Results 91 to 100 of about 431,520 (211)

Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis [PDF]

open access: yes, 2017
Macrophages specialize in removing lipids and debris present in the atherosclerotic plaque. However, plaque progression renders macrophages unable to degrade exogenous atherogenic material and endogenous cargo including dysfunctional proteins and ...
Ali, Sahl   +19 more
core   +2 more sources

Biogenesis, Composition and Potential Therapeutic Applications of Mesenchymal Stem Cells Derived Exosomes in Various Diseases

open access: yesInternational Journal of Nanomedicine, 2023
Yu-Guo Yuan,1,2 Jia-Lin Wang,1,2 Ya-Xin Zhang,1,2 Ling Li,1,2 Abu Musa Md Talimur Reza,3 Sangiliyandi Gurunathan4 1Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, People’s Republic of ...
Yuan YG   +5 more
doaj  

Biogenesis of cytochrome c in Neurospora crassa [PDF]

open access: yes, 1983
employed to study synthesis and intracellular transport of cytochrome c in Neurospora in vitro. 2. Apocytochrome c as well as holocytochrome c were found to be synthesized in a cell-free homogenate.
Hennig, Bernd, Neupert, Walter
core   +1 more source

Assessing mitochondria biogenesis [PDF]

open access: yesMethods, 2008
Mitochondria have their own DNA (mtDNA) and hence biogenesis of mitochondria requires a coordination of nuclear and mtDNA, both of which encode for mitochondria proteins. Our understanding of the molecular control of mitochondria biogenesis has increased in recent years, providing key signatures of the process.
openaire   +2 more sources

Normal Ribosomal Biogenesis but Shortened Protein Synthetic Response to Acute Eccentric Resistance Exercise in Old Skeletal Muscle. [PDF]

open access: yes, 2018
Anabolic resistance to feeding in aged muscle is well-characterized; however, whether old skeletal muscle is intrinsically resistant to acute mechanical loading is less clear.
Baar, Keith   +6 more
core  

A cell-based assay for CD63-containing extracellular vesicles [PDF]

open access: yes, 2019
Extracellular vesicles (EVs) are thought to be important in cell-cell communication and have elicited extraordinary interest as potential biomarkers of disease. However, quantitative methods to enable elucidation of mechanisms underlying release are few.
Cashikar, Anil G, Hanson, Phyllis I
core   +2 more sources

tRNA-derived small RNAs (tsRNAs) in cardiovascular diseases: biogenesis, functions, and therapeutic targets

open access: yesFrontiers in Cardiovascular Medicine
tRNA-derived small RNAs (tsRNAs) are a class of non-coding RNAs that are generated by cleavage of precursors or mature tRNAs under stress conditions such as hypoxia, oxidative stress and nutrient deficiency.
Chunfeng Xie   +6 more
doaj   +1 more source

The Yin and Yang of Microglia-Derived Extracellular Vesicles in CNS Injury and Diseases

open access: yesCells
Microglia, the resident immune cells of the central nervous system (CNS), play a crucial role in maintaining neural homeostasis but can also contribute to disease and injury when this state is disrupted or conversely play a pivotal role in neurorepair ...
Mousumi Ghosh, Damien D. Pearse
doaj   +1 more source

Extracellular vesicles in mycobacteria: new findings in biogenesis, host-pathogen interactions, and diagnostics

open access: yesmBio
Since the discovery of extracellular vesicles (EVs) in mycobacterial species 15 years back, we have learned that this phenomenon is conserved in the Mycobacterium genus and has critical roles in bacterial physiology and host-pathogen interactions ...
Vivian C. Salgueiro   +5 more
doaj   +1 more source

Lactic acid bacteria derived extracellular vesicles: emerging bioactive nanoparticles in modulating host health

open access: yesGut Microbes
Lactic acid bacteria derived extracellular vesicles (LAB-EVs) are nano-sized and carry a variety of biological cargoes. LAB-EVs have proven to be potential mediators of intercellular communication, serving not only the parental bacteria but also the host
Mohan Li   +6 more
doaj   +1 more source

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