Results 11 to 20 of about 10,988,700 (173)
iScience, 2023 Summary: The hippocampus plays a vital role in navigation, learning, and memory, and is affected in Alzheimer’s disease (AD). This study investigated the classification of AD-transgenic rats versus wild-type littermates using electrophysiological ...
Faraz Moradi +6 more
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iScience, 2021 Summary: In terms of genome and particle sizes, viruses exhibit great diversity. With the discovery of several nucleocytoplasmic large DNA viruses (NCLDVs) and jumbo phages, the relationship between particle and genome sizes has emerged as an important ...
Harshali V. Chaudhari +2 more
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The finite-volume method in computational rheology [PDF]
, 2012 The finite volume method (FVM) is widely used in traditional computational fluid dynamics (CFD), and many commercial CFD codes are based on this technique which is typically less demanding in computational resources than finite element methods (FEM ...
Pinho, F.T. +4 more
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2D effects enhance precision of gradient-based tissue patterning
iScience, 2023 Summary: Robust embryonic development requires pattern formation with high spatial accuracy. In epithelial tissues that are patterned by morphogen gradients, the emerging patterns achieve levels of precision that have recently been explained by a simple ...
Yuchong Long, Roman Vetter, Dagmar Iber
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The computational rules of cross-modality suppression in the visual posterior sylvian area
iScience, 2023 Summary: The macaque visual posterior sylvian area (VPS) is an area with neurons responding selectively to heading direction in both visual and vestibular modalities, but how VPS neurons combined these two sensory signals is still unknown. In contrast to
Bin Zhao +4 more
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Predicting Human Clinical Outcomes Using Mouse Multi-Organ Transcriptome
iScience, 2020 Summary: Approximately 90% of pre-clinically validated drugs fail in clinical trials owing to unanticipated clinical outcomes, costing over several hundred million US dollars per drug.
Satoshi Kozawa +5 more
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iScience, 2022 Summary: Single-cell transcriptomics enables the definition of diverse human immune cell types across multiple tissues and disease contexts. Further deeper biological understanding requires comprehensive integration of multiple single-cell omics ...
Congmin Xu +5 more
doaj +1 more source
Computational characterization of recombinase circuits for periodic behaviors
iScience, 2023 Summary: Recombinases are site-specific proteins found in nature that are capable of rearranging DNA. This function has made them promising gene editing tools in synthetic biology, as well as key elements in complex artificial gene circuits implementing ...
Judith Landau +3 more
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iScience, 2020 Summary: The mammalian circadian systems consist of indigenous, self-sustained 24-h rhythm generators. They comprise many genes, molecules, and regulators. To decode their systematic controls, a robust computational approach was employed.
Debajyoti Chowdhury +3 more
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iScience, 2021 Summary: The identification of proteins at the single-molecule level would open exciting new venues in biological research and disease diagnostics.
Carlos de Lannoy +3 more
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