Results 21 to 30 of about 317,941 (266)
Acoustic camera system for measuring ultrasound communication in mice
iScience, 2022 Summary: To investigate biological mechanisms underlying social behaviors and their deficits, social communication via ultrasonic vocalizations (USVs) in mice has received considerable attention as a powerful experimental model.
Jumpei Matsumoto +7 more
doaj +1 more source
Rapid fluorescent vital imaging of olfactory epithelium
iScience, 2022 Summary: Olfactory epithelium (OE) undergoes degeneration in disorders such as age-related and post-viral olfactory dysfunction. However, methods for real-time in vivo detection of OE and assessment of total extent within the nasal cavity are currently ...
Hironobu Nishijima +6 more
doaj +1 more source
Biological nanopores for single-molecule sensing
iScience, 2022 Summary: Evolution has found countless ways to transport material across cells and cellular compartments separated by membranes. Protein assemblies are the cornerstone for the formation of channels and pores that enable this regulated passage of ...
Simon Finn Mayer +2 more
doaj +1 more source
The Rigor and Transparency Index Quality Metric for Assessing Biological and Medical Science Methods
iScience, 2020 Summary: The reproducibility crisis is a multifaceted problem involving ingrained practices within the scientific community. Fortunately, some causes are addressed by the author's adherence to rigor and reproducibility criteria, implemented via ...
Joe Menke +4 more
doaj +1 more source
BioMed Research International, 2023 The application of computational approaches in medical science for diagnosis is made possible by the development in technical advancements connected to computer and biological sciences.
Roshan Gangurde +6 more
semanticscholar +1 more source
iScience, 2023 Summary: Unpublished data and unused samples are common byproducts of research activity, but little is known about the scope and economic impact of their disuse.
Emma C. Bowers +3 more
doaj +1 more source
Precision vibratome for high-speed ultrathin biotissue cutting and organ-wide imaging
iScience, 2021 Summary: Cutting tissues into ultrathin slices is highly desired in sectioning-based organ-wide imaging. However, it is difficult to perform tissue cutting at a high speed with excellent quality.
Yafeng Li +8 more
doaj +1 more source
A light-switching pyrene probe to detect phase-separated biomolecules
iScience, 2021 Summary: Biomolecules may undergo liquid–liquid phase separation (LLPS) to spatiotemporally compartmentalize and regulate diverse biological processes. Because the number of tools to directly probe LLPS is limited (ie. FRAP, FRET, fluorescence microscopy,
Masaharu Hazawa +9 more
doaj +1 more source
Multiplexed protein profiling reveals spatial subcellular signaling networks
iScience, 2022 Summary: Protein-protein interaction networks are altered in multi-gene dysregulations in many disorders. Image-based protein multiplexing sheds light on signaling pathways to dissect cell-to-cell heterogeneity, previously masked by the bulk assays ...
Shuangyi Cai +7 more
doaj +1 more source
“Green Is the Color”: An Update on Ecofriendly Aspects of Organoselenium Chemistry
Molecules, 2022 Organoselenium compounds have been successfully applied in biological, medicinal and material sciences, as well as a powerful tool for modern organic synthesis, attracting the attention of the scientific community. This great success is mainly due to the
J. B. Azeredo +6 more
semanticscholar +1 more source