Arrdc4‐dependent extracellular vesicle biogenesis is required for sperm maturation
Extracellular vesicles (EVs) are important players in cell to cell communication in reproductive systems. Notably, EVs have been found and characterized in the male reproductive tract, however, direct functional evidence for their importance in mediating
Natalie J. Foot +10 more
doaj +1 more source
NCP activates chloroplast transcription by controlling phytochrome-dependent dual nuclear and plastidial switches. [PDF]
Phytochromes initiate chloroplast biogenesis by activating genes encoding the photosynthetic apparatus, including photosynthesis-associated plastid-encoded genes (PhAPGs).
Cao, Jun +10 more
core +2 more sources
Lipid droplet biogenesis [PDF]
Lipid droplets (LDs) are found in most cells, where they play central roles in energy and membrane lipid metabolism. The de novo biogenesis of LDs is a fascinating, yet poorly understood process involving the formation of a monolayer bound organelle from a bilayer membrane.
Florian, Wilfling +3 more
openaire +2 more sources
A comparative study of peroxisomal structures in Hansenula polymorpha pex mutants [PDF]
In a recent study, we performed a systematic genome analysis for the conservation of genes involved in peroxisome biogenesis (PEX genes) in various fungi.
Klei, Ida J. van der, +3 more
core +2 more sources
SND3 is the membrane insertase within a distinct SEC61 translocon complex
During the biogenesis of most eukaryotic integral membrane proteins (IMPs), transmembrane domains are inserted into the endoplasmic reticulum membrane by a dedicated insertase or the SEC61 translocon.
Tzu-Jing Yang +4 more
doaj +1 more source
There are no licensed vaccines against Shigella, a leading cause of children’s diarrhea and travelers’ diarrhea. To develop a cross-protective vaccine against heterogeneous Shigella species and serotypes, we attempted to apply an epitope- and structure ...
Aashwina Madhwal +3 more
doaj +1 more source
Circular RNAs—The Road Less Traveled
Circular RNAs are the most recent addition in the non-coding RNA family, which has started to gain recognition after a decade of obscurity. The first couple of reports that emerged at the beginning of this decade and the amount of evidence that has ...
Ashirbad Guria +3 more
doaj +1 more source
Mitochondrial Quality Control in Age-Related Pulmonary Fibrosis. [PDF]
Idiopathic pulmonary fibrosis (IPF) is age-related interstitial lung disease of unknown etiology. About 100,000 people in the U.S have IPF, with a 3-year median life expectancy post-diagnosis.
Cuevas-Mora, Karina +2 more
core +1 more source
Evolution of YidC/Oxa1/Alb3 insertases: three independent gene duplications followed by functional specialization in bacteria, mitochondria and chloroplasts [PDF]
Members of the YidC/Oxa1/Alb3 protein family facilitate the insertion, folding and assembly of proteins of the inner membranes of bacteria and mitochondria and the thylakoid membrane of plastids.
Funes, Soledad +4 more
core +1 more source
Regulatory roles of circular RNAs in poultry diseases: mechanisms and research advances
Research on circular RNA (circRNA) in poultry increasingly explores its role as a potential regulator in various diseases. It has also shown differential expression of circRNAs in infected tissues, signifying their participation in disease pathogenesis ...
Sumayya +9 more
doaj +1 more source

