Results 11 to 20 of about 12,382 (217)
Beyond petrochemicals: challenges and opportunities in industrial-scale biomanufacturing [PDF]
Nature CommunicationsBiomanufacturing offers a sustainable alternative to petrochemical manufacturing by harnessing engineered microorganisms to convert renewable feedstocks into diverse value-added products. Systems metabolic engineering has driven its advancement, enabling
Ji Yeon Kim +3 more
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Harnessing the potential of machine learning for advancing “Quality by Design” in biomanufacturing
MAbs, 2022 Ensuring consistent high yields and product quality are key challenges in biomanufacturing. Even minor deviations in critical process parameters (CPPs) such as media and feed compositions can significantly affect product critical quality attributes (CQAs)
Say Kong Ng +2 more
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Rapid Fabrication of Cell-Laden Microfibers for Construction of Aligned Biomimetic Tissue
Frontiers in Bioengineering and Biotechnology, 2021 Bottom-up engineering of tissue constructs is being rapidly developed and broadly applied in biomanufacturing. As one type of building block, cell-laden microfibers are promising for reconstruction of oriented structures and functions of linear tissues ...
Bingchuan Lu +17 more
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Bioactive Materials, 2023 The bio-engineered ovary is an essential technology for treating female infertility. Especially the development of relevant in vitro models could be a critical step in a drug study.
Min Ye +11 more
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Developments and opportunities in continuous biopharmaceutical manufacturing
mAbs, 2021 Today’s biologics manufacturing practices incur high costs to the drug makers, which can contribute to high prices for patients. Timely investment in the development and implementation of continuous biomanufacturing can increase the production of ...
Ohnmar Khanal, Abraham M. Lenhoff
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Engineering, 2021 Inherent drawbacks associated with drug-eluting stents have prompted the development of bioresorbable cardiovascular stents. Additive manufacturing (3-dimentional (3D) printing) has been widely applied in medical devices.
Chengjin Wang +3 more
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Beyond omics: From descriptive profiling to causal and scalable design of fermentation microbiomes. [PDF]
ImetaFermentation microbiomes play essential roles in food production, feed preservation, waste valorization, and diverse sustainable industrial processes. Although multi‐omics and systems biology have substantially advanced our understanding of their assembly, interactions, and functional dynamics, industrial translation remains constrained by fragmented ...
Niu D +22 more
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Frontiers in Bioengineering and Biotechnology, 2023 Magnetosomes are biologically-derived magnetic nanoparticles (MNPs) naturally produced by magnetotactic bacteria (MTB). Due to their distinctive characteristics, such as narrow size distribution and high biocompatibility, magnetosomes represent an ...
Marta Masó-Martínez +8 more
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Microbial biomanufacturing for space-exploration—what to take and when to make
Nature Communications, 2023 As renewed interest in human space-exploration intensifies, a coherent and modernized strategy for mission design and planning has become increasingly crucial.
Nils J. H. Averesch +12 more
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Pharmaceutics, 2021 Outstanding progress has been achieved in developing therapeutic options for reasonably alleviating symptoms and prolonging the lifespan of patients suffering from myocardial infarction (MI).
Noelia Muñoz-Domínguez +3 more
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