (GM) has attracted attention as a new target to combat several diseases, including metabolic syndrome (MetS), a pathological condition with many factors (diabetes, obesity, dyslipidemia, hypertension, etc.) that increase cardiovascular
Adrián Cortés-Martín, Carlos E. Iglesias-Aguirre, Amparo Meoro, María Victoria Selma, Juan Carlos Espín   +4 more
doaj   +1 more source

High–Pressure Processing vs. Thermal Treatment: Effect on the Stability of Polyphenols in Strawberry and Apple Products

Foods, 2021
Polyphenols are important bioactive compounds that are affected by processing. The consumer’s demand for minimally processed products contributes to the increase in non-thermal technologies such as high-pressure processing (HPP) in the food industry ...
Gabriela Lorena Salazar-Orbea, Rocío García-Villalba, Francisco A. Tomás-Barberán, Luis Manuel Sánchez-Siles   +3 more
doaj   +1 more source

Don’t overweight weights: Evaluation of weighting strategies for multi-task bioactivity classification models

, 2021
Machine learning models predicting the bioactivity of chemical compounds belong nowadays to the standard tools of cheminformaticians and computational medicinal chemists.
Simon, Harnqvist, Tobias, Morawietz, Bernd, Beck, Wouter, Heyndrickx, Adam, Zalewski, Lina, Humbeck, Noe, Sturm, Matthew, Holmes   +7 more
core   +1 more source

Anti-Hyperuricemic Effects of Extracts from Chaenomeles speciosa (Sweet) Nakai Fruits on Hyperuricemic Rats

Metabolites
Chaenomeles speciosa (Sweet) Nakai (C. speciosa) fruit has medicinal and food applications and exhibits beneficial pharmacological properties. This study aimed to explore the hypouricemic effect of C.
Ruoling Xu, Peng Deng, Yiren Ma, Kui Li, Fucai Ren, Ning Li   +5 more
doaj   +1 more source

Current Evidence on the Bioavailability of Food Bioactive Peptides

Molecules, 2020
Food protein-derived bioactive peptides are recognized as valuable ingredients of functional foods and/or nutraceuticals to promote health and reduce the risk of chronic diseases.
Lourdes Amigo, Blanca Hernández-Ledesma
doaj   +1 more source