Data integration in the era of omics: current and future challenges [PDF]
, 2018 To integrate heterogeneous and large omics data constitutes not only a conceptual challenge but a practical hurdle in the daily analysis of omics data.
Abugessaisa, Imad +9 more
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Rapid prototyping for biomedical engineering: current capabilities and Challenges [PDF]
, 2012 A new set of manufacturing technologies has emerged in the past decades to address market requirements in a customized way and to provide support for research tasks that require prototypes. These new techniques and technologies are usually referred to as
Andrés Díaz Lantada +21 more
core +2 more sources
iScience, 2023 Summary: Metastatic lesions produced through the process of systemic tumor cell dissemination and growth at distant sites are challenging to treat and the primary cause of patient mortality.
Sumreen Javed +4 more
doaj
Modelling Cell Cycle using Different Levels of Representation [PDF]
EPTCS 11, 2009, pp. 51-69, 2009 Understanding the behaviour of biological systems requires a complex setting of in vitro and in vivo experiments, which attracts high costs in terms of time and resources. The use of mathematical models allows researchers to perform computerised simulations of biological systems, which are called in silico experiments, to attain important insights and ...
arxiv +1 more source
Contributions of practices for biological research in initial teacher education [PDF]
, 2015 [Resumo] Neste artigo apresentamos reflexões sobre as disciplinas de Prática de Pesquisa Biológica I e II do curso de Licenciatura em Ciências Biológicas da Universidade Regional do Noroeste do Estado do Rio Grande do Sul - UNIJUI, Brasil.
Bianchi, Vidica +2 more
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Influence of data sampling methods on the representation of neural spiking activity in vivo
iScience, 2022 Summary: In vivo single-unit recordings distinguish the basal spiking properties of neurons in different experimental settings and disease states. Here, we examined over 300 spike trains recorded from Purkinje cells and cerebellar nuclei neurons to test ...
Meike E. van der Heijden +2 more
doaj
Control of Noise in Chemical and Biochemical Information Processing [PDF]
Israel J. Chem. 51, 118-131 (2011), 2010 We review models and approaches for error-control in order to prevent the buildup of noise when gates for digital chemical and biomolecular computing based on (bio)chemical reaction processes are utilized to realize stable, scalable networks for information processing.
arxiv +1 more source
The ex vivo pharmacology of HIV-1 antiretrovirals differs between macaques and humans
iScience, 2022 Summary: Non-human primates (NHP) are widely used for the pre-clinical assessment of antiretrovirals (ARVs) for HIV treatment and prevention. However, the utility of these models is questionable given the differences in ARV pharmacology between humans ...
Carolina Herrera +12 more
doaj
Mapping-friendly sequence reductions: Going beyond homopolymer compression
iScience, 2022 Summary: Sequencing errors continue to pose algorithmic challenges to methods working with sequencing data. One of the simplest and most prevalent techniques for ameliorating the detrimental effects of homopolymer expansion/contraction errors present in ...
Luc Blassel, Paul Medvedev, Rayan Chikhi
doaj
Practice-oriented controversies and borrowed epistemic credibility in current evolutionary biology: phylogeography as a case study [PDF]
, 2013 Although there is increasing recognition that theory and practice in science are intimately intertwined, philosophy of science perspectives on scientific controversies have been historically focused on theory rather than practice.
Arroyo-Santos, Alfonso +2 more
core +3 more sources