Lysosomal Delivery of Bioactive Proteins to Living Human Cells via Engineered Exosomes [PDF]
Exosomes are naturally secreted nanovesicles derived from mammalian cells that are used for intercellular communication in vivo. As a result, they can potentially be used for intracellular delivery of therapeutics for disease treatment. We have developed
Levy, Daniel
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Misfolded proteins in the endoplasmic reticulum (ER) activate the unfolded protein response (U PR), which enhances protein folding to restore homeostasis.
Aviram +87 more
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Tenofovir disoproxil fumarate induces peripheral neuropathy and alters inflammation and mitochondrial biogenesis in the brains of mice. [PDF]
Mounting evidence suggests that antiretroviral therapy (ART) drugs may contribute to the prevalence of HIV-associated neurological dysfunction. The HIV envelope glycoprotein (gp120) is neurotoxic and has been linked to alterations in mitochondrial ...
Achim, Cristian L +11 more
core
Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission [PDF]
Agrawal +20 more
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Moxibustion delays ovarian aging by regulating mitochondrial biogenesis and improving oocyte quality. [PDF]
Yin Y +7 more
europepmc +1 more source
Regulation of chloroplast biogenesis and differentiation. [PDF]
Hernández-Verdeja T.
europepmc +1 more source
L-Leucine Upregulates Lysosomal Biogenesis and Autophagy to Lower Plaques in 5XFAD Mouse Model of Alzheimer's Disease. [PDF]
Paidi RK, Gorai S, Mondal S, Pahan K.
europepmc +1 more source
Ribosome Biogenesis and Translational Control in Skeletal Muscle Atrophy and Hypertrophy: Mechanisms and Therapeutic Perspectives. [PDF]
Xu M, Liu X.
europepmc +1 more source
Biogenesis and Regulation of Telomerase during Development and Cancer. [PDF]
Chen L, Batista LFZ.
europepmc +1 more source

