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Algebraic Model Selection and Experimental Design in Biological Data Science [PDF]
Advances in Applied Mathematics, 133 (2022), 2021 Design of experiments and model selection, though essential steps in data science, are usually viewed as unrelated processes in the study and analysis of biological networks. Not accounting for their inter-relatedness has the potential to introduce bias and increase the risk of missing salient features in the modeling process.
arxiv +1 more source
Ciência & Educação (Bauru), 2021 Resumo: O artigo aborda o papel da formação científica inicial de professores por meio de atividades desenvolvidas no âmbito da disciplina Metodologia do Trabalho Científico em um curso de licenciatura em Ciências Biológicas. Apresenta e analisa reflexões em torno da construção dos fundamentos do trabalho científico, do reconhecimento das práticas que ...
openaire +5 more sources
Whole-brain optical access in a small adult vertebrate with two- and three-photon microscopy
iScience, 2022 Summary: Although optical microscopy has allowed scientists to study the entire brain in early developmental stages, access to the brains of live, adult vertebrates has been limited.
Najva Akbari +5 more
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iScience, 2022 Summary: Aortic endothelial cell dysfunction is an early trigger of atherosclerosis, the major cause of the cardiovascular disease (CVD). Nanomedicines targeting vascular endothelium and lesions hold great promise as therapeutic solutions to vascular ...
Yuxiang Zhou +9 more
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The RBPMSCreERT2-tdTomato mouse line for studying retinal and vascular relevant diseases
iScience, 2023 Summary: RNA-binding protein with multiple splicing (RBPMS) plays a crucial role in cardiac mesoderm specification and cardiovascular development, as well as being a typical marker for whole retinal ganglion cells (RGCs).
Guilan Li +6 more
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Circulating tumor cells: Towards mechanical phenotyping of metastasis
iScience, 2022 Summary: During cancer progression, metastatic dissemination accounts for ∼90% of death in patients. Metastasis occurs upon dissemination of circulating tumor cells (CTC) through body fluids, in particular the bloodstream, and several key steps remain ...
Marina Peralta +2 more
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iScience, 2022 Summary: We developed a workflow using multi-scale and multi-disciplinary experimental and computational approaches to analyze C-looping (the first phase of cardiac looping) of the chick across four developing hearts. We provide the first 3D datasets for
Nazanin Ebrahimi +5 more
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Imaging mass cytometry reveals the prominent role of myeloid cells at the maternal-fetal interface
iScience, 2022 Summary: Although the immunological complexity of the maternal-fetal interface is well appreciated, the actual interaction of maternal immune cells and fetal trophoblasts is insufficiently understood. To comprehend the composition and spatial orientation
Juliette Krop +18 more
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iScience, 2022 Summary: The United States Environmental Protection Agency (EPA) has been pursuing new high throughput in vitro assays to characterize endocrine disrupting chemicals (EDCs) that interact with estrogen receptor signaling.
Adam T. Szafran +3 more
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