Results 11 to 20 of about 60,317,274 (254)

Influence of data sampling methods on the representation of neural spiking activity in vivo

open access: yesiScience, 2022
Summary: In vivo single-unit recordings distinguish the basal spiking properties of neurons in different experimental settings and disease states. Here, we examined over 300 spike trains recorded from Purkinje cells and cerebellar nuclei neurons to test ...
Meike E. van der Heijden   +2 more
doaj   +1 more source

School of Biological Sciences News, 2023 [PDF]

open access: yes, 2023
Alumni newsletter of Illinois State University\u27s School of Biological Sciences.https://ir.library.illinoisstate.edu/anb/1007/thumbnail ...
School of Biological Sciences,
core   +2 more sources

The ex vivo pharmacology of HIV-1 antiretrovirals differs between macaques and humans

open access: yesiScience, 2022
Summary: Non-human primates (NHP) are widely used for the pre-clinical assessment of antiretrovirals (ARVs) for HIV treatment and prevention. However, the utility of these models is questionable given the differences in ARV pharmacology between humans ...
Carolina Herrera   +12 more
doaj   +1 more source

Integrative processing of untargeted metabolomic and lipidomic data using MultiABLER

open access: yesiScience, 2023
Summary: Mass spectrometry (MS)-based untargeted metabolomic and lipidomic approaches are being used increasingly in biomedical research. The adoption and integration of these data are critical to the overall multi-omic toolkit.
Ian C.H. Lee   +4 more
doaj   +1 more source

Mapping-friendly sequence reductions: Going beyond homopolymer compression

open access: yesiScience, 2022
Summary: Sequencing errors continue to pose algorithmic challenges to methods working with sequencing data. One of the simplest and most prevalent techniques for ameliorating the detrimental effects of homopolymer expansion/contraction errors present in ...
Luc Blassel, Paul Medvedev, Rayan Chikhi
doaj   +1 more source

Physical and chemical mechanisms of tissue optical clearing

open access: yesiScience, 2021
Summary: Advanced optical methods combined with various probes pave the way toward molecular imaging within living cells. However, major challenges are associated with the need to enhance the imaging resolution even further to the subcellular level for ...
Tingting Yu   +3 more
doaj   +1 more source

Acoustic camera system for measuring ultrasound communication in mice

open access: yesiScience, 2022
Summary: To investigate biological mechanisms underlying social behaviors and their deficits, social communication via ultrasonic vocalizations (USVs) in mice has received considerable attention as a powerful experimental model.
Jumpei Matsumoto   +7 more
doaj   +1 more source

School of Biological Sciences News, 2020-2021 [PDF]

open access: yes, 2020
Alumni newsletter of Illinois State University\u27s School of Biological Sciences.https://ir.library.illinoisstate.edu/anb/1006/thumbnail ...
School of Biological Sciences
core   +2 more sources

Rapid fluorescent vital imaging of olfactory epithelium

open access: yesiScience, 2022
Summary: Olfactory epithelium (OE) undergoes degeneration in disorders such as age-related and post-viral olfactory dysfunction. However, methods for real-time in vivo detection of OE and assessment of total extent within the nasal cavity are currently ...
Hironobu Nishijima   +6 more
doaj   +1 more source

School of Biological Sciences News, 2014 [PDF]

open access: yes, 2014
Alumni newsletter of Illinois State University\u27s School of Biological Sciences.https://ir.library.illinoisstate.edu/anb/1000/thumbnail ...
School of Biological Sciences
core   +2 more sources

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